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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
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END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240423T140000
DTEND;TZID=Europe/Prague:20240423T150000
DTSTAMP:20260426T235222
CREATED:20240115T114856Z
LAST-MODIFIED:20240320T090026Z
UID:764-1713880800-1713884400@www.biomed.cas.cz
SUMMARY:Lecture "Epoxylipids from biological actions to therapies for cardiovascular\, kidney\, and metabolic diseases"
DESCRIPTION:Prof. John D. Imig\, University of Arkansas for Medical Sciences\, USA
URL:https://www.biomed.cas.cz/event/lecture-epoxylipids-from-biological-actions-to-therapies-for-cardiovascular-kidney-and-metabolic-diseases/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240417T150000
DTEND;TZID=Europe/Prague:20240417T160000
DTSTAMP:20260426T235222
CREATED:20240410T072013Z
LAST-MODIFIED:20240410T072013Z
UID:876-1713366000-1713369600@www.biomed.cas.cz
SUMMARY:Seminář Kristýna Hrychová\, M.Sc.
DESCRIPTION:“Chromatin ADP-ribosylation in neurodegenerative disease” \nADP-ribosylation is a common protein post-translational modification that regulates numerous cellular processes\, including transcription\, cell proliferation and differentiation\, immune and stress responses\, aging\, and cell death. One of its most extensively studied roles is in DNA damage response and subsequent DNA repair. Moreover\, deregulation of ADP-ribose metabolism is linked to neurological and neurodevelopmental disorders. Interestingly\, our recent work reveals that serine ADP-ribosylation is largely dispensable for DNA repair. We propose that deregulated serine ADP-ribosylation might instead lead to alterations in other histone modifications\, changes in chromatin remodeling and gene expression\, and consequently could contribute to the development of neurological diseases.
URL:https://www.biomed.cas.cz/event/seminar-kristyna-hrychova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240415T150000
DTEND;TZID=Europe/Prague:20240415T160000
DTSTAMP:20260426T235222
CREATED:20240320T085807Z
LAST-MODIFIED:20240320T085807Z
UID:827-1713193200-1713196800@www.biomed.cas.cz
SUMMARY:Lecture "How Foxk1 and Foxk2 Regulate Aerobic Glycolysis – Implications for Systemic Energy Homeostasis and Type 2 Diabetes"
DESCRIPTION:Prof. Sven Enerbäck\, Department of Medical Biochemistry and Cell Biology\, Institute of Biomedicine\, University of Gothenburg\, Sweden.
URL:https://www.biomed.cas.cz/event/lecture-how-foxk1-and-foxk2-regulate-aerobic-glycolysis-implications-for-systemic-energy-homeostasis-and-type-2-diabetes/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240410T150000
DTEND;TZID=Europe/Prague:20240410T160000
DTSTAMP:20260426T235222
CREATED:20240320T082325Z
LAST-MODIFIED:20240320T082325Z
UID:818-1712761200-1712764800@www.biomed.cas.cz
SUMMARY:Seminář Takashi Akera\, Ph.D.
DESCRIPTION:“The impact of genetic cheating on mammalian reproduction and speciation” \n Selfish DNA violate Mendel’s Law of Segregation by biased segregation to the egg cell. This genetic cheating\, meiotic drive\, is a widespread phenomenon across eukaryotes with associated fitness costs such as fertility issues. I will discuss our recent work on the cell biological mechanism of meiotic drive and how it can impact mammalian reproduction and speciation.
