Akce

Cameron S.Metcalf, Dept.Pharmacology, University of Utah, Salt Lake City, USA venue: Conference room of Laboratory of Biomathematics in Krč areal (Vídeńská 1083)          

Vevo 3100: The Short Story of a High-tech Upgrade Jaroslav Hrdlička, Laboratory of Developmental Cardiology, IPHYS   Cardioprotection: the role of HIF-1α and mitochondria Petra Alánová, Laboratory of Developmental Cardiology, IPHYS

“Targeting the STAT3 signaling pathway in cancer and senescence” STAT3 signaling pathway plays important roles in many cellular processes, such as cell differentiation, carcinogenesis, cellular senescence or regulation of the immune responses. The STAT3 molecule thus represents an attractive therapeutic target. However, its druggability is still questionable. We have tested a number of small molecules…
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RNDr. Martin Zápotocký, Ph.D., Laboratory of Computational Neuroscience, IPHYS

Basic Information The course covers theoretical and practical aspects of an “entry-level” super-resolution imaging methods based on the principle of Optical-Photon-Reassignment available in our facility at confocal microscopes Zeiss LSM880 with AiryScan and Olympus SpinSR10 with OSR. What is meant by “Entry-Level Super-Resolution Microscopy”? It is a group of methods that improve resolution by a factor of ~2…
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“Differential roles of GIT1 and GIT2 adaptor proteins in regulating microtubule nucleation in glioblastoma cells” Microtubules play a critical role in cell division and migration, impacting the viability and invasiveness of malignant tumors. Although the reorganization of highly dynamic microtubules is central to these processes, the precise mechanism underlying microtubule involvement in glioblastoma cell motility…
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BioCEV-Krč Methodological Seminar Topic: Campus Animal Facility 27. 5. 2024, start: 15:00 venue: Milan Hašek lecture hall, IMG CAS The Animal facility methodological seminar will include a series of presentations by representatives of individual institutions located on the campus. Each institution will briefly present its local or detached animal facility and the services it provides

“Dissecting the cross-talk between normal, leukaemic stem cells and the bone marrow microenvironment” Haematopoietic stem cells (HSC) sustain the life-long maintenance of mature blood cells. Over the last decade progress has been made in our understanding of the contribution of the different stroma cells in the regulation of normal HSCs. Our current knowledge is predominantly…
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Cristina Reschke, RCSI University of Medicine and Health Sciences, School of Pharmacy and Biomolecular Sciences, Dublin, Ireland

“Understanding the mechanochemical transitions that underlie early embryo development” During embryogenesis a single fertilized oocyte develops into an adult organism via tightly controlled patterns of cell division, cell polarization and cell movements. These mechanical processes depend on the actomyosin cortex, a thin 2D layer that resides underneath the plasma membrane. Importantly, for normal development the…
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Open Access Publishing & Green Open Access Lecturer: Arzuv Caryjeva, Ph.D. / Data Manager / Director's Secretariat Annotation: The Open Science requirements of project funders and available options and tools to satisfy these requirements will be introduced. Mainly, Open access publishing and the green route to ensure open access to Scientific articles will be discussed.…
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