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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
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BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20241104
DTEND;VALUE=DATE:20241108
DTSTAMP:20260418T080854
CREATED:20241018T065127Z
LAST-MODIFIED:20241101T113003Z
UID:2201-1730678400-1731023999@www.biomed.cas.cz
SUMMARY:3-day course on Single cell analysis - from qPCR to sequencing
DESCRIPTION:This course will provide valuable insights and practical skills in the rapidly evolving field of single cell analyses and spatial transcriptomics. With a maximum of 10 participants\, you’ll receive personalized attention and the opportunity to engage deeply with the subject. \nIf you’re interested in joining us\, please respond via email to sindelka@ibt.cas.cz as soon as possible\, as space is limited. \nWe look forward to an enriching experience together!
URL:https://www.biomed.cas.cz/event/3-day-course-on-single-cell-analysis-from-qpcr-to-sequencing/
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241107
DTEND;VALUE=DATE:20241108
DTSTAMP:20260418T080854
CREATED:20241021T122515Z
LAST-MODIFIED:20241021T122515Z
UID:2209-1730937600-1731023999@www.biomed.cas.cz
SUMMARY:Den otevřených dveří - FGÚ
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri-fgu-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241107T140000
DTEND;TZID=Europe/Prague:20241107T150000
DTSTAMP:20260418T080854
CREATED:20241014T093123Z
LAST-MODIFIED:20241101T163717Z
UID:2177-1730988000-1730991600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 11/2024
DESCRIPTION:Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation\nLecturer: Satyendra Mondal\, MSc. / Department of Functional Organisation of Biomembranes \nAnnotation: The regulation of eukaryotic gene expression via mRNA degradation is an evolutionarily conserved process\, with the 5′-3′ exoribonuclease 1 (Xrn1) playing a pivotal role. In yeast\, following the depletion of fermentable carbon source\, Xrn1 is sequestered at the plasma membrane-associated protein complex\, the eisosome\, where it becomes inactive. In this study\, we show that the plasma membrane localisation of Xrn1 requires the core eisosome components and identify a putative eisosome-binding domain of Xrn1. Our findings demonstrate that the eisosome binding of Xrn1 is subject to the halting of ongoing glycolytic flux rather than the availability of fermentable carbon sources. Furthermore\, we show that the localisation of the human orthologue of Xrn1 resembles that of its yeast counterpart when expressed in yeast. Our results advance our understanding of the plasma membrane-associated regulation of Xrn1 and indicate that the regulation principle may be evolutionarily conserved from yeast to humans. \nThe seminar will take place on 7. 11. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-11-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241111T150000
DTEND;TZID=Europe/Prague:20241111T160000
DTSTAMP:20260418T080854
CREATED:20241021T122639Z
LAST-MODIFIED:20241021T122639Z
UID:2211-1731337200-1731340800@www.biomed.cas.cz
SUMMARY:Lecture „Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-tissue-specific-sex-dependent-difference-in-the-metabolism-of-fatty-acid-esters-of-hydroxy-fatty-acids/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241113T150000
DTEND;TZID=Europe/Prague:20241113T160000
DTSTAMP:20260418T080854
CREATED:20241104T072334Z
LAST-MODIFIED:20241104T072334Z
UID:2247-1731510000-1731513600@www.biomed.cas.cz
SUMMARY:Seminář Aleš Neuwirth\, Ph.D.
DESCRIPTION:“Unravelling autoimmunity in Addison’s disease using a new mouse model” \nAutoimmune Addison’s disease is a disorder targeting steroid-producing cells in the adrenal glands. Due to the lack of suitable animal models\, the immune mechanisms underlying adrenal destruction remain largely unknown. To address this\, we developed the first defined mouse model of experimental autoimmune adrenalitis by immunizing C57BL/6 mice with immunogenic peptides derived from CYP11A1\, a rate-limiting enzyme in steroidogenesis. This model allows us to study the pathogenesis of Addison’s disease and provides a unique opportunity to investigate the fate decisions of self-reactive CD4+ T cells and their clonal lineages in a well-defined autoimmune setting.
