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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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BEGIN:VTIMEZONE
TZID:Europe/Prague
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20240331T010000
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DTSTART:20241027T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240603T150000
DTEND;TZID=Europe/Prague:20240603T160000
DTSTAMP:20260414T191738
CREATED:20240509T101513Z
LAST-MODIFIED:20240509T101513Z
UID:905-1717426800-1717430400@www.biomed.cas.cz
SUMMARY:Lecture "How are the epilepsy molecular clocks ticking?"
DESCRIPTION:Cristina Reschke\, RCSI University of Medicine and Health Sciences\, School of Pharmacy and Biomolecular Sciences\, Dublin\, Ireland
URL:https://www.biomed.cas.cz/event/lecture-how-are-the-epilepsy-molecular-clocks-ticking-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240605T150000
DTEND;TZID=Europe/Prague:20240605T160000
DTSTAMP:20260414T191738
CREATED:20240528T080600Z
LAST-MODIFIED:20240528T080600Z
UID:922-1717599600-1717603200@www.biomed.cas.cz
SUMMARY:Seminář Subhadip Chakraborty\, M.Sc.
DESCRIPTION:“Understanding the mechanochemical transitions that underlie early embryo development” \nDuring embryogenesis a single fertilized oocyte develops into an adult organism via tightly controlled patterns of cell division\, cell polarization and cell movements. These mechanical processes depend on the actomyosin cortex\, a thin 2D layer that resides underneath the plasma membrane. Importantly\, for normal development the actomyosin cortex in rapidly dividing embryonic cells needs to transition between contractile and non-contractile phases. Surprisingly little is known about how these mechanical transitions are regulated in a developing embryo. To understand mechanical transitions during embryogenesis\, I use C. elegans early embryos as a model\, and perform quantitative live imaging of the actomyosin cortex as it transitions between contractile and non-contractile phases. In the IMG seminar I will present my recent results in which we demonstrate how two major signaling cascades\, Cdc42 and RhoA\, affect distinct mechanical phases and the transitions between them.
URL:https://www.biomed.cas.cz/event/seminar-subhadip-chakraborty-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240606T140000
DTEND;TZID=Europe/Prague:20240606T150000
DTSTAMP:20260414T191738
CREATED:20240523T221435Z
LAST-MODIFIED:20240523T223848Z
UID:917-1717682400-1717686000@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 06/2024
DESCRIPTION:Open Access Publishing & Green Open Access\nLecturer: Arzuv Caryjeva\, Ph.D. / Data Manager / Director’s Secretariat \nAnnotation: The Open Science requirements of project funders and available options and tools to satisfy these requirements will be introduced. Mainly\, Open access publishing and the green route to ensure open access to Scientific articles will be discussed. Moreover\, there will be an introduction to the Institutional data repository and how researchers can use it. This seminar is particularly important for lab leaders and grant holders. \nThe seminar will take place on 6. 6. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-06-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240612
DTEND;VALUE=DATE:20240615
DTSTAMP:20260414T191738
CREATED:20240507T075917Z
LAST-MODIFIED:20240507T075917Z
UID:893-1718150400-1718409599@www.biomed.cas.cz
SUMMARY:Practical course SUPER-RESOLUTION IN LIGHT MICROSCOPY
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/practical-course-super-resolution-in-light-microscopy/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T130000
DTEND;TZID=Europe/Prague:20240612T140000
DTSTAMP:20260414T191738
CREATED:20240523T224952Z
LAST-MODIFIED:20240917T083407Z
UID:919-1718197200-1718200800@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures Seminar Series: Digital Image Basics
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThe seminar aims to provide participants with the basic knowledge and skills to work with graphics and digital images. The participants will be introduced to key concepts and techniques. For example\, they will learn how information is stored in a digital image or what bit depth is. Understanding these principles is essential for the proper processing of microscopic data. \nThe seminar will take place on 12.6.2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come. \nLecturer\nJan Setnička
URL:https://www.biomed.cas.cz/event/919/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T150000
DTEND;TZID=Europe/Prague:20240612T160000
DTSTAMP:20260414T191738
CREATED:20240603T095411Z
LAST-MODIFIED:20240603T095411Z
UID:924-1718204400-1718208000@www.biomed.cas.cz
SUMMARY:Seminář Jiří Březina\, M.Sc.
DESCRIPTION:“How antigens get distributed in the thymus” \nThe presentation of self-antigens in the thymus by medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) is crucial for the establishment of central tolerance. While mTECs produce and present self-antigens in an autonomous manner\, DCs acquire them from mTECs by cooperative antigen transfer (CAT). Although CAT represents a key process of central tolerance\, molecular determinants which define CAT’s effectivity as well as the the capacity of DCs to subsequently present highjacked antigens are largely unknown. To reveal the nature of these determinants\, we compared the transcriptomes of CAT-experienced and inexperienced DCs via scRNAseq. In this seminar\, we will focus on one such a determinant of CAT\, gene product encoding the tight junction protein\, CLAUDIN 1. A series of experiments demonstrated  that CLAUDIN 1 is a regulatory molecule which coordinates CAT and T cell selection processes. The comprehension of these processes will aid in the resolution of the current controversy concerning the role of DCs in central tolerance.
