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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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DTSTART:20240331T010000
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DTSTART;TZID=Europe/Prague:20241009T150000
DTEND;TZID=Europe/Prague:20241009T160000
DTSTAMP:20260418T065404
CREATED:20241001T064659Z
LAST-MODIFIED:20241001T064659Z
UID:2166-1728486000-1728489600@www.biomed.cas.cz
SUMMARY:Seminář Kristína Jamrichová\, M.Sc.
DESCRIPTION:“Investigating the Impact of Cullin-Dependent Degradation on Protein Homeostasis” \nCullin-dependent ligases (CRLs) regulate cellular homeostasis by targeting proteins for degradation. Mutations and alterations in the CRL substrate receptor FBXO38 have been linked to distal muscular atrophy\, chronic obstructive pulmonary disease\, and gender dysphoria. In our previous research\, we demonstrated that FBXO38 controls centromeric chromatin density during spermatogenesis. We will present our progress in deciphering FBXO38 function\, particularly in the context of protein homeostasis and ribosomal activity. \n 
URL:https://www.biomed.cas.cz/event/seminar-kristina-jamrichova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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