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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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DTSTART:20260329T010000
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DTSTART:20261025T010000
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DTSTART;VALUE=DATE:20261012
DTEND;VALUE=DATE:20261017
DTSTAMP:20261014T072700
CREATED:20260616T064901Z
LAST-MODIFIED:20260616T064901Z
UID:2554-1791763200-1792195199@www.biomed.cas.cz
SUMMARY:Course “Microscopy Methods in Biomedicine”
DESCRIPTION:Dear Colleagues\, \n  \nThe Institute of Molecular Genetics CAS together with the research infrastructure Czech-BioImaging would like to invite you to attend the course “Microscopy methods in biomedicine”\, which will be held on 12. – 16. 10. 2026 in Prague. \nThe five-day theoretical course with practical demonstrations and exercises\, is devoted to modern methodologies of light and electron microscopy. The program of the course is updated every year to reflect new trends in microscopy. The course covers general methods and fundamental approaches in microscopy\, as well as cutting edge techniques like super-resolution light microscopy\, fast confocal spinning disc acquisition or light sheet microscopy and imaging of whole living organisms. \n  \nThe course is intended for PhD students and young researchers in the biomedical fields. \n  \nThe course is taught in English. \n  \nThe registration deadline is 25 September 2026 \n  \nFor more information and registration please visit the course’s webpage https://course.img.cas.cz/mmib/ \n  \nWe look forward to seeing you in Prague! \nBest regards\, \nOrganizers
URL:https://www.biomed.cas.cz/event/course-microscopy-methods-in-biomedicine/
LOCATION:IMG
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DTSTART;TZID=Europe/Prague:20261014T150000
DTEND;TZID=Europe/Prague:20261014T160000
DTSTAMP:20261014T072700
CREATED:20261008T083900Z
LAST-MODIFIED:20261008T083900Z
UID:2578-1791990000-1791993600@www.biomed.cas.cz
SUMMARY:Seminar Hynek Wichterle
DESCRIPTION:“Turning back the clock on neurodegeneration: transcriptional rejuvenation of motor neurons” \nTo paraphrase Dobzhansky’s famous aphorism: nothing in neuroscience makes sense except in the light of motor behavior. Our work focuses on spinal motor neurons – the final common path in motor control and the primary target of degeneration in amyotrophic lateral sclerosis (ALS). Leveraging developmental insights from human and mouse stem-cell models\, we aim to divert motor neurons from vulnerable\, disease-sensitive states into resilient phenotypes while preserving their physiological function. To achieve this\, we pursue a dual strategy:\n1) Targeted Pharmacology: We developed novel kinase inhibitors that counteract motor neuron vulnerability to endoplasmic reticulum (ER) and proteostatic stress; shared pathogenic drivers across ALS\, Parkinson’s\, Huntington’s\, and Alzheimer’s diseases.\n2) Transcriptional Reprogramming: We established approaches to rejuvenate motor neurons\, bolstering their capacity to clear misfolded proteins\, and methods to reprogram them toward subtype identities naturally resistant to ALS pathology. By dissecting the genetic programs governing neuronal specification and maturation\, we seek to establish conceptually novel therapeutic paradigms to halt neurodegeneration.
URL:https://www.biomed.cas.cz/event/seminar-hynek-wichterle/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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