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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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TZID:Europe/Prague
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TZOFFSETFROM:+0100
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DTSTART:20260329T010000
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DTSTART:20261025T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260421
DTEND;VALUE=DATE:20260424
DTSTAMP:20260429T082302
CREATED:20260223T091341Z
LAST-MODIFIED:20260223T091341Z
UID:2489-1776729600-1776988799@www.biomed.cas.cz
SUMMARY:Innovation Days in Bioscience Imaging – Vision for Life
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/innovation-days-in-bioscience-imaging-vision-for-life/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20260422T150000
DTEND;TZID=Europe/Prague:20260422T160000
DTSTAMP:20260429T082302
CREATED:20260414T123612Z
LAST-MODIFIED:20260422T074024Z
UID:2522-1776870000-1776873600@www.biomed.cas.cz
SUMMARY:Seminář Karolina Kowalska
DESCRIPTION:“Mechanisms of MICAL regulation in actin filament disassembly” \nActin oxidation at specific methionine residues is a distinctive mechanism that drives actin filament disassembly. This process is mediated by the cytoskeletal effector MICAL\, which selectively associates with and oxidizes actin filaments\, thereby promoting their disassembly. MICAL-dependent actin oxidation is essential for axon guidance and also contributes to other biological processes\, including angiogenesis\, vesicle trafficking\, and cytokinesis. Despite its broad biological importance\, the molecular basis of MICAL regulation has remained unclear. In this talk\, I will show how structural biology approaches\, particularly cryo-EM\, combined with biochemical assays\, provide mechanistic insight into MICAL autoinhibition and its activation by Rab GTPases.
URL:https://www.biomed.cas.cz/event/seminar-karolina-kowalska/
LOCATION:Posluchárna 0.195 / Lecture room 0.195
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20260428T100000
DTEND;TZID=Europe/Prague:20260428T113000
DTSTAMP:20260429T082302
CREATED:20260416T061641Z
LAST-MODIFIED:20260416T061941Z
UID:2524-1777370400-1777375800@www.biomed.cas.cz
SUMMARY:Lecture Jonathan W. Yewdell
DESCRIPTION:„How MHC I Peptides Are Generated for Viral and Cancer Immunosurveillance“ \nThe talk focuses on peptide generation from DRiPs (defective ribosomal products)\, ribosomal generated polypeptides that don’t achieve folded stable forms and are proteolytically converted into peptides presented by MHC I molecules for CD8+ T cell immunosurveillance. Influenza A virus DRiPs will occupy center stage. I will discuss dozens of novel influenza virus gene products we discovered in characterizing DRiPs. These include PB1-F2\, the granddaddy of flu alternative reading frame proteins\, UFOs generated from host mRNA start codons\, and most recently\, numerous open reading frames encoded by the negative strand. The talk will conclude with a brief discussion of DRiPs and cancer\, and the contribution of “immunoribosomes“ (subsets of ribosomes) to the cancer immuopeptidome.
URL:https://www.biomed.cas.cz/event/lecture-jonathan-w-yewdell/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20260429T150000
DTEND;TZID=Europe/Prague:20260429T160000
DTSTAMP:20260429T082302
CREATED:20260422T074033Z
LAST-MODIFIED:20260422T074033Z
UID:2526-1777474800-1777478400@www.biomed.cas.cz
SUMMARY:Seminář Joe Howard
DESCRIPTION:“How molecular motors drive the motility of cilia and flagella” \nCilia and flagella are thin\, rod-like organelles whose snake-like beating patterns drive cells through fluids and move fluids across cellular surfaces. They play essential roles in locomotion\, sensory reception\, and signaling. The core structure within the cilium\, known as the axoneme\, consists of nine pairs of doublet microtubules\, a central pair of single microtubules\, and a myriad of other proteins\, including the axonemal dynein motor proteins\, which generate the shear forces that slide adjacent doublets. A key question is how dynein activity is coordinated to produce the characteristic sinusoidal beating patterns. We are addressing this question through reconstitution and modeling\, leveraging the genetics of the unicellular alga Chlamydomonas reinhardtii.
