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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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X-Robots-Tag:noindex
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BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
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END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T223000
DTSTAMP:20260427T023313
CREATED:20240917T085823Z
LAST-MODIFIED:20240917T085823Z
UID:2146-1727460000-1727476200@www.biomed.cas.cz
SUMMARY:Researchers’ Night 2024 at the IEM CAS
DESCRIPTION:The mysterious world of experimental (bio)medicine\nAs night falls\, our laboratories become a dark and magical place where the challenges of biomedicine become a reality. The darkness that surrounds the building creates a unique atmosphere. The light of microscopes shines through the darkness and reveals the secrets of life at the molecular and cellular level. Every click of the pipette\, every flash of fluorescence and every record of information brings our scientists closer to their desired goal of discovering new diagnostic and therapeutic procedures that can change patients‘ lives worldwide. \nCome and experience this feeling in person and visit selected experimental (bio)medicine laboratories. We look forward to welcoming you! \nProgramme\nMore information can be found on the official website (only available in Czech).
URL:https://www.biomed.cas.cz/event/researchers-night-2024-at-the-iem-cas/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T220000
DTSTAMP:20260427T023313
CREATED:20240924T130636Z
LAST-MODIFIED:20240924T131704Z
UID:2163-1727460000-1727474400@www.biomed.cas.cz
SUMMARY:Noc vědců
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/noc-vedcu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T130000
DTEND;TZID=Europe/Prague:20240924T140000
DTSTAMP:20260427T023313
CREATED:20240917T082830Z
LAST-MODIFIED:20240917T082922Z
UID:2124-1727182800-1727186400@www.biomed.cas.cz
SUMMARY:IEM CAS μLecture: Two-photon microscopy
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nThe topic of the September seminar will be two-photon microscopy. This technique is especially suitable for the imaging of processes in vivo. We will explain the two-photon microscopy principle\, look at the advantages and disadvantages of this technique and what experiments it can be used for. \nThe seminar will take place on Tuesday 24. 9. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration is not required\, but we will be happy if you can let us know if you plan to come (in person or via email iva.svecova@iem.cas.cz).
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclecture-two-photon-microscopy/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T090000
DTEND;TZID=Europe/Prague:20240927T170000
DTSTAMP:20260427T023313
CREATED:20240823T063438Z
LAST-MODIFIED:20240823T063721Z
UID:1222-1727168400-1727456400@www.biomed.cas.cz
SUMMARY:Holotomography Workshop - TOMOCUBE HT-X1
DESCRIPTION:Dear Colleagues\, \nHolotomography is an advanced imaging technique that uses a specialized microscope to capture high-resolution images of biological structures such as bacteria\, cells\, intracellular structures\, or even entire organoids without the need for staining. This method allows for the acquisition of quantitative data\, including dry mass measurements and various other parameters. \nIf you have ever considered exploring quantitative holotomography microscopy techniques or quantitative phase microscopy\, this is an event you should not miss. \nThis workshop is designed for potential users and is fully dedicated to practically introducing holotomography as a quantitative microscopic technique. The method will be demonstrated through hands-on experience with the TOMOCUBE HT-X1 system. \nThe first half-day will take place a series of theoretical lectures\, followed by three days fully dedicated to hands-on sessions. During these sessions\, you will learn how to set up acquisitions\, perform AI-boosted image segmentation\, and analyze quantitative imaging data. \nLed by one of Tomocube’s most advanced application specialists\, Bruno Combettes\, this workshop offers an excellent opportunity to discuss your experimental ideas and design with an expert in the method and system. It is also a unique chance to test your experimental design and ideas on the system\, with expert guidance. \nThis event also provides an opportunity to gain valuable contacts for your future research work… \nFor any questions\, please contact: ivan.novotny@img.cas.cz.  \n 
URL:https://www.biomed.cas.cz/event/holotomography-workshop-tomocube-ht-x1/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240923T143000
DTEND;TZID=Europe/Prague:20240923T163000
DTSTAMP:20260427T023313
CREATED:20240913T073932Z
LAST-MODIFIED:20240913T073932Z
UID:1973-1727101800-1727109000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - PhDr. Pavel Baran\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je PhDr. Pavel Baran\, CSc.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v pondělí 23. 9. 2024 od 14:30 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-phdr-pavel-baran-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240917
