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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20240331T010000
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DTSTART:20241027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20240522
DTEND;VALUE=DATE:20240525
DTSTAMP:20260418T065355
CREATED:20240409T092424Z
LAST-MODIFIED:20240409T092424Z
UID:871-1716336000-1716595199@www.biomed.cas.cz
SUMMARY:IEM CAS Entry Level Super-Resolution Microscopy
DESCRIPTION:Basic Information\nThe course covers theoretical and practical aspects of an “entry-level” super-resolution imaging methods based on the principle of Optical-Photon-Reassignment available in our facility at confocal microscopes Zeiss LSM880\nwith AiryScan and Olympus SpinSR10 with OSR. \nWhat is meant by “Entry-Level Super-Resolution Microscopy”? It is a group of methods that improve resolution by a factor of ~2 over diffraction-limited imaging and are very easy to use. While these methods cannot offer the resolution improvement of factor 5x-10x like STED or STROM/PALM\, they are fast\, easy to operate and require no special sample preparation or extra skills. They are also very suitable for live cell imaging. \n\nDuration: 3 days\nLanguage: English\nLocation: IEM library\, microscope rooms\n\nRegistration form and more information can be found on our website.
URL:https://www.biomed.cas.cz/event/iem-cas-entry-level-super-resolution-microscopy/
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DTSTART;TZID=Europe/Prague:20240522T150000
DTEND;TZID=Europe/Prague:20240522T160000
DTSTAMP:20260418T065355
CREATED:20240513T113032Z
LAST-MODIFIED:20240513T113032Z
UID:909-1716390000-1716393600@www.biomed.cas.cz
SUMMARY:Seminář Vadym Sulimenko\, Ph.D.
DESCRIPTION:“Differential roles of GIT1 and GIT2 adaptor proteins in regulating microtubule nucleation in glioblastoma cells” \nMicrotubules play a critical role in cell division and migration\, impacting the viability and invasiveness of malignant tumors. Although the reorganization of highly dynamic microtubules is central to these processes\, the precise mechanism underlying microtubule involvement in glioblastoma cell motility remains poorly understood. G protein-coupled receptor kinase-interacting proteins (GITs) are GTPase-activating proteins (GAPs) for ADP-ribosylation factor (Arf) small GTPases. GITs are structurally conserved multidomain scaffold/adaptor proteins that link Arf GTPases to other intracellular signaling events. Here we show that the signalling proteins GIT1 and GIT2 form complexes with γ-Tubulin ring complexes (γTuRCs)\, associate with centrosomes and differentially regulate microtubule nucleation and cell migration in glioblastoma cells.
URL:https://www.biomed.cas.cz/event/seminar-vadym-sulimenko-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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