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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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DTSTART:20230326T010000
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DTSTART:20231029T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20231213T150000
DTEND;TZID=Europe/Prague:20231213T160000
DTSTAMP:20260419T005911
CREATED:20231204T124646Z
LAST-MODIFIED:20231204T152228Z
UID:732-1702479600-1702483200@www.biomed.cas.cz
SUMMARY:Seminář - Valeria Buccheri\, M.Sc.
DESCRIPTION:“Canonical RNAi in vivo in mice” \nCanonical RNAi\, i.e. long dsRNA-induced mRNA degradation\, is essentially not operating in vivo in mammalian somatic cells. Low efficiency of dsRNA conversion into small interfering RNA by Dicer was identified as key limiting factor for canonical RNAi in mammals. We have genetically engineered mice to express a more active Dicer variant and investigated how this impacts mouse development and RNAi activity in vivo.
URL:https://www.biomed.cas.cz/event/seminar-valeria-buccheri-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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