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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
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TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251001T150000
DTEND;TZID=Europe/Prague:20251001T160000
DTSTAMP:20260420T152300
CREATED:20250922T140000Z
LAST-MODIFIED:20250922T140000Z
UID:2408-1759330800-1759334400@www.biomed.cas.cz
SUMMARY:Seminář Vadym Sulimenko
DESCRIPTION:“Regulation of microtubule organization in glioblastoma cells by GIT2 phosphorylation” \nGlioblastoma\, the most aggressive common type of brain cancer in humans\, carries a very poor prognosis for patient survival. Microtubules are critical for cell division and mesenchymal migration\, processes that strongly influence tumor viability and invasiveness. While the reorganization of highly dynamic microtubules is central to these events\, the mechanisms by which microtubules contribute to glioblastoma cell motility remain poorly understood. We previously demonstrated that ARF GTPase-activating proteins (GITs) associate with γ-tubulin ring complex (γTuRC) proteins. Here\, we show that GIT2 localizes to centrosomes\, regulates microtubule organization and cell motility. Our findings indicate that the ArfGAP domain of GIT2 and protein kinase C (PKC) are essential for controlling microtubule nucleation. Furthermore\, we demonstrate that glioblastoma cells can be effectively treated with newly developed functionalized upconverting nanoparticles (UCNPs)\, which represent a promising new approach for photodynamic therapy of glioblastoma.
URL:https://www.biomed.cas.cz/event/seminar-vadym-sulimenko/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251008T150000
DTEND;TZID=Europe/Prague:20251008T160000
DTSTAMP:20260420T152300
CREATED:20250924T150118Z
LAST-MODIFIED:20250924T150118Z
UID:2414-1759935600-1759939200@www.biomed.cas.cz
SUMMARY:Seminář Katarína Ondrušková
DESCRIPTION:“How Cells Keep DNA Replication in Check” \nAccurate DNA replication is the foundation of genome stability and cell survival. Our study uncovers a key “gatekeeper” complex that ensures the molecular machinery starting DNA replication is properly assembled and regulated. When this control breaks down\, replication becomes uncoordinated\, leading to stress\, genetic instability\, and changes often seen in cancer cells. By revealing this hidden layer of replication control\, our work opens new opportunities to understand how cells protect their genomes and how these mechanisms could be exploited in cancer therapy. \n 
URL:https://www.biomed.cas.cz/event/seminar-katarina-ondruskova/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251015T150000
DTEND;TZID=Europe/Prague:20251015T160000
DTSTAMP:20260420T152300
CREATED:20251008T123139Z
LAST-MODIFIED:20251008T123139Z
UID:2418-1760540400-1760544000@www.biomed.cas.cz
SUMMARY:Seminář Kihyuck Kwak
DESCRIPTION:Department of Microbiology\, College of Medicine\, Yonsei University\, Seoul\, South Korea \n“Intrinsic mechanisms governing B cell discrimination between self and non-self antigens”
URL:https://www.biomed.cas.cz/event/seminar-kihyuck-kwak/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251023T130000
DTEND;TZID=Europe/Prague:20251023T160000
DTSTAMP:20260420T152300
CREATED:20251013T071221Z
LAST-MODIFIED:20251013T071221Z
UID:2423-1761224400-1761235200@www.biomed.cas.cz
SUMMARY:100th anniversary of the birth of Prof. Milan Hašek
DESCRIPTION:Dear colleagues and friends\, \nThis year marks the 100th anniversary of the birth of Prof. Milan Hašek (October 4\, 1925)\,\na giant of Czech immunology. He was not only an outstanding scientist\, immunologist\,\nbiologist\, and physician\, but also an inspiring mentor to an entire generation of researchers\,\nmany of whom emigrated after 1968 and became respected ambassadors of Czech immunology\nabroad. His insatiable curiosity\, innovative spirit\, and experimental precision\, often bordering\non genius\, earned him worldwide recognition as a co-discoverer of immune tolerance.\nWhen this year’s Nobel laureate in Physiology or Medicine\, Prof. Shimon Sakaguchi\, was\ninvited to Prague\, his response was clear: “I would be delighted to visit the country that gave\nthe world Milan Hašek.” \nWe are pleased to invite you to a mini-conference dedicated to the centennial of Prof. Milan\nHašek’s birth.