URL:https://www.biomed.cas.cz/event/seminar-takashi-akera-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240408T150000
DTEND;TZID=Europe/Prague:20240408T160000
DTSTAMP:20260426T235222
CREATED:20240320T085651Z
LAST-MODIFIED:20240320T085651Z
UID:825-1712588400-1712592000@www.biomed.cas.cz
SUMMARY:Lecture "Cancer metabolism"
DESCRIPTION:RNDr. Katarína Smolková\, Ph.D.\, Laboratory of Mitochondrial Physiology\, IPHYS \n 
URL:https://www.biomed.cas.cz/event/lecture-cancer-metabolism/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240404T140000
DTEND;TZID=Europe/Prague:20240404T143000
DTSTAMP:20260426T235222
CREATED:20240207T113012Z
LAST-MODIFIED:20240402T080600Z
UID:784-1712239200-1712241000@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 04/2024
DESCRIPTION:Maternal diet quality and health status of newborns\nLecturer: Mgr. Jitka Pavlíková\, Ph.D. / Department of Toxicology a Molecular Epidemiology \nAnnotation: Persistent organic pollutants are compounds of mostly anthropogenic origin that persist in the environment for a long time\, become part of food chains\, and some of them accumulate in living organisms. These substances are being monitored for their adverse effects on organisms\, and the use of some of them has already been banned or at least significantly restricted. In our study\, we analyzed possible associations between the health status of newborns (birth weight\, oxidative damage levels) and maternal diet. We obtained information about diet quantity and quality from the maternal diet records and determined the concentrations of 67 different persistent organic pollutants in the collected samples. \nThe seminar will take place on 4. 4. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-04-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240403T150000
DTEND;TZID=Europe/Prague:20240403T160000
DTSTAMP:20260426T235222
CREATED:20240320T082234Z
LAST-MODIFIED:20240320T082234Z
UID:816-1712156400-1712160000@www.biomed.cas.cz
SUMMARY:Seminář Jose Ordovas-Montanes\, M.Sc.\, Ph.D.
DESCRIPTION:“Single-cell to tissue-scale memory of infection and inflammation” \nThe role of epithelial and stromal cells in driving inflammation\, together with immune cells\, is being increasingly appreciated. However\, we currently lack tissue-scale frameworks to define and test how inflammation collectively impacts epithelial\, stromal\, and immune cells. This poses a fundamental challenge for understanding the cellular mechanisms that drive or sustain health and disease within\, and across\, barriers such as the skin\, airway\, and intestine. Our lab is addressing this challenge by quantifying and controlling how inflammation changes the ecology of barrier tissues. Our central hypothesis is that inflammation is distributed and stored in multiple cell types\, with the capacity to form tissue-level collective cellular networks. Starting from our human single-cell RNA-sequencing data collected from infectious and inflammatory diseases\, we are developing quantitative approaches to define how static cellular ecosystems are arranged in barrier tissues. These studies are informing time-series modeling of murine inflammatory models focused on Type 1\, 2 and 17 inflammation to understand how the same pressure applied to epithelial\, stromal\, and immune cell subsets shifts functional states and interactions in distinct barrier tissues. We anticipate to identify the gradual inflammatory transitions which maintain essential tissue functionality and critical “tipping points” in tissue state that compromise barrier functions.
URL:https://www.biomed.cas.cz/event/seminar-jose-ordovas-montanes-m-sc-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240327T150000
DTEND;TZID=Europe/Prague:20240327T160000
DTSTAMP:20260426T235222
CREATED:20240318T080719Z
LAST-MODIFIED:20240318T080719Z
UID:807-1711551600-1711555200@www.biomed.cas.cz
SUMMARY:Seminář Veronika Zimolová\, M.Sc.
DESCRIPTION:“Janus Kinase 2 (JAK2) mutations: implications for blood diseases” \nThe project aims to elucidate the impact of the germline Jak2 R1063H variant on myeloproliferative disorders and its potential implication in myeloid malignancy predisposition. Utilizing a mouse model harboring the Jak2 R1063H mutation\, we observed higher mortality rate\, elevated D-dimer levels indicative of thrombotic events\, and increased platelets counts. Furthermore\, metabolic profiling revealed alterations in platelet bioenergetics and gene expression patterns associated with fatty acid metabolism. Additionally\, we showed aberrations in hematopoietic stem cell functionality\, manifesting as a skewed myeloid progenitor cell expansion and bone marrow remodeling. These findings collectively suggest that Jak2 R1063H variant represents risk factor in the pathogenesis of myeloid cell transformation.
URL:https://www.biomed.cas.cz/event/seminar-veronika-zimolova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240326T130000
DTEND;TZID=Europe/Prague:20240326T140000
DTSTAMP:20260426T235222
CREATED:20240409T093101Z
LAST-MODIFIED:20240409T121238Z
UID:873-1711458000-1711461600@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures Seminar Series: Cameras and Detectors
DESCRIPTION:μLectures is a new monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, will focus on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThe second session will focus on cameras and detectors. We will talk about the difference between cameras and detectors\, and what parameters are important for which kind of experiments.\n \nThe seminar will take place on 26. 3. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link (open in a new window). \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come. \nLecturer\nŠtěpán Kortus\, PhD.