URL:https://www.biomed.cas.cz/event/seminar-jiri-brezina-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240617T163000
DTEND;TZID=Europe/Prague:20240617T173000
DTSTAMP:20260414T191738
CREATED:20240509T101609Z
LAST-MODIFIED:20240509T101609Z
UID:907-1718641800-1718645400@www.biomed.cas.cz
SUMMARY:Lecture "Obesity cannot be cured\, but increasingly better treated"
DESCRIPTION:Prof. Matthias Blüher\, Director of the Helmholtz Institute for Metabolism\, Obesity and Vasculature research at the Helmholtz Center Munich and the University of Leipzig\, Germany
URL:https://www.biomed.cas.cz/event/lecture-obesity-cannot-be-cured-but-increasingly-better-treated/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240619T150000
DTEND;TZID=Europe/Prague:20240619T160000
DTSTAMP:20260414T191738
CREATED:20240611T060610Z
LAST-MODIFIED:20240611T060610Z
UID:930-1718809200-1718812800@www.biomed.cas.cz
SUMMARY:Seminář Josef Novák\, Ph.D.
DESCRIPTION:“Switch of ADP/ATP translocase isoforms in cellular senescence and malignancy” \nFour isoforms of human ATD/ADP translocators (ANTs) have poorly understood functional differences. Due to their high sequence similarity\, antibody-based detection of these proteins is challenging. We\, therefore\, developed a sensitive proteomic method for detecting ATD/ADP translocator isoforms and their relative ratio. Using this technique\, we observed a switch of ANT isoforms during senescence establishment associated with changes in cellular energy metabolism. The switch of ANT protein isoforms was not correlated with the change of ANT transcripts. Similarly\, we found a non-correlation of ANT transcripts with corresponding proteins in patients‘ glioblastoma and lung cancer samples. We concluded that protein levels of ANT isoforms are regulated on multiple levels and are tightly linked to mitochondria biogenesis.
URL:https://www.biomed.cas.cz/event/seminar-josef-novak-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240620T100000
DTEND;TZID=Europe/Prague:20240620T113000
DTSTAMP:20260414T191738
CREATED:20240605T102859Z
LAST-MODIFIED:20240605T102859Z
UID:927-1718877600-1718883000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR pro funkční období 2025–2029 - Ing. Jiří Plešek\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR\nprof. RNDr. Evě Zažímalové\, CSc. Volba kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024. \n\n\n\nJedním z kandidátů na předsedu AV ČR je Ing. Jiří Plešek\, CSc.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-pro-funkcni-obdobi-2025-2029-ing-jiri-plesek-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240625T130000
DTEND;TZID=Europe/Prague:20240625T140000
DTSTAMP:20260414T191738
CREATED:20240917T083708Z
LAST-MODIFIED:20240917T083708Z
UID:2140-1719320400-1719324000@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures: Checklists for Publishing Images and Introduction to Image Archives
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers‘ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers‘ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThanks to speedy technological developments\, microscopy images document a significant part of scientific discoveries in this data-intensive era. It is becoming increasingly important to ensure that images are presented in a transparent and reproducible manner. However\, there are only a few guidelines available for publishing terabytes to petabytes of image data\, while research funding agencies require data to be published in open repositories. The objective of this seminar is to provide an overview of the key aspects of data publication\, with a particular focus on image data. In addition\, the seminar will offer a brief introduction to repositories and other relevant resources. \nThe seminar will take place on 25. 6. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come.
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclectures-checklists-for-publishing-images-and-introduction-to-image-archives/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240626T160000
DTEND;TZID=Europe/Prague:20240626T170000
DTSTAMP:20260414T191738
CREATED:20240612T073038Z
LAST-MODIFIED:20240612T081932Z
UID:932-1719417600-1719421200@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dirk Schübeler
DESCRIPTION:“Finding your place: Transcription factors as sensors and modifiers of chromatin” \nTranscription factors only bind a minority of their motifs in large mammalian genomes. One likely explanation is that many motifs are not accessible for binding due to the action of chromatin and DNA methylation. We are using mammalian stem cell models and their differentiation combined with genomics to understand this important interplay between gene regulation\, chromatin structure and DNA methylation. We study the dynamics of the epigenome and test regulatory models in cellular models by genetic perturbation and genome editing approaches. \nI will discuss our recent efforts in understanding how the sensitivity to DNA methylation and nucleosomes can limit transcription factor binding in the context of the cell and how TFs rely on specific chromatin remodelers for access to their binding sites.
URL:https://www.biomed.cas.cz/event/seminar-prof-dirk-schubeler/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
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