Physiol. Res. 52: 137-140, 2003

SHORT COMMUNICATION


Heart Rate and Increased Intravascular Volume


M. SOUČEK, T. KÁRA, P. JURÁK1, J. HALÁMEK1, L. ŠPINAROVÁ, J. MELUZÍN, J. TOMAN, I. ŘIHÁČEK, J. ŠUMBERA, P. FRÁŇA

First Internal Cardio-Angiology Clinics, St. Anna Teaching Hospital, and 1Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, Brno, Czech Republic
 

Received December 10, 2001
Accepted May 22, 2002


Summary
The objective was to establish whether an intravascular volume increase leads to a heart rate (HR) increase without increased sympathetic tonus. HR changes at rest and at deep breathing (6/min – simulated increase of atrial filling pressure) were measured in patients after heart transplantation. Evaluation of dependency of HR changes on breathing depth was done through a new time series methodology. The data was evaluated through graphs displaying a significant increase in the graph area at deep breathing, when compared with breathing at rest (p < 0.01). We presume that an increase in HR corresponds to increased intravascular volume and malfunctioning kidneys.


Key words
Kidneys • Heart rate • Atrial mechanisms • Intravascular volume • Breathing


Reprint requests
Miroslav Souček, M.D., Ph.D. First Internal Cardio-Angiology Clinics, St. Anna Teaching Hospital, Pekařská 53, 656 91 Brno, Czech Republic. E-mail: miroslav.soucek@fnusa.cz


© 2003 by the Institute of Physiology, Czech Academy of Sciences