| The Effects of
Cardiopulmonary Bypass with Hollow Fiber Membrane
Oxygenator on Blood Clotting Measured by
Thromboelastography
M.
HORÁČEK, K. CVACHOVEC
Department of Anesthesiology and Critical Care
Medicine, Charles University, Second Faculty of
Medicine and Institute for Postgraduate Medical
Education, Prague, Czech Republic
Received February 8, 2001
Accepted August 3, 2001
Summary
In cardiac surgical patients we
investigated the effects of cardiopulmonary
bypass (CPB) with a hollow fiber membrane
oxygenator on blood clotting measured by
thromboelastography (TEG). We found only a
minimal change in the strength of blood clot
described either by the TEG parameter MA (maximum
amplitude) or by the shear modulus G calculated
from MA. After CPB there was also a significant
tendency towards hypercoagulation as defined by
shortened parameters R, K and increased ?-angle.
After comparison with published data obtained in
cardiac surgical patients using a bubble
oxygenator we conclude that currently used
extracorporeal technology exerts a less negative
influence on blood clotting than had been
conceived previously.
Key
words
Blood
clot · Thromboelastography · Cardiopulmonary
bypass · Bleeding · Oxygenator
Reprint
requests
Dr. M. Horáček, Department of Anesthesiology
and Critical Care Medicine, Motol University
Hospital, V Úvalu 84, 150 06 Prague 5, Czech
Republic.
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