URL:https://www.biomed.cas.cz/event/seminar-ales-neuwirth-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241118T160000
DTEND;TZID=Europe/Prague:20241118T170000
DTSTAMP:20260418T080854
CREATED:20241021T122808Z
LAST-MODIFIED:20241021T122808Z
UID:2213-1731945600-1731949200@www.biomed.cas.cz
SUMMARY:Lecture „The role of cornichons in the biogenesis and functioning of monovalent-cation transport systems“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-the-role-of-cornichons-in-the-biogenesis-and-functioning-of-monovalent-cation-transport-systems/
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241119T090000
DTEND;TZID=Europe/Prague:20241119T140000
DTSTAMP:20260418T080854
CREATED:20241101T113131Z
LAST-MODIFIED:20241101T113131Z
UID:2245-1732006800-1732024800@www.biomed.cas.cz
SUMMARY:Den otevřených dveří
DESCRIPTION:Prohlídka laboratoří\, ukázky experimentů v oblasti molekulární genetiky\, imunologie\, buněčné biologie\, virologie\, prohlídka posterů a diskuse k vybraným tématům.
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241120T150000
DTEND;TZID=Europe/Prague:20241120T160000
DTSTAMP:20260418T080854
CREATED:20241104T072502Z
LAST-MODIFIED:20241120T070615Z
UID:2249-1732114800-1732118400@www.biomed.cas.cz
SUMMARY:Seminář doc. Mgr. Lumír Krejčí\, Ph.D. - ZRUŠENO
DESCRIPTION:“Homologous Recombination – From Repair of DSBs to Processing Stalled Replication Forks and Human Diseases” \nOur lab focuses on the mechanisms ensuring accurate DNA replication and the role of homologous recombination (HR) in preventing genome instability. We investigate how endogenous hard-to-replicate regions\, G-quadruplexes (G4) and R-loops\, impact replication and contribute to disease development. A key aspect involves studying the formation and regulation of RAD51 filaments during HR. We explore how positive regulators like BRCA2 and RAD51 paralogs promote filament assembly and its stability\, while negative regulators like RECQ5 and RECQ4 helicase help balance replication stress and genome stability.
URL:https://www.biomed.cas.cz/event/seminar-doc-mgr-lumir-krejci-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241121T110000
DTEND;TZID=Europe/Prague:20241121T120000
DTSTAMP:20260418T080854
CREATED:20241111T071221Z
LAST-MODIFIED:20241111T071221Z
UID:2253-1732186800-1732190400@www.biomed.cas.cz
SUMMARY:Seminář Matthias G. Fischer
DESCRIPTION:Max Planck Institute for Medical Research\, Heidelberg \n“Viruses of unicellular eukaryotes: A tale of giants and hyperparasites” \nViruses of protists play important roles in ecology and evolution by influencing microbial population dynamics and shaping eukaryotic genomes by endogenization. Of particular interest are complex DNA viruses whose particle and genome sizes overlap with those of bacteria. In this talk\, I will highlight some remarkable properties of these giant viruses and explore their relationship with smaller DNA viruses\, called virophages\, which can parasitize giant viruses and thus act as an antiviral defense system in certain protist species.
URL:https://www.biomed.cas.cz/event/seminar-matthias-g-fischer/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241125T150000
DTEND;TZID=Europe/Prague:20241125T160000
DTSTAMP:20260418T080854
CREATED:20241021T122910Z
LAST-MODIFIED:20241021T122910Z
UID:2215-1732546800-1732550400@www.biomed.cas.cz
SUMMARY:18th BioCEV-Krč Methodological Seminar
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/18th-biocev-krc-methodological-seminar/
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241126T100000
DTEND;TZID=Europe/Prague:20241126T173000
DTSTAMP:20260418T080854
CREATED:20241115T065915Z
LAST-MODIFIED:20241115T070057Z
UID:2256-1732615200-1732642200@www.biomed.cas.cz
SUMMARY:IEM CAS - BIOCEV Regeneration IV
DESCRIPTION:We are pleased to announce the annual mini-symposium BIOCEV Regeneration IV\, which will be held on November 26th\, 2024\, in BIOCEV Centre\, Vestec. \nBIOCEV Regeneration is an annual open one-day mini-symposium that brings together researchers from different fields of biomedicine\, from regenerative medicine and tissue engineering to cancer research\, drug discovery\, and cryobiology. \nThis year\, the BIOCEV Regeneration IV will focus on the exciting field of cryobiology and cryobanking and highlight its important role in state-of-the-art biomedical research. The mini-symposium is endorsed by the international Society for Low Temperature Biology (SLTB) and will bring together keynote speakers and young researchers from