DTEND;VALUE=DATE:20240919
DTSTAMP:20260427T023313
CREATED:20240827T104940Z
LAST-MODIFIED:20240827T104940Z
UID:1225-1726531200-1726703999@www.biomed.cas.cz
SUMMARY:6th CCP Phenogenomics Conference
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/6th-ccp-phenogenomics-conference/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240916T080000
DTEND;TZID=Europe/Prague:20240920T170000
DTSTAMP:20260427T023313
CREATED:20240917T084359Z
LAST-MODIFIED:20240917T084531Z
UID:2142-1726473600-1726851600@www.biomed.cas.cz
SUMMARY:IEM CAS Advanced Course on Preclinical Imaging
DESCRIPTION:Basic information\nThe course aims to teach multimodal preclinical imaging techniques\, including in vivo two-photon microscopy\, in vivo multi-photon-based label-free techniques (SHG\, THG\, CARS)\, and magnetic resonance imaging (MRI) of small rodents. Participants will acquire theoretical knowledge and practical skills in various neuroimaging techniques\, with a focus on intravital multi-photon microscopy and MRI principles. Emphasizing the importance of animal models in physiological research\, the course guides participants through the entire process of conducting preclinical bioimaging experiments. It includes a detailed pipeline for analyzing brain tumour structures and functional parameters\, covering cranial window surgery\, two-photon microscopy usage\, perfusion MRI and subsequent image analysis. Additionally\, the workshop addresses the challenges in using animal models for research and provides access to field experts. \nIntended audience\nThe course is designed for researchers (PhD candidates\, Postdocs\, Principal Investigators\, etc.) with a serious interest in integrating in vivo imaging into their projects. \nMethods\nTwo-photon fluorescent microscopy (functional calcium/voltage imaging\, structural imaging)\, second harmonic generation (SHG)\, third harmonic generation (THG)\, coherent anti-Stokes Raman spectroscopy (CARS)\, high field magnetic resonance perfusion imaging (MRI)\, fluorescence lifetime imaging microscopy (FLIM) \nRegistration and more information can be found on our website.
URL:https://www.biomed.cas.cz/event/iem-cas-advanced-course-on-preclinical-imaging/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240912T140000
DTEND;TZID=Europe/Prague:20240912T150000
DTSTAMP:20260427T023313
CREATED:20240903T124147Z
LAST-MODIFIED:20240903T125118Z
UID:1696-1726149600-1726153200@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 09/2024
DESCRIPTION:The DNA single-strand break repair capacity of the mammalian oocytes and embryos \nLecturer: Nataliia Dudko\, MSc. / Department of Cell Nucleus Plasticity \nAnnotation: The number of de novo mutations in mammalian oocytes and preimplantation embryos is substantially lower than in somatic cells\, but the reasons for this phenomenon are unknown. In our study we focus on minor DNA lesions repaired via BER\, as they are a common source of de novo mutations. We found that the abundance of BER proteins may not be the most critical factor in granting high genomic stability\, and other factors such as chromatin landscape should be considered. \nThe seminar will take place on 12. 9. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-09-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240910T140000
DTEND;TZID=Europe/Prague:20240910T153000
DTSTAMP:20260427T023313
CREATED:20240904T065930Z
LAST-MODIFIED:20240904T065930Z
UID:1701-1725976800-1725982200@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR pro funkční období 2025–2029 - prof. RNDr. David Honys\, Ph.D.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024. \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. David Honys\, Ph.D.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v úterý 10. 9. 2024 od 14:00 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-pro-funkcni-obdobi-2025-2029-prof-rndr-david-honys-ph-d/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240718T150000
DTEND;TZID=Europe/Prague:20240718T163000
DTSTAMP:20260427T023313
CREATED:20240917T083049Z
LAST-MODIFIED:20240917T083057Z
UID:2135-1721314800-1721320200@www.biomed.cas.cz
SUMMARY:IEM CAS Distinguished Guest Seminar Series – Prof. Kai Liu
DESCRIPTION:Lecturer: Prof. Kai Liu / Division of Life Science\, Hong Kong University of Science and Technology \nThe seminar will take place on 18. 07. 2024 from 15:00 in the Turquoise Auditorium of the IEM CAS. \nIntroduction: \nProf. Kai Liu received his Bachelor degree from School of Life Sciences at Peking University in 1998\, and received his Ph.D. from Rutgers University at New Brunswick in 2006. Then he did his postdoc research at Children’s Hospital Boston/Harvard Medical School. He joined Division of Life Science at HKUST as Assistant Professor in 2011\, and is currently Cheng Associate Professor of Science. His research interest focuses on the intrinsic mechanisms regulating axonal regeneration and functional repair after central nervous system injuries.
