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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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TZOFFSETFROM:+0100
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DTSTART:20240331T010000
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DTSTART:20241027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20241104
DTEND;VALUE=DATE:20241108
DTSTAMP:20260418T053731
CREATED:20241018T065127Z
LAST-MODIFIED:20241101T113003Z
UID:2201-1730678400-1731023999@www.biomed.cas.cz
SUMMARY:3-day course on Single cell analysis - from qPCR to sequencing
DESCRIPTION:This course will provide valuable insights and practical skills in the rapidly evolving field of single cell analyses and spatial transcriptomics. With a maximum of 10 participants\, you’ll receive personalized attention and the opportunity to engage deeply with the subject. \nIf you’re interested in joining us\, please respond via email to sindelka@ibt.cas.cz as soon as possible\, as space is limited. \nWe look forward to an enriching experience together!
URL:https://www.biomed.cas.cz/event/3-day-course-on-single-cell-analysis-from-qpcr-to-sequencing/
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20241107
DTEND;VALUE=DATE:20241108
DTSTAMP:20260418T053731
CREATED:20241021T122515Z
LAST-MODIFIED:20241021T122515Z
UID:2209-1730937600-1731023999@www.biomed.cas.cz
SUMMARY:Den otevřených dveří - FGÚ
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri-fgu-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241107T140000
DTEND;TZID=Europe/Prague:20241107T150000
DTSTAMP:20260418T053731
CREATED:20241014T093123Z
LAST-MODIFIED:20241101T163717Z
UID:2177-1730988000-1730991600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 11/2024
DESCRIPTION:Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation\nLecturer: Satyendra Mondal\, MSc. / Department of Functional Organisation of Biomembranes \nAnnotation: The regulation of eukaryotic gene expression via mRNA degradation is an evolutionarily conserved process\, with the 5′-3′ exoribonuclease 1 (Xrn1) playing a pivotal role. In yeast\, following the depletion of fermentable carbon source\, Xrn1 is sequestered at the plasma membrane-associated protein complex\, the eisosome\, where it becomes inactive. In this study\, we show that the plasma membrane localisation of Xrn1 requires the core eisosome components and identify a putative eisosome-binding domain of Xrn1. Our findings demonstrate that the eisosome binding of Xrn1 is subject to the halting of ongoing glycolytic flux rather than the availability of fermentable carbon sources. Furthermore\, we show that the localisation of the human orthologue of Xrn1 resembles that of its yeast counterpart when expressed in yeast. Our results advance our understanding of the plasma membrane-associated regulation of Xrn1 and indicate that the regulation principle may be evolutionarily conserved from yeast to humans. \nThe seminar will take place on 7. 11. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-11-2024/
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