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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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DTSTART:20250330T010000
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DTSTART:20251026T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250319T150000
DTEND;TZID=Europe/Prague:20250319T160000
DTSTAMP:20260419T162903
CREATED:20250310T081141Z
LAST-MODIFIED:20250310T081141Z
UID:2326-1742396400-1742400000@www.biomed.cas.cz
SUMMARY:Seminář Jakub Sumbal
DESCRIPTION:“Probing the functional heterogeneity and hierarchy in mammary gland fibroblasts” \nIn this talk\, I will focus on the heterogeneity and hierarchy of mouse mammary fibroblasts – the predominant cell type of mammary stroma. By single cell RNA sequencing\, genetic lineage tracing and microscopy we show that fibroblast transcriptomic clusters represent spatially differentiated populations with specific functions. Moreover\, we used the lineage tracing to show differentiation traits within fibroblast populations and other stromal cell types. Finally\, I will discuss how the regulation of fibroblast differentiation may be important for proper organ morphogenesis and cancer progression.
URL:https://www.biomed.cas.cz/event/seminar-jakub-sumbal/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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