URL:https://www.biomed.cas.cz/event/iem-cas-distinguished-guest-seminar-series-prof-kai-liu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240718T140000
DTEND;TZID=Europe/Prague:20240718T150000
DTSTAMP:20260427T023313
CREATED:20240917T083319Z
LAST-MODIFIED:20240917T083319Z
UID:2137-1721311200-1721314800@www.biomed.cas.cz
SUMMARY:IEM CAS Distinguished Guest Seminar Series – Cian O'Connor
DESCRIPTION:Lecturer: Cian O’Connor\, PhD. / Tissue engineering research group\, University of Medicine and Health Sciences Dublin \nThe seminar will take place on 18. 07. 2024 from 14:00 in the Turquoise Auditorium of the IEM CAS. \nIntroduction: \nCian O’Connor is a postdoctoral researcher in the Tissue engineering research group led by Prof. Fergal O’Brien\, RCSI & physiology graduate from Trinity College Dublin with an interest in cellular neuroscience and biomaterials. His interest lies in studying glial cells and technological advancements associated with therapeutic treatments particularly via stem cell culture\, development of scaffold implants\, the use of non-viral gene delivery and electroconductive materials. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-distinguished-guest-seminar-series-cian-oconnor/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240626T160000
DTEND;TZID=Europe/Prague:20240626T170000
DTSTAMP:20260427T023313
CREATED:20240612T073038Z
LAST-MODIFIED:20240612T081932Z
UID:932-1719417600-1719421200@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dirk Schübeler
DESCRIPTION:“Finding your place: Transcription factors as sensors and modifiers of chromatin” \nTranscription factors only bind a minority of their motifs in large mammalian genomes. One likely explanation is that many motifs are not accessible for binding due to the action of chromatin and DNA methylation. We are using mammalian stem cell models and their differentiation combined with genomics to understand this important interplay between gene regulation\, chromatin structure and DNA methylation. We study the dynamics of the epigenome and test regulatory models in cellular models by genetic perturbation and genome editing approaches. \nI will discuss our recent efforts in understanding how the sensitivity to DNA methylation and nucleosomes can limit transcription factor binding in the context of the cell and how TFs rely on specific chromatin remodelers for access to their binding sites.
URL:https://www.biomed.cas.cz/event/seminar-prof-dirk-schubeler/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240625T130000
DTEND;TZID=Europe/Prague:20240625T140000
DTSTAMP:20260427T023313
CREATED:20240917T083708Z
LAST-MODIFIED:20240917T083708Z
UID:2140-1719320400-1719324000@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures: Checklists for Publishing Images and Introduction to Image Archives
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers‘ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers‘ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThanks to speedy technological developments\, microscopy images document a significant part of scientific discoveries in this data-intensive era. It is becoming increasingly important to ensure that images are presented in a transparent and reproducible manner. However\, there are only a few guidelines available for publishing terabytes to petabytes of image data\, while research funding agencies require data to be published in open repositories. The objective of this seminar is to provide an overview of the key aspects of data publication\, with a particular focus on image data. In addition\, the seminar will offer a brief introduction to repositories and other relevant resources. \nThe seminar will take place on 25. 6. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come.