\n📅 October 23\, 2025\n📍 Hašek Lecture Hall\, Institute of Molecular Genetics\, Czech Academy of Sciences\n🕐 1:00–4:00 PM (followed by refreshments) \nInvited speakers include:\n• Prof. MUDr. Juraj Ivanyi\, Emeritus Professor of Immunology of Infectious Diseases\,\nKing’s College London\, long-term collaborator and close friend of Prof. Hašek\n• Prof. RNDr. Vladimír Holáň\, DrSc.\, leading Czech immunologist specializing in\ntransplant immunology and immunoregulation\, former researcher at the Institute of\nExperimental Medicine of the CAS and Prof. Hašek’s last PhD student\n• RNDr. Jiří Hejnar\, CSc.\, Head of the Laboratory of Viral and Cellular Genetics\, IMG\nCAS\, expert in endogenous retroviruses\, viral receptors\, and gene editing in poultry\n• Mgr. Ondřej Štěpánek\, Ph.D.\, Head of the Laboratory of Adaptive Immunity\, holder\nof the EMBO Installation and ERC Starting Grants\, and Horizon Europe Grant\, focused\non fundamental aspects of T-cell biology in infection\, cancer\, and autoimmunity\n• Mgr. Jan Dobeš\, Ph.D.\, Head of the Laboratory of Microbial Immunity\, Department\nof Cell Biology\, Faculty of Science\, Charles University; recipient of the Česká hlava\n“Invence” Award (2023)\, “ACTERIA Early Career Research Prize”\, and grants Junior\nStar\, Primus\, and ERC.CZ\, focused on peripheral tolerance and gut immunity\n• Mgr. Matouš Vobořil\, Ph.D.\, Head of the newly established Laboratory of Viral\nImmunology\, Department of Cell Biology\, Faculty of Science\, Charles University;\nlaureate of the Česká hlava “Doctorandus” Award (2020) and holder of Junior Star and\nPrimus grants\, focused on immune tolerance and antiviral immunity\n• Mgr. Jiří Březina\, Ph.D.\, Postdoctoral researcher at VIB Ghent\, Belgium – studying\nnovel mechanisms underlying the establishment of central tolerance \nWe warmly look forward to seeing you and celebrating the scientific legacy of Prof. Milan\nHašek together. \nRNDr. Petr Dráber\, DrSc.\, MUDr. Luca Vannucci\, PhD.\, RNDr. Dominik Filipp\, CSc. \n  \n 
URL:https://www.biomed.cas.cz/event/100th-anniversary-of-the-birth-of-prof-milan-hasek/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20251029T150000
DTEND;TZID=Europe/Prague:20251029T160000
DTSTAMP:20260420T152300
CREATED:20251013T073543Z
LAST-MODIFIED:20251013T073543Z
UID:2426-1761750000-1761753600@www.biomed.cas.cz
SUMMARY:Seminář Rositsa Maystorova
DESCRIPTION:“Ontogeny of zebrafish erythropoietic waves” \nHematopoiesis is the process of blood formation\, which occurs in multiple waves during vertebrate development. In zebrafish\, the first wave initiates before 24 hours post-fertilization with the generation of primitive myeloid cells from cephalic mesoderm and primitive erythrocytes in the intermediate cell mass. The first definitive wave is transient\, and it produces erythro-myeloid progenitors in the posterior blood island at 26-30hpf. The next definitive wave forms hematopoietic stem cells from the aortic endothelium\, which migrate to the caudal hematopoietic tissue\, and later colonize the kidneys and thymus. Despite the importance of zebrafish as a model organism\, it has been challenging to study the erythroid waves in fish in detail\, and our knowledge about these processes is limited and predominantly focused on their emergence. Through our work\, we are providing more information on the dynamics of the erythroid waves\, as well as globin gene expression patterns in the primitive and definitive populations. Additionally\, we have managed to identify novel factors playing a role in the globin switch from larval to adult globins.
URL:https://www.biomed.cas.cz/event/seminar-rositsa-maystorova/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251031
DTEND;VALUE=DATE:20251101
DTSTAMP:20260420T152300
CREATED:20250306T130439Z
LAST-MODIFIED:20250306T130439Z
UID:2322-1761868800-1761955199@www.biomed.cas.cz
SUMMARY:RNA Club
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/rna-club/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
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