URL:https://www.biomed.cas.cz/event/seminar-joe-howard/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20260504T150000
DTEND;TZID=Europe/Prague:20260504T163000
DTSTAMP:20260429T082302
CREATED:20260428T063031Z
LAST-MODIFIED:20260428T063031Z
UID:2529-1777906800-1777912200@www.biomed.cas.cz
SUMMARY:Methodological Seminar BIOCEV-Krč - Campus Animal Facility
DESCRIPTION:Dear all\, \nwe would like to invite you to the seminar as part of the „BIOCEV-Krč  Methodological Seminar“: \nTopic: „CAMPUS ANIMAL FACILITY“ \nSeminar program: \nAnimal Facility FGÚ: Martin Blažka\nAnimal Facility MBÚ: Alexandra Bartelik / Martin Schwarzer\nAnimal Facility ÚŽFG: Jiří Klíma\nAnimal Facility ÚEM: Andrej Litvinec\nAnimal Facility ÚMG: Libor Kopkan / Jan Honetschläger \nThe Animal facility methodological seminar will include a series of presentations by representatives of individual institutions located on the campus. Each institution will briefly present its local or detached animal facility and the services it provides.
URL:https://www.biomed.cas.cz/event/methodological-seminar-biocev-krc-campus-animal-facility/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260519
DTEND;VALUE=DATE:20260522
DTSTAMP:20260429T082302
CREATED:20260316T081510Z
LAST-MODIFIED:20260316T081510Z
UID:2504-1779148800-1779407999@www.biomed.cas.cz
SUMMARY:AI-based Segmentation and Tracking
DESCRIPTION:Learn practical workflows for image segmentation\, cell tracking\, and denoising using modern deep-learning tools (StarDist\, Cellpose\, Omnipose\, Noise2Void\, DeepImageJ\, TrackMate\, Delta2\, ZeroCostDL4MIc\, Zeiss arivis Cloud). \nMore information & registration:\nhttps://course.img.cas.cz/aist/ \nRegistration deadline: May 4 \nBest regards\,\nMartin Čapek\, Michaela Blažíková\, Jan Valečka and Pavel Krist (Zeiss)
URL:https://www.biomed.cas.cz/event/ai-based-segmentation-and-tracking-2/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260608
DTEND;VALUE=DATE:20260611
DTSTAMP:20260429T082302
CREATED:20260316T081803Z
LAST-MODIFIED:20260316T081803Z
UID:2507-1780876800-1781135999@www.biomed.cas.cz
SUMMARY:Super-Resolution in Light Microscopy - practical course
DESCRIPTION:Dear colleagues\, \n  \nwe would like to announce the upcoming practical course Super-Resolution in Light Microscopy (SLM 2026)\, which will take place June 8–10\, 2026 at the Institute of Molecular Genetics of the Czech Academy of Sciences in Prague. \n  \nSome of you may know our EMBO Practical Course on Super-Resolution Microscopy\, which we bi-annually organize at IMG. The SLM course is a complementary event focused primarily on extended hands-on training\, allowing participants to spend more time working directly with the methods and data processing workflows. \n  \nThe three-day course combines short theoretical introductions with practical sessions in small groups. Participants will work with several super-resolution approaches including SIM\, SMLM\, STED and optical reassignment methods – Airyscan and SoRa. \n  \nThe practical sessions are organized in collaboration with the Microscopy unit at the Institute of Experimental Medicine (IEM CAS). \n  \nThe course is open to an international audience and the number of participants is limited to 15 to ensure an intensive training format. \n  \nMore information\, programme and registration details are available here: \nhttps://course.img.cas.cz/slm/ \n  \nRegistration deadline: May 5\, 2026 \n  \nPlease feel free to share this announcement with colleagues who might be interested. \n  \n  \nBest regards\, \n  \nIvan Novotny & Michaela Blazikova \n  \n  \n  \n\n\n\n\n\n\nIvan Novotny\, Ph.D. | Light Microscopy Core Facility\n\n\n+420 296 44 3192\, 3168\n\n\n+420 777 270 279\n\n\nivan.novotny@img.cas.cz \n\n\nwww.img.cas.cz
URL:https://www.biomed.cas.cz/event/super-resolution-in-light-microscopy-practical-course/
LOCATION:IMG
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