URL:https://www.biomed.cas.cz/event/%ce%bclectures-cameras-and-detectors/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240325T150000
DTEND;TZID=Europe/Prague:20240325T160000
DTSTAMP:20260426T235222
CREATED:20240320T085512Z
LAST-MODIFIED:20240320T085512Z
UID:823-1711378800-1711382400@www.biomed.cas.cz
SUMMARY:Lecture "Hemodynamic mechanisms initiating salt-sensitive hypertension: Prevention options"
DESCRIPTION:Ing. Michal Pravenec\, DrSc.\, Laboratory of Genetics of Model Diseases\, IPHYS
URL:https://www.biomed.cas.cz/event/lecture-hemodynamic-mechanisms-initiating-salt-sensitive-hypertension-prevention-options/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240320T150000
DTEND;TZID=Europe/Prague:20240320T160000
DTSTAMP:20260426T235222
CREATED:20240306T080948Z
LAST-MODIFIED:20240306T080948Z
UID:805-1710946800-1710950400@www.biomed.cas.cz
SUMMARY:Seminář  Zuzana Outlá\, M.Sc.
DESCRIPTION:„Targeting plectin-mediated cytoskeletal crosstalk in hepatocellular carcinoma“ \nAnotace: The study’s findings indicate that the elevation of plectin in tumor hepatocytes is associated with the progression of hepatocellular carcinoma (HCC). This progression can be inhibited through genetic or pharmacological targeting of plectin. The oncogenic and invasive potentials of HCC cells are attenuated through plectin ablation\, suggesting that plectin contributes to HCC’s metastatic capacity. These results identify plectin as a potential therapeutic target in HCC.
URL:https://www.biomed.cas.cz/event/seminar-zuzana-outla-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240313T150000
DTEND;TZID=Europe/Prague:20240313T160000
DTSTAMP:20260426T235222
CREATED:20240306T080743Z
LAST-MODIFIED:20240306T080743Z
UID:803-1710342000-1710345600@www.biomed.cas.cz
SUMMARY:Seminář Imtissal Krayem\, Ph.D.
DESCRIPTION:“Transmembrane adaptor protein OPAL1 regulates leukocyte hematopoiesis and thymus development” \nExpression of transmembrane adaptor protein Outcome predictor of acute leukemia 1 (OPAL1)\, has been linked to the ETV6-RUNX1 translocation and favorable prognosis in childhood leukemia. Our research also suggests that it has an important role in leukocyte development. We show that in mice with germline deletion of OPAL1\, hematopoiesis is dysregulated early on\, affecting mainly hematopoietic stem cells and early progenitors. Dysregulations in this compartment also contribute to more efficient engraftment of OPAL1-deficient cells following hematopoietic stem and progenitor cell transplantations. In addition\, the thymi of OPAL1-deficient mice are enlarged\, housing increased numbers of thymocytes across all subsets. This phenomenon may be attributed to the elevated generation of MPP4/LMPP progenitors in the bone marrow\, which subsequently give rise to thymus-seeding progenitors. In summary\, WBP1L emerges as a key player in leukocyte homeostasis\, maintaining leukocyte numbers during steady-state conditions and after bone marrow transplantation.
