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“Genetic architecture of Prdm9-driven reproductive isolation between mouse subspecies” Hybrid incompatibility, the inviability or infertility of species hybrids, has played a central role in speciation research since Darwin's Origin of…
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ABC transporter blood-brain barrier function in neurodegenerative and neuroinflammatory diseases – from basic research to treatment Lecturer: Prof. Jens Pahnke, M.D., Ph.D., E.F.N./ University of Oslo, Faculty of Medicine / Oslo…
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Laboratory of Developmental Epileptology, IPHYS

“A chance for fertility despite bad DNA breaks (AKA The effect of crossing-over rate on fertility)” Programmed meiotic DNA breaks are essential for mammalian fertility but dangerous for genome integrity. DNA-binding…
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Dear Colleagues, We are pleased to announce the annual Mini-Symposium BIOCEV Regeneration III, which will be held on 23-24th November 2023 in BIOCEV, Vestec. Our symposium aims to exchange knowledge in regenerative…
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"Studying the eukaryotic cilium by a single organelle approach" Cilia are present on the surface of many eukaryotic cells and have critical motility, sensory, and signalling functions. Yet, many fundamental…
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Sensorineural hearing loss in mice lacking GABAB receptor-associated KCTD12 protein Lecturer: Mgr. Adolf Melichar / Department of Auditory Neuroscience Annotation: KCTD12 protein is the auxiliary subunit of the G-protein coupled receptor for γ-aminobutyric…
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“Canonical RNAi in vivo in mice” Canonical RNAi, i.e. long dsRNA-induced mRNA degradation, is essentially not operating in vivo in mammalian somatic cells. Low efficiency of dsRNA conversion into small…
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"The impact of FAM84B in retinal homeostasis" Fam84b is an incompletely characterised protein. Its aberrant expression has been associated with various human cancers, with a possible reported role in endosomal…
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Improvement of healing of bone defects by new approaches of regenerative medicine Lecturer: Mgr. Eva Šebová / Department of Tissue Engineering Annotation: The PLA and PCL block copolymer combined with hydroxyapatite nanoparticles is a…
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“The novel sphingolipid synthesis regulators in cell life” Sphingolipids are bioactive lipids and critical structural components of cell membranes. Regulation of their de novo synthesis is critical for normal mammalian…
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