BEGIN:VCALENDAR
VERSION:2.0
PRODID:-// - ECPv6.6.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250602T150000
DTEND;TZID=Europe/Prague:20250602T160000
DTSTAMP:20260420T065632
CREATED:20250305T115745Z
LAST-MODIFIED:20250305T115745Z
UID:2319-1748876400-1748880000@www.biomed.cas.cz
SUMMARY:Přednáška pro nevědce a nevědkyně - V. Varga
DESCRIPTION:„Cesta do nitra buňky“ \nBěhem přednášky podnikneme cestu do nitra živé buňky. Ukážeme si\, jaké nástroje vědci používají\, aby odhalili její mikroskopické struktury\, a jak lze tyto detaily převést do podoby\, kterou můžeme spatřit\npouhým okem. Zároveň zjistíme něco překvapivého – naše buňky mají víc společného\, než byste čekali\, s buňkami nebezpečných parazitů\, například s původcem spavé nemoci. Jak moc jsme si podobní a co to pro nás znamená? To vše odhalíme v průběhu přednášky.
URL:https://www.biomed.cas.cz/event/prednaska-pro-nevedce-a-nevedkyne-v-varga/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250604T150000
DTEND;TZID=Europe/Prague:20250604T160000
DTSTAMP:20260420T065633
CREATED:20250423T100816Z
LAST-MODIFIED:20250423T100816Z
UID:2368-1749049200-1749052800@www.biomed.cas.cz
SUMMARY:Seminář Piergiorgio Percipalle
DESCRIPTION:“Chromatin Architecture and Gene Regulation by Actin and Myosin in Health and Disease” \nChromosomes are arranged in distinct chromosome territories\, within which chromatin is further organized into chromatin compartments and topologically associating domains (TADs). By orchestrating DNA loops and promoter-enhancer interactions\, this spatial organization of the genome plays a crucial role in gene expression and ultimately has a critical impact on cell identity. Disruptions in these hierarchical layers of genome organization can lead to aberrant expression of entire gene programs\, contributing to various diseases\, including metabolic and genetic disorders. Understanding these spatial features provides critical insights into genome function and potential therapeutic strategies. Architectural proteins such as CTCF and cohesin have been shown to play key roles in genome organization. In this talk\, I will primarily focus on the critical role of nuclear actin and myosin in regulating 3D genome organization at the chromatin level and how these mechanisms\, once impaired\, affect metabolic reprogramming in the context of tumorigenesis and differentiation\, including adipogenesis.
URL:https://www.biomed.cas.cz/event/seminar-piergiorgio-percipalle/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250615
DTEND;VALUE=DATE:20250623
DTSTAMP:20260420T065633
CREATED:20250321T112735Z
LAST-MODIFIED:20250321T112735Z
UID:2344-1749945600-1750636799@www.biomed.cas.cz
SUMMARY:EMBO Practical Course "Super-resolution in Light Microscopy"
DESCRIPTION:Dear Colleagues\, \n  \nWe are pleased to announce the upcoming EMBO Practical Course „Super-resolution in Light Microscopy\,“ \ntaking place from June 15–22\, 2025\, Institute of Molecular Genetics of the Czech Academy of Sciences (IMG) in Prague. \n  \nThis 8-day course combines theoretical talks\, lectures from leading experts in the field\, and practical demonstrations with hands-on sessions using advanced microscopy systems. \n  \nFollowing the introductory day\, the course is structured into three thematic 2-day blocks: \n\nConfocal-based super-resolution (optical/mathematical reassignment\, adaptive deconvolution\, and radial fluctuations)\nStructured Illumination Microscopy (SIM)\nNanoscopy techniques (Single-Molecule Localization Microscopy – SMLM\, and Stimulated Emission Depletion microscopy – STED)\n\nThe last day is focused on deconvolution of SR images and QC approaches. \n  \nFor the course\, we have gathered an outstanding group of international experts who will deliver lectures and keynotes and participate actively in practical demonstrations. Leading microscopy companies will provide their latest super-resolution systems\, with application specialists guiding dedicated hands-on sessions. \n  \nThe course is ideally suited for biologists\, microscopy facility staff\, and imaging specialists who wish to enhance their practical expertise and remain at the forefront of microscopy innovations. \n  \nThe registration deadline is April 14\, 2025. \nThe course is offered in a hybrid format: 20 in-person seats and 25 virtual participant slots are available.  \n  \nCourse in numbers: \n16 expert lectures and keynotes by global leaders in microscopy. \n38 intensive practical hours to master super-resolution techniques. \n12 advanced microscopy systems from industry-leading producers. \n4 interactive discussions exploring specialized microscopy topics. \n3 amazing social events for networking with experts \n  \nDetailed course information and registration are available at: \nhttps://meetings.embo.org/event/25-superres-light-microscopy \n  \nProgramme overview: \nhttps://meetings.embo.org/files/2025-03/embo-practical-course-srlm-2025-overview.pdf \n  \nYou can follow us on: \nInstagram: https://www.instagram.com/embo_pc_srlm/  \nFacebook: https://www.facebook.com/embopcsrlm/  \n  \nWe encourage you to apply soon and look forward to welcoming you to Prague! \n  \nBest regards\, \n  \nEMBO Organizing Team
URL:https://www.biomed.cas.cz/event/embo-practical-course-super-resolution-in-light-microscopy/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250623T150000
DTEND;TZID=Europe/Prague:20250623T160000
DTSTAMP:20260420T065633
CREATED:20250319T134811Z
LAST-MODIFIED:20250319T135059Z
UID:2334-1750690800-1750694400@www.biomed.cas.cz
SUMMARY:Prof. Bradley Launikonis\, The University of Queensland\, Brisbane\, Australia
DESCRIPTION:Lecture „The role of ryanodine receptors in muscle function“ \nRyanodine receptors (RyR) are the Ca2+ release channel of skeletal muscle\, which are responsible for rapidly releasing a large amount of Ca2+ upon electrical stimulation to evoke contraction. In the resting muscle\, RyR leak Ca2+ and require the expenditure of energy to maintain steady state Ca2+ content of the intracellular Ca2+ store. It is this function that regulates multiple processes in the muscle\, including the regulation of Ca2+ permeability of the plasma membrane and distribution of Ca2+ across the intracellular compartments\, non-shivering thermogenesis and adaptation to changes in muscle activity. In this talk I will describe how RyR basal function controls the movements of Ca2+ between cellular compartments following changes in the RyR due to mutations\, intense exercise and changes in activity. To do this I will present novel techniques for measuring Ca2+ movements and heat generation within the fibre that we have used in conjunction with muscle from transgenic mice and fibres isolated from biopsies of human muscle.
URL:https://www.biomed.cas.cz/event/lecture-the-role-of-ryanodine-receptors-in-muscle-function/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250623T150000
DTEND;TZID=Europe/Prague:20250623T160000
DTSTAMP:20260420T065633
CREATED:20250423T073953Z
LAST-MODIFIED:20250423T073953Z
UID:2366-1750690800-1750694400@www.biomed.cas.cz
SUMMARY:Lecture „The role of ryanodine receptors in muscle function“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-the-role-of-ryanodine-receptors-in-muscle-function-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20250625T150000
DTEND;TZID=Europe/Prague:20250625T160000
DTSTAMP:20260420T065633
CREATED:20250617T070133Z
LAST-MODIFIED:20250617T070133Z
UID:2386-1750863600-1750867200@www.biomed.cas.cz
SUMMARY:Seminář Rositsa Maystorova\, M.Sc.
DESCRIPTION:“Ontogeny of zebrafish erythropoietic waves” \nHematopoiesis is the process of blood formation\, which occurs in multiple waves during vertebrate development. In zebrafish\, the first wave initiates before 24 hours post-fertilization with the generation of primitive myeloid cells from cephalic mesoderm and primitive erythrocytes in the intermediate cell mass. The first definitive wave is transient\, and it produces erythro-myeloid progenitors in the posterior blood island at 26-30hpf. The next definitive wave forms hematopoietic stem cells from the aortic endothelium\, which migrate to the caudal hematopoietic tissue\, and later colonize the kidneys and thymus. Despite the importance of zebrafish as a model organism\, it has been challenging to study the erythroid waves in fish in detail\, and our knowledge about these processes is limited and predominantly focused on their emergence. Through our work\, we are providing more information on the dynamics of the erythroid waves\, as well as globin gene expression patterns in the primitive and definitive populations. Additionally\, we have managed to identify novel factors playing a role in the globin switch from larval to adult globins.
URL:https://www.biomed.cas.cz/event/seminar-rositsa-maystorova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
END:VCALENDAR