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclectures-checklists-for-publishing-images-and-introduction-to-image-archives/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240620T100000
DTEND;TZID=Europe/Prague:20240620T113000
DTSTAMP:20260427T023313
CREATED:20240605T102859Z
LAST-MODIFIED:20240605T102859Z
UID:927-1718877600-1718883000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR pro funkční období 2025–2029 - Ing. Jiří Plešek\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR\nprof. RNDr. Evě Zažímalové\, CSc. Volba kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024. \n\n\n\nJedním z kandidátů na předsedu AV ČR je Ing. Jiří Plešek\, CSc.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-pro-funkcni-obdobi-2025-2029-ing-jiri-plesek-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240619T150000
DTEND;TZID=Europe/Prague:20240619T160000
DTSTAMP:20260427T023313
CREATED:20240611T060610Z
LAST-MODIFIED:20240611T060610Z
UID:930-1718809200-1718812800@www.biomed.cas.cz
SUMMARY:Seminář Josef Novák\, Ph.D.
DESCRIPTION:“Switch of ADP/ATP translocase isoforms in cellular senescence and malignancy” \nFour isoforms of human ATD/ADP translocators (ANTs) have poorly understood functional differences. Due to their high sequence similarity\, antibody-based detection of these proteins is challenging. We\, therefore\, developed a sensitive proteomic method for detecting ATD/ADP translocator isoforms and their relative ratio. Using this technique\, we observed a switch of ANT isoforms during senescence establishment associated with changes in cellular energy metabolism. The switch of ANT protein isoforms was not correlated with the change of ANT transcripts. Similarly\, we found a non-correlation of ANT transcripts with corresponding proteins in patients‘ glioblastoma and lung cancer samples. We concluded that protein levels of ANT isoforms are regulated on multiple levels and are tightly linked to mitochondria biogenesis.
URL:https://www.biomed.cas.cz/event/seminar-josef-novak-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240617T163000
DTEND;TZID=Europe/Prague:20240617T173000
DTSTAMP:20260427T023313
CREATED:20240509T101609Z
LAST-MODIFIED:20240509T101609Z
UID:907-1718641800-1718645400@www.biomed.cas.cz
SUMMARY:Lecture "Obesity cannot be cured\, but increasingly better treated"
DESCRIPTION:Prof. Matthias Blüher\, Director of the Helmholtz Institute for Metabolism\, Obesity and Vasculature research at the Helmholtz Center Munich and the University of Leipzig\, Germany
URL:https://www.biomed.cas.cz/event/lecture-obesity-cannot-be-cured-but-increasingly-better-treated/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T150000
DTEND;TZID=Europe/Prague:20240612T160000
DTSTAMP:20260427T023313
CREATED:20240603T095411Z
LAST-MODIFIED:20240603T095411Z
UID:924-1718204400-1718208000@www.biomed.cas.cz
SUMMARY:Seminář Jiří Březina\, M.Sc.
DESCRIPTION:“How antigens get distributed in the thymus” \nThe presentation of self-antigens in the thymus by medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) is crucial for the establishment of central tolerance. While mTECs produce and present self-antigens in an autonomous manner\, DCs acquire them from mTECs by cooperative antigen transfer (CAT). Although CAT represents a key process of central tolerance\, molecular determinants which define CAT’s effectivity as well as the the capacity of DCs to subsequently present highjacked antigens are largely unknown. To reveal the nature of these determinants\, we compared the transcriptomes of CAT-experienced and inexperienced DCs via scRNAseq. In this seminar\, we will focus on one such a determinant of CAT\, gene product encoding the tight junction protein\, CLAUDIN 1. A series of experiments demonstrated  that CLAUDIN 1 is a regulatory molecule which coordinates CAT and T cell selection processes. The comprehension of these processes will aid in the resolution of the current controversy concerning the role of DCs in central tolerance.
