Physiol. Res. 51: 541-556, 2002



Small Intestinal Manometry


Department of Surgical Gastroenterology D, Glostrup University Hospital of Copenhagen, Copenhagen, Denmark

Received December 1, 2001
Accepted March 20, 2002

Gastrointestinal motility is an integrated process including myoelectrical and contractile activity, tone, compliance and transit. The techniques for the assessment of gastrointestinal motility are multiple and all have their advantages and disadvantages. In the case of suspected abnormal upper gut transit, gastric and small bowel transit scintigraphy followed by small intestinal (antroduodenojejunalileal) manometry is recommended. Small bowel manometry can identify patterns suggestive of myopathy, neuropathy or obstruction. Information on procedures, indications, significance, pitfalls and guidelines for small bowel manometry is provided in this paper. In this context the potentials of small intestinal manometry for scientific experimental study of neurohumoral agents, such as serotonin receptor agonists and antagonists, on small intestinal motility is presented.

Key words
5-hydroxytryptamine · Enteric nervous system · Gastrointestinal · Hormones · Intestines · Manometry · Motility · Review · Serotonin · Small intestinal manometry

Reprint requests
Mark Berner Hansen, Chief Surgeon, DMSc., Department of Surgical Gastroenterology K, Bispebjerg University Hospital of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark. E-mail:

© 2002 by the Institute of Physiology, Czech Academy of Sciences

ISSN 0862 - 8408

Issue 6