URL:https://www.biomed.cas.cz/event/seminar-imtissal-krayem-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240307T140000
DTEND;TZID=Europe/Prague:20240307T150000
DTSTAMP:20260426T235222
CREATED:20240122T091559Z
LAST-MODIFIED:20240207T112651Z
UID:773-1709820000-1709823600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 03/2024
DESCRIPTION:Subpopulations of NG2 glia in the adult mouse brain after focal cerebral ischemia.\nLecturer: Mgr. Tomáš Knotek / Department of Cellular Neurophysiology \nAnnotation: Glia expressing NG2 antigen are known predominantly as precursors of oligodendrocytes. However\, their differentiation potential in tissue affected by ischemic injury has not yet been fully explored. To further our understanding of these cells\, we employed single-cell RNA sequencing\, immunohistochemical staining\, RT-qPCR\, and patch-clamp technique on NG2-expressing cells in healthy tissue and in tissue affected by focal cerebral ischemia (FCI). Single-cell RNA sequencing data revealed that NG2 glia form distinct subpopulations\, some of which can be ascribed to the proliferation of NG2 glia and their progression in the oligodendrocyte lineage. However\, we also observed previously described astrocyte-like NG2 glia that appeared both in healthy and ischemic tissue. Interestingly\, this subpopulation also shared properties with neural progenitor cells. Expression of genes linked to neurogenesis was confirmed by immunohistochemical staining and changed at different time points after FCI. Of note\, 28 days after the stroke\, we observed NG2-expressing cells positive for NeuN. Together\, these results provide new insight into the plasticity of NG2 glia following ischemic injury. \nThe seminar will take place on 7. 3. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-03-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240306T150000
DTEND;TZID=Europe/Prague:20240306T160000
DTSTAMP:20260426T235222
CREATED:20240228T082050Z
LAST-MODIFIED:20240228T082050Z
UID:800-1709737200-1709740800@www.biomed.cas.cz
SUMMARY:Seminář Simona Mikula Mršťáková\, M.Sc.
DESCRIPTION:“Role of pax6 genes in the eye during embryonal development of medaka” \nPax6 is remarkably conserved across a wide range of species\, from flies to humans\, signifying its fundamental role in the regulatory network governing eye formation. In this presentation\, we will delve into the functions of three pax6 genes – Pax6.1\, Pax6.2\, and Pax6.3 – and their specific contributions to eye development during the embryonic stages of the Japanese medaka fish (Oryzias latipes). We will explore how these genes orchestrate the complex process of eye formation\, underscoring their importance in developmental biology and evolutionary studies.
URL:https://www.biomed.cas.cz/event/seminar-simona-mikula-mrstakova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240304T150000
DTEND;TZID=Europe/Prague:20240304T160000
DTSTAMP:20260426T235222
CREATED:20240115T114730Z
LAST-MODIFIED:20240115T114730Z
UID:762-1709564400-1709568000@www.biomed.cas.cz
SUMMARY:Lecture "AMPA glutamate receptor signaling – auxiliary subunits and beyond"
DESCRIPTION:Dr. Ingo Greger\, Neurobiology Division MRC Laboratory of Molecular Biology\, Cambridge\, UK
URL:https://www.biomed.cas.cz/event/lecture-ampa-glutamate-receptor-signaling-auxiliary-subunits-and-beyond/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240228T150000
DTEND;TZID=Europe/Prague:20240228T160000
DTSTAMP:20260426T235222
CREATED:20240228T081937Z
LAST-MODIFIED:20240228T081937Z
UID:798-1709132400-1709136000@www.biomed.cas.cz
SUMMARY:Seminář Prasoon Kumar Thakur\, M.Sc.
DESCRIPTION:“Splicing in the world of marine diplonemids” \nRecent surveys of marine biodiversity have revealed the abundance and diversity of planktonic diplonemids. By sequencing the genomes and transcriptomes of six marine diplonemids and performing comprehensive splice site analyses\, we identified numerous non-canonical introns and mapped their common features\, shedding light on the evolution of RNA splicing in these abundant unicellular organisms.