URL:https://www.biomed.cas.cz/event/seminar-jiri-brezina-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T130000
DTEND;TZID=Europe/Prague:20240612T140000
DTSTAMP:20260427T023313
CREATED:20240523T224952Z
LAST-MODIFIED:20240917T083407Z
UID:919-1718197200-1718200800@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures Seminar Series: Digital Image Basics
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThe seminar aims to provide participants with the basic knowledge and skills to work with graphics and digital images. The participants will be introduced to key concepts and techniques. For example\, they will learn how information is stored in a digital image or what bit depth is. Understanding these principles is essential for the proper processing of microscopic data. \nThe seminar will take place on 12.6.2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come. \nLecturer\nJan Setnička
URL:https://www.biomed.cas.cz/event/919/
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240612
DTEND;VALUE=DATE:20240615
DTSTAMP:20260427T023313
CREATED:20240507T075917Z
LAST-MODIFIED:20240507T075917Z
UID:893-1718150400-1718409599@www.biomed.cas.cz
SUMMARY:Practical course SUPER-RESOLUTION IN LIGHT MICROSCOPY
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/practical-course-super-resolution-in-light-microscopy/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240606T140000
DTEND;TZID=Europe/Prague:20240606T150000
DTSTAMP:20260427T023313
CREATED:20240523T221435Z
LAST-MODIFIED:20240523T223848Z
UID:917-1717682400-1717686000@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 06/2024
DESCRIPTION:Open Access Publishing & Green Open Access\nLecturer: Arzuv Caryjeva\, Ph.D. / Data Manager / Director’s Secretariat \nAnnotation: The Open Science requirements of project funders and available options and tools to satisfy these requirements will be introduced. Mainly\, Open access publishing and the green route to ensure open access to Scientific articles will be discussed. Moreover\, there will be an introduction to the Institutional data repository and how researchers can use it. This seminar is particularly important for lab leaders and grant holders. \nThe seminar will take place on 6. 6. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-06-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240605T150000
DTEND;TZID=Europe/Prague:20240605T160000
DTSTAMP:20260427T023313
CREATED:20240528T080600Z
LAST-MODIFIED:20240528T080600Z
UID:922-1717599600-1717603200@www.biomed.cas.cz
SUMMARY:Seminář Subhadip Chakraborty\, M.Sc.
DESCRIPTION:“Understanding the mechanochemical transitions that underlie early embryo development” \nDuring embryogenesis a single fertilized oocyte develops into an adult organism via tightly controlled patterns of cell division\, cell polarization and cell movements. These mechanical processes depend on the actomyosin cortex\, a thin 2D layer that resides underneath the plasma membrane. Importantly\, for normal development the actomyosin cortex in rapidly dividing embryonic cells needs to transition between contractile and non-contractile phases. Surprisingly little is known about how these mechanical transitions are regulated in a developing embryo. To understand mechanical transitions during embryogenesis\, I use C. elegans early embryos as a model\, and perform quantitative live imaging of the actomyosin cortex as it transitions between contractile and non-contractile phases. In the IMG seminar I will present my recent results in which we demonstrate how two major signaling cascades\, Cdc42 and RhoA\, affect distinct mechanical phases and the transitions between them.
URL:https://www.biomed.cas.cz/event/seminar-subhadip-chakraborty-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240603T150000
DTEND;TZID=Europe/Prague:20240603T160000
DTSTAMP:20260427T023313
CREATED:20240509T101513Z
LAST-MODIFIED:20240509T101513Z
UID:905-1717426800-1717430400@www.biomed.cas.cz
SUMMARY:Lecture "How are the epilepsy molecular clocks ticking?"
