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TZID:Europe/Prague
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DTSTART:20250330T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251210T150000
DTEND;TZID=Europe/Prague:20251210T160000
DTSTAMP:20260419T065050
CREATED:20251202T071927Z
LAST-MODIFIED:20251202T071927Z
UID:2465-1765378800-1765382400@www.biomed.cas.cz
SUMMARY:Seminář Jakub Rídl
DESCRIPTION:“Enigmatic germline-restricted chromosome of songbirds has different centromere compared to regular chromosomes” \nCentromeres are an important part of chromosomes which direct chromosome segregation during cell division. Their modifications can therefore explain the unusual mitotic and meiotic behaviour of certain chromosomes\, such as the germline-restricted chromosome (GRC) of songbirds. This chromosome is eliminated from somatic cells during early embryogenesis and later also from male germ cells during spermatogenesis. We used a combination of cytogenetic and genomic approaches to identify the centromeric sequences of two closely related songbird species\, the common nightingale (Luscinia megarhynchos) and the thrush nightingale (L. luscinia). We found a 436-bp satellite repeat present in the centromeric regions of all regular chromosomes (i.e.\, autosomes and sex chromosomes). Interestingly\, hybridization of the probe to this repeat on meiotic spreads suggested that this repeat is missing on the GRC. Our results indicate that the change of the centromeric sequence may underlie the unusual inheritance and programmed DNA elimination of the GRC in songbirds.
URL:https://www.biomed.cas.cz/event/seminar-jakub-ridl/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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