Physiol. Res. 49: 659-664, 2000

Brain Activation during Volitional Control of Breathing


Institute of Pathophysiology, 1Institute of Functional Anatomy, Second Faculty of Medicine, Charles University and 2Institute of Clinical and Experimental Medicine, Prague, Czech Republic

Received November 18, 1999
Accepted March 21, 2000

Functional magnetic resonance imaging (fMRI) was used to demonstrate the brain activation during volitional control of breathing in nine healthy human subjects. This type of breathing was induced by acoustic stimuli dictating the respiratory frequency. During the period of dictated breathing not only the frontal and temporal lobes of the brain, but also the parietal lobes were bilaterally activated. The frontal lobe was activated bilaterally in all subjects, with frequent activation of Brodmann areas 4 and 6. In the parietal lobe, activation could mostly be demonstrated in gyrus postcentralis and the same was true for area 22 in the temporal lobe.

Key words
Respiratory control · Brain activation · Magnetic resonance · Hearing

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Doc. Dr. V. Šmejkal, CSc., Institute of Pathophysiology, Second Faculty of Medicine, Charles University, Plzeòská 221, 150 00 Prague 5, Czech Republic.

© 2000 by the Institute of Physiology, Czech Academy of Sciences