DESCRIPTION:Cristina Reschke\, RCSI University of Medicine and Health Sciences\, School of Pharmacy and Biomolecular Sciences\, Dublin\, Ireland
URL:https://www.biomed.cas.cz/event/lecture-how-are-the-epilepsy-molecular-clocks-ticking-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240529T150000
DTEND;TZID=Europe/Prague:20240529T160000
DTSTAMP:20260427T023313
CREATED:20240513T113146Z
LAST-MODIFIED:20240513T113146Z
UID:911-1716994800-1716998400@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dominique Bonnet
DESCRIPTION:“Dissecting the cross-talk between normal\, leukaemic stem cells and the bone marrow microenvironment” \nHaematopoietic stem cells (HSC) sustain the life-long maintenance of mature blood cells. Over the last decade progress has been made in our understanding of the contribution of the different stroma cells in the regulation of normal HSCs. Our current knowledge is predominantly derived from mouse studies. In humans\, the cellular and molecular composition of the bone marrow (BM) niche\, its functional organisation remains largely unknown. In recent years\, deregulation of the BM microenvironment has emerged to be an important factor in the development of myeloid malignancies. Indeed\, like normal HSC\, leukaemic stem cells (LSCs) remain dependent on signals from the BM niche for survival and proliferation\, and niche factors serves as a sanctuary for their chemoresistance. Thus\, targeting BM niche factors represents a promising avenue for therapeutic interventions. Determining the niche associated alterations in the composition/ organisation along with dissecting the interactome of LSCs and their niche is thus fundamental\, which will ultimately enable us to understand the mechanism of leukaemia initiation\, evolution and resistance. \nI will summarise some of the recent published data from the lab\, showing the alterations of endothelial cells by AML as well as described the development of our new humanised scaffold system that is allowing us to better study the cross-talk between normal and malignant HSPCs and their bone marrow niche in a human/human context. I will show the utility of this model to study MDS and their dependence to the human niche components. Lastly\, I will also discuss new un/published data on the effect of pre-leukaemic mutation on haematopoieisis.
URL:https://www.biomed.cas.cz/event/seminar-prof-dominique-bonnet/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240527T150000
DTEND;TZID=Europe/Prague:20240527T160000
DTSTAMP:20260427T023313
CREATED:20240516T085615Z
LAST-MODIFIED:20240516T085741Z
UID:913-1716822000-1716825600@www.biomed.cas.cz
SUMMARY:BioCEV-Krč Methodological Seminar
DESCRIPTION:BioCEV-Krč Methodological Seminar\nTopic: Campus Animal Facility \n27. 5. 2024\, start: 15:00 \nvenue: Milan Hašek lecture hall\, IMG CAS \nThe Animal facility methodological seminar will include a series of presentations by representatives of individual institutions located on the campus. Each institution will briefly present its local or detached animal facility and the services it provides
URL:https://www.biomed.cas.cz/event/biocev-krc-methodological-seminar-2/
LOCATION:IMG
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240522T150000
DTEND;TZID=Europe/Prague:20240522T160000
DTSTAMP:20260427T023313
CREATED:20240513T113032Z
LAST-MODIFIED:20240513T113032Z
UID:909-1716390000-1716393600@www.biomed.cas.cz
SUMMARY:Seminář Vadym Sulimenko\, Ph.D.
DESCRIPTION:“Differential roles of GIT1 and GIT2 adaptor proteins in regulating microtubule nucleation in glioblastoma cells” \nMicrotubules play a critical role in cell division and migration\, impacting the viability and invasiveness of malignant tumors. Although the reorganization of highly dynamic microtubules is central to these processes\, the precise mechanism underlying microtubule involvement in glioblastoma cell motility remains poorly understood. G protein-coupled receptor kinase-interacting proteins (GITs) are GTPase-activating proteins (GAPs) for ADP-ribosylation factor (Arf) small GTPases. GITs are structurally conserved multidomain scaffold/adaptor proteins that link Arf GTPases to other intracellular signaling events. Here we show that the signalling proteins GIT1 and GIT2 form complexes with γ-Tubulin ring complexes (γTuRCs)\, associate with centrosomes and differentially regulate microtubule nucleation and cell migration in glioblastoma cells.