URL:https://www.biomed.cas.cz/event/seminar-prasoon-kumar-thakur-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240227T130000
DTEND;TZID=Europe/Prague:20240227T140000
DTSTAMP:20260426T235222
CREATED:20240213T101009Z
LAST-MODIFIED:20240213T101009Z
UID:790-1709038800-1709042400@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures: Microscope objectives
DESCRIPTION:μLectures is a new\, monthly seminar series designed to enhance researchers’ understanding of the fundamental workings and principles of microscopy. Each session\, lasting 30 minutes\, will focus on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them better overview of the options available and enabling them to improve their experimental design\, and more effectively identify and resolve potential issues.  \nAnnotation\nThe first session will focus on objectives. It will introduce different types of objectives and their relevant parameters\, explore the interaction between immersion and medium/fixation methods\, and discuss how objective selection can impact image quality.  \nThe seminar will take place on 27. 2. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link (opens in new window). \nIt will be held in English. \nRegistration\nRegistration is not required\, but if you are interested\, you can let us know (in person or on iva.svecova@iem.cas.cz) to give us an idea about how many people are planning to come. \nLecturer\nIva Švecová
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclectures-microscope-objectives/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240222T093000
DTEND;TZID=Europe/Prague:20240222T150000
DTSTAMP:20260426T235222
CREATED:20240214T082352Z
LAST-MODIFIED:20240214T082352Z
UID:796-1708594200-1708614000@www.biomed.cas.cz
SUMMARY:Den fyziologie a medicíny pro vysokoškoláky
DESCRIPTION:Studujete vysokou školu přírodovědeckého nebo medicínského zaměření? Připravili jsme pro vás speciální den otevřených dveří s nabídkou zajímavých témat pro vaši bakalářskou či magisterskou práci i témata pro studium PhD. Vědci z FGÚ vás s nimi seznámí v dopoledním bloku (prezenční i online formou) a odpoledne budete mít možnost nahlédnout přímo do jejich laboratoří. Celý program je v angličtině. \nPřihlašování  a program: https://www.fgu.cas.cz/articles/1114-program-den-fyziologie-a-mediciny-pro-vysokoskolaky-2024 \n 
URL:https://www.biomed.cas.cz/event/den-fyziologie-a-mediciny-pro-vysokoskolaky/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240221T150000
DTEND;TZID=Europe/Prague:20240221T160000
DTSTAMP:20260426T235222
CREATED:20240213T114522Z
LAST-MODIFIED:20240213T114522Z
UID:792-1708527600-1708531200@www.biomed.cas.cz
SUMMARY:Seminář Ing. Eliška Gáliková
DESCRIPTION:“Knocking out spo11 in chicken arrests meiosis but does not prevent further development of germ cells” \nKnockout of the mouse spo11 prevents double-strand breaks and formation of synaptonemal complex during meiosis. As a result\, the development of spermatocytes is arrested at zygotene and the arrested cells undergo apoptosis. Not so in the chicken. Here\, although we also observe arrest of meiosis and impaired fertility\, diploid spermatocytes and oocytes continue to develop with interesting biological consequences.
URL:https://www.biomed.cas.cz/event/seminar-ing-eliska-galikova/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240220T140000
DTEND;TZID=Europe/Prague:20240220T150000
DTSTAMP:20260426T235222
CREATED:20240214T082128Z
LAST-MODIFIED:20240214T082128Z
UID:794-1708437600-1708441200@www.biomed.cas.cz
SUMMARY:Hodnocení výzkumu v Akademii věd ČR
DESCRIPTION:Přednášející:  prof. Ing. Jiří Homola\, CSc.\, DSc. \nOrganizace přednášky byla projednána a schválena na schůzi Rady areálu dne 15.1.2024. \nVzhledem k projednávanému tématu a v návaznosti na administraci procesu hodnocení\, se přednáška bude konat pouze v českém jazyce.
URL:https://www.biomed.cas.cz/event/hodnoceni-vyzkumu-v-akademii-ved-cr/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240219T150000
DTEND;TZID=Europe/Prague:20240219T160000
DTSTAMP:20260426T235222
CREATED:20240212T120433Z
LAST-MODIFIED:20240212T120433Z
UID:788-1708354800-1708358400@www.biomed.cas.cz
SUMMARY:Lecture "Microtubule associated proteins and their regulation - between brain development and disease"
DESCRIPTION:Martin Balaštík\, Ph.D.\, Laboratory of Molecular Neurobiology\, IPHYS
URL:https://www.biomed.cas.cz/event/lecture-microtubule-associated-proteins-and-their-regulation-between-brain-development-and-disease/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240214T150000
DTEND;TZID=Europe/Prague:20240214T160000
DTSTAMP:20260426T235222
CREATED:20240130T112256Z
LAST-MODIFIED:20240130T112256Z
UID:778-1707922800-1707926400@www.biomed.cas.cz
SUMMARY:Seminář Miroslav Stoyanov\, M.Sc.
