BEGIN:VCALENDAR
VERSION:2.0
PRODID:-// - ECPv6.6.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240214T150000
DTEND;TZID=Europe/Prague:20240214T160000
DTSTAMP:20260417T180654
CREATED:20240130T112256Z
LAST-MODIFIED:20240130T112256Z
UID:778-1707922800-1707926400@www.biomed.cas.cz
SUMMARY:Seminář Miroslav Stoyanov\, M.Sc.
DESCRIPTION:“PPM1D activity promotes genome instability and cellular transformation” \nProtein phosphatase magnesium dependent 1 (PPM1D) is a negative regulator of the tumour suppressor p53 and is implicated in termination of DNA damage response. Increased PPM1D activity allows proliferation in the presence of DNA breaks caused by ionizing radiation or replication stress induced by expression of active RAS oncogene. Active PPM1D promotes cell growth in the soft agar and formation of tumours in nude mice confirming the oncogenic potential of PPM1D.
URL:https://www.biomed.cas.cz/event/seminar-miroslav-stoyanov-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
END:VCALENDAR