URL:https://www.biomed.cas.cz/event/seminar-vadym-sulimenko-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240522
DTEND;VALUE=DATE:20240525
DTSTAMP:20260427T023313
CREATED:20240409T092424Z
LAST-MODIFIED:20240409T092424Z
UID:871-1716336000-1716595199@www.biomed.cas.cz
SUMMARY:IEM CAS Entry Level Super-Resolution Microscopy
DESCRIPTION:Basic Information\nThe course covers theoretical and practical aspects of an “entry-level” super-resolution imaging methods based on the principle of Optical-Photon-Reassignment available in our facility at confocal microscopes Zeiss LSM880\nwith AiryScan and Olympus SpinSR10 with OSR. \nWhat is meant by “Entry-Level Super-Resolution Microscopy”? It is a group of methods that improve resolution by a factor of ~2 over diffraction-limited imaging and are very easy to use. While these methods cannot offer the resolution improvement of factor 5x-10x like STED or STROM/PALM\, they are fast\, easy to operate and require no special sample preparation or extra skills. They are also very suitable for live cell imaging. \n\nDuration: 3 days\nLanguage: English\nLocation: IEM library\, microscope rooms\n\nRegistration form and more information can be found on our website.
URL:https://www.biomed.cas.cz/event/iem-cas-entry-level-super-resolution-microscopy/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240520T150000
DTEND;TZID=Europe/Prague:20240520T160000
DTSTAMP:20260427T023313
CREATED:20240509T101413Z
LAST-MODIFIED:20240509T101413Z
UID:903-1716217200-1716220800@www.biomed.cas.cz
SUMMARY:Lecture "Single-particle tracking of neurotransmitter receptors as a window on synaptic organization and function"
DESCRIPTION:RNDr. Martin Zápotocký\, Ph.D.\, Laboratory of Computational Neuroscience\, IPHYS
URL:https://www.biomed.cas.cz/event/lecture-single-particle-tracking-of-neurotransmitter-receptors-as-a-window-on-synaptic-organization-and-function/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240515T150000
DTEND;TZID=Europe/Prague:20240515T160000
DTSTAMP:20260427T023313
CREATED:20240506T070531Z
LAST-MODIFIED:20240506T070531Z
UID:888-1715785200-1715788800@www.biomed.cas.cz
SUMMARY:Seminář Milan Reiniš\, Ph.D.
DESCRIPTION:“Targeting the STAT3 signaling pathway in cancer and senescence” \nSTAT3 signaling pathway plays important roles in many cellular processes\, such as cell differentiation\, carcinogenesis\, cellular senescence or regulation of the immune responses. The STAT3 molecule thus represents an attractive therapeutic target. However\, its druggability is still questionable. We have tested a number of small molecules designed to inhibit STAT3 phosphorylation for their inhibitory capabilities and impacts on the tumor cell growth. Importantly\, we have documented that selected compounds with limited cytotoxicity were able to inhibit secretion of immunosuppressive cytokines by senescent cells. These results suggest that the STAT3 inhibitors could serve as senomodulatory agents.
URL:https://www.biomed.cas.cz/event/seminar-milan-reinis-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240514T083000
DTEND;TZID=Europe/Prague:20240514T163000
DTSTAMP:20260427T023313
CREATED:20240507T075424Z
LAST-MODIFIED:20240507T075424Z
UID:891-1715675400-1715704200@www.biomed.cas.cz
SUMMARY:3rd 10x Genomics Experience Meeting 2024
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/3rd-10x-genomics-experience-meeting-2024/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240513T150000
DTEND;TZID=Europe/Prague:20240513T160000
DTSTAMP:20260427T023313
CREATED:20240509T101313Z
LAST-MODIFIED:20240509T101313Z
UID:901-1715612400-1715616000@www.biomed.cas.cz
SUMMARY:Lectures of Laboratory of Developmental Cardiology
DESCRIPTION:Vevo 3100: The Short Story of a High-tech Upgrade \nJaroslav Hrdlička\, Laboratory of Developmental Cardiology\, IPHYS \n  \nCardioprotection: the role of HIF-1α and mitochondria \nPetra Alánová\, Laboratory of Developmental Cardiology\, IPHYS
URL:https://www.biomed.cas.cz/event/lectures-of-laboratory-of-developmental-cardiology/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
END:VCALENDAR