DESCRIPTION:“PPM1D activity promotes genome instability and cellular transformation” \nProtein phosphatase magnesium dependent 1 (PPM1D) is a negative regulator of the tumour suppressor p53 and is implicated in termination of DNA damage response. Increased PPM1D activity allows proliferation in the presence of DNA breaks caused by ionizing radiation or replication stress induced by expression of active RAS oncogene. Active PPM1D promotes cell growth in the soft agar and formation of tumours in nude mice confirming the oncogenic potential of PPM1D.
URL:https://www.biomed.cas.cz/event/seminar-miroslav-stoyanov-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240207T150000
DTEND;TZID=Europe/Prague:20240207T160000
DTSTAMP:20260426T235222
CREATED:20240123T082320Z
LAST-MODIFIED:20240206T070143Z
UID:776-1707318000-1707321600@www.biomed.cas.cz
SUMMARY:Seminář Dr. rer. nat. Leoš Shivaya Valášek\, DSc.
DESCRIPTION:“Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough” \nImagine a gene is a sentence starting with a capital letter and ending with a period\, and a genome as a book telling an entire story. In some protozoans\, extra periods infiltrated their sentences\, replacing specific letters of arbitrary words (namely E and W). As a r.sult\, r.aders (ribosom.s) are confus.d about .here these sentenc.s really .nd\, and the story b.comes disjoint.d. We described how these protozoans handled this mystery\, shedding a new light on (non)universality of the genetic code.
URL:https://www.biomed.cas.cz/event/seminar-prof-dr-reinhard-luhrmann/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240201T140000
DTEND;TZID=Europe/Prague:20240201T150000
DTSTAMP:20260426T235222
CREATED:20240122T091345Z
LAST-MODIFIED:20240122T091504Z
UID:771-1706796000-1706799600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 02/2024
DESCRIPTION:The role of miR-20a in the injured CNS\nLecturer: Mgr. Ivan Arzhanov / Department of Neuroregeneration \nAnnotation: Spinal cord injury (SCI) involves damage to any part of the spinal cord\, leading to nervous cell death and disruption of conduction pathways. This damage results in the loss of motor and sensory function below the injury site\, potentially causing paralysis and\, in severe cases\, complete paralysis. Following SCI\, a myriad of genes undergo dysregulation\, accompanied by alterations in the expression of microRNAs (miRNAs). MiRNAs\, small non-coding RNA molecules\, play a pivotal regulatory role in various biological processes by interfering with mRNA. In our experiments\, the expression of miR-20a was significantly upregulated for at least one week post-trauma. MiR-20a targets numerous genes\, hindering the regenerative process of nervous tissue. However\, inhibiting miR-20a decreases pro-apoptotic gene expression while facilitating the expression of anti-apoptotic genes\, thereby diminishing neural cell death after injury. During this seminar\, we will summarise the data regarding changes in mRNAs\, miRNAs\, and protein expression following SCI. Subsequently\, we will specifically focus on miR-20a and its role in basic cellular processes following SCI. \nThe seminar will take place on 1. 2. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-02-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240131T150000
DTEND;TZID=Europe/Prague:20240131T160000
DTSTAMP:20260426T235222
CREATED:20240117T065534Z
LAST-MODIFIED:20240117T065534Z
UID:767-1706713200-1706716800@www.biomed.cas.cz
SUMMARY:Seminář Maria Kuzmina\, M.Sc.
DESCRIPTION:“HSCs in inflammation: go extramedullary or go home” \nHematopoietic stem cells (HSCs) are a rare cell type residing in the bone marrow and giving rise to all hematopoietic cells. Despite their quiescence\, HSCs respond to extracellular signals which regulate their fate. In this presentation\, we will determine how of chronic inflammation affects HSC location and function.
URL:https://www.biomed.cas.cz/event/seminar-maria-kuzmina-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240129T150000
DTEND;TZID=Europe/Prague:20240129T160000
DTSTAMP:20260426T235222
CREATED:20240115T114433Z
LAST-MODIFIED:20240115T114433Z
UID:759-1706540400-1706544000@www.biomed.cas.cz
SUMMARY:BioCEV-Krč Methodological Seminar
DESCRIPTION:Topic: Spatial metabolomics \nProgram: https://www.fgu.cas.cz/significant/event/495 \n 
URL:https://www.biomed.cas.cz/event/biocev-krc-methodological-seminar/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240124T150000
DTEND;TZID=Europe/Prague:20240124T160000
DTSTAMP:20260426T235222
CREATED:20240111T072555Z
LAST-MODIFIED:20240111T072555Z
UID:755-1706108400-1706112000@www.biomed.cas.cz
SUMMARY:Seminář Martin Estermann\, Ph.D.