different biomedical disciplines\, employing low temperatures in their research and development. This year we will focus on two major directions of cryobiology: cryotechnologies in clinically-oriented research (ATMP production\, cell and tissue banking for therapy and diagnostics) and biodiversity preservation and regeneration. \nThe mini-symposium will be held in the main conference hall and surrounding spaces of the BIOCEV and broadcast online. \nAlong with several lectures given by our invited speakers\, we encourage early career researchers to contribute to our symposium and share achievements in stem cell research\, tissue engineering\, 3D culture\, cancer research or cryobiology during the poster session. \nThe event is free of charge. More information can be found in the official invitation. \nWe look forward to seeing you. \n  \nRegistration
URL:https://www.biomed.cas.cz/event/iem-cas-biocev-regeneration-iv/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241127T080000
DTEND;TZID=Europe/Prague:20241129T170000
DTSTAMP:20260418T080854
CREATED:20240917T090109Z
LAST-MODIFIED:20241014T102557Z
UID:2148-1732694400-1732899600@www.biomed.cas.cz
SUMMARY:IEM CAS Introduction to Programming for Image Processing 2024
DESCRIPTION:Due to reaching capacity for in-person participation\, registration is now only available for online attendance. Thank you for your understanding.  \nBasic information\nThe course is tailored to users already familiar with the basics of image processing. It will be focused on automatization\, high throughput and basic scripting. Course participants will learn how to create and edit macros in ImageJ and how to write more sophisticated scripts for batch processing. Furthermore\, they will learn the basics of image processing in Matlab and Cellpose. \nDuration: 3 days \nLanguage: English \nProgramme\nLocation: Turquoise Auditorium \nSpeakers: Barbora Hyklová\, Štěpán Kortus\, Iva Švecová\, Jakub Zahumenský \nDay 1 / Wednesday / 27. 11. 2024\n\nIntroduction\, macro recording and editing in ImageJ\nWriting a complex macro for batch processing – automatic data import\, cell segmentation\, measurements\, export in organized format\n\nDay 2 / Thursday / 28. 11. 2024\n\nScript automation\, ImageJ customization\nCell segmentation using Cellpose and integration of Cellpose into the workflow\nDemonstration of a complex ImageJ/Cellpose workflow\n\nDay 3 / Friday / 29.11. 2024\n\nOptional: Discussion of individual projects and data analysis questions. \n\nRequirements\nPrior Experience with ImageJ: Participants should have a basic familiarity with ImageJ and its fundamental features. They should be comfortable with tasks like image import\, basic processing (e.g.\, brightness/contrast adjustments)\, and measurements.  \nOwn laptop: Participants are required to bring their own laptop for hands-on exercises. If you do not have access to a laptop\, please inform us in advance\, and we will provide you with one. Prior to the event\, you will receive a list of required software programs to install for the course. \n\n\n\n\n\n\n\n\n\n\nRegistration\nRegistration here: free of charge \n  \n\n\n 
URL:https://www.biomed.cas.cz/event/introduction-to-programming-for-image-processing-2024-preliminary-date/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241127T150000
DTEND;TZID=Europe/Prague:20241127T160000
DTSTAMP:20260418T080854
CREATED:20241118T123730Z
LAST-MODIFIED:20241118T123730Z
UID:2260-1732719600-1732723200@www.biomed.cas.cz
SUMMARY:Seminář Michaela Procházková\, M.Sc.
DESCRIPTION:“CRL4COP1 ubiquitination complex as a balancer of early odontogenesis” \nCullin-RING ubiquitin ligase (CRL) complexes have been heavily studied in connection to cancer progression but there is limited evidence about their physiological roles. One of the exceptions is disruption of limb development by thalidomide induced by inhibition of CRL4 complex via regulation of Fgf8 (Ito et al.\, 2010). Notably\, Fgf8 expressing population is essential also for development of tooth primordia and we found CRL4 genes to be specifically expressed within odontognic epithelium. We further identified COP1 as a substrate binding protein which can bind ETS transcription factors\, downstream targets of Fgf pathway\, and unveiled that conditional deletion of CRL4 genes severly affects size and morphology of molar primordia and future teeth.
URL:https://www.biomed.cas.cz/event/seminar-michaela-prochazkova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
END:VCALENDAR