DESCRIPTION:“The cell biology and molecular genetics of avian gonadal development” \nI am interested in investigating the regulatory mechanisms governing sex differentiation in avian species\, with a specific focus on utilizing the chicken as a model organism. In the course of my presentation\, I will explore the cellular foundations and molecular components dictating the development of ovarian and testicular fate in avian species. Employing comparative approaches\, I will scrutinize the distinctive attributes of the ZZ and ZW chromosome sex determination system\, elucidating its role in cell-autonomous sex determination. Lastly\, I will share my recent postdoctoral findings particularly the metabolic regulation of sex differentiation.
URL:https://www.biomed.cas.cz/event/seminar-martin-estermann-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240118T140000
DTEND;TZID=Europe/Prague:20240118T150000
DTSTAMP:20260426T235222
CREATED:20231208T124440Z
LAST-MODIFIED:20240122T091240Z
UID:741-1705586400-1705590000@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series (replacement date from 10/2023)
DESCRIPTION:Lsp1 partially substitutes Pil1 function in eisosome assembly under stress conditions\nLecturer: Ing. Petra Veselá\, Ph.D. / Department of Functional Organisation of Biomembranes \nAnnotation: Eisosomes are large hemitubular structures that underlie the invaginated microdomains in the plasma membrane of various organisms and take part in the cellular stress response. In the yeast Saccharomyces cerevisiae\, they are organised by BAR-domain containing proteins Pil1 and Lsp1. While under normal laboratory conditions\, deletion of the PIL1 gene results in the inability of cells to assemble eisosomes\, deletion of LSP1 shows no apparent phenotype. We show that under stress conditions\, Lsp1 takes over the Pil1 function and forms eisosomes even in the absence of Pil1. \nThe seminar will take place on 18. 1. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/institutional-seminar-series-alternative-date-from-10-2023/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240117T150000
DTEND;TZID=Europe/Prague:20240117T160000
DTSTAMP:20260426T235222
CREATED:20240108T074737Z
LAST-MODIFIED:20240108T074823Z
UID:752-1705503600-1705507200@www.biomed.cas.cz
SUMMARY:Seminář Viktor Bugajev\, Ph.D.
DESCRIPTION:“The novel sphingolipid synthesis regulators in cell life” \nSphingolipids are bioactive lipids and critical structural components of cell membranes. Regulation of their de novo synthesis is critical for normal mammalian development and physiology. Although the ORMDL family has been identified as the gatekeeper of the serine palmitoyl transferase (SPT) activity\, our new data suggest that other components are also involved. We will present our results on new regulators of the SPT complex based on their interaction with members of the ORMDL family using genetic\, immunogenetic and mass spectrometry approaches. Our data indicate that SPT regulatory circuits are more complex than previously thought.
URL:https://www.biomed.cas.cz/event/seminar-viktor-bugajev-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240104T140000
DTEND;TZID=Europe/Prague:20240104T150000
DTSTAMP:20260426T235222
CREATED:20231208T123949Z
LAST-MODIFIED:20231208T123949Z
UID:739-1704376800-1704380400@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 01/2024
DESCRIPTION:Improvement of healing of bone defects by new approaches of regenerative medicine\nLecturer: Mgr. Eva Šebová / Department of Tissue Engineering \nAnnotation: The PLA and PCL block copolymer combined with hydroxyapatite nanoparticles is a promising material for bone tissue engineering. We expect a high ability to seamlessly interact with bone cells and promote bone growth\, which is at the core of our research. By exploring electrospun nanofibers\, we aim to uncover the potential of copolymer with hydroxyapatite in new bone healing strategies\, offering promising avenues for more effective and efficient bone regeneration therapies. \nThe seminar will take place on 4. 1. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-01-2024/
END:VEVENT
END:VCALENDAR