BEGIN:VCALENDAR
VERSION:2.0
PRODID:-// - ECPv6.6.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241204T150000
DTEND;TZID=Europe/Prague:20241204T160000
DTSTAMP:20260426T170924
CREATED:20241126T132009Z
LAST-MODIFIED:20241126T132009Z
UID:2263-1733324400-1733328000@www.biomed.cas.cz
SUMMARY:Seminář Marie Zelená\, M.Sc.
DESCRIPTION:“Every stick has two ends – Using high resolution imaging to characterize both ends of the eukaryotic flagellum” \nThe eukaryotic flagellum is important for cell motility. The microtubule-based axoneme generating the flagellar beating has been extensively studied. However\, additional structures are associated with the proximal and distal end of the flagellum\, with their composition and processes of their formation being poorly understood. \nTo gain an insigth into these structures we have studied them in the protozoan parasite Trypanosoma brucei\, which is experimentally highly tractable. First\, we focused on the flagellar pocket around the proximal end of the flagellum\, which is the exclusive site for endocytosis and exocytosis of the parasite. Using expansion microscopy we were able to define discrete stages of the flagellar pocket division and formation of the flagellar pocket collar\, which seals the pocket. Second\, we took advantage of our knowledge of the flagellum distal-end proteome and combined it with expansion microscopy and cryo-electron tomography to characterize the enigmatic microtubule plugs at the distal end of the flagellum. \nOur work elucidates aspects of the flagellar biology of an important parasite. Moreover\, given the conserved nature of the organelle\, our results have also implications for flagella across eukaryotes.
URL:https://www.biomed.cas.cz/event/seminar-marie-zelena-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241203
DTEND;VALUE=DATE:20241206
DTSTAMP:20260426T170924
CREATED:20241101T112749Z
LAST-MODIFIED:20241101T112841Z
UID:2242-1733184000-1733443199@www.biomed.cas.cz
SUMMARY:Live Cell Imaging Course 2024
DESCRIPTION:The course is very practically-oriented\, theoretical lectures are followed by 6 hours of hands-on session every day in small groups. You will learn widefield\, confocal\, and advanced methods including super-resolution\, photomanipulation\, and FLIM. You will have a chance to work on high-end microscopes and compare wide variety of approaches and instrumentation. \nFor detailed program and overview of taught methods and microscopes please check course webpage: https://course.img.cas.cz/lci/ \nLooking forward to seeing you! \nJan Valečka and Helena Chmelová
URL:https://www.biomed.cas.cz/event/live-cell-imaging-course-2024/
LOCATION:IMG
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241127T150000
DTEND;TZID=Europe/Prague:20241127T160000
DTSTAMP:20260426T170924
CREATED:20241118T123730Z
LAST-MODIFIED:20241118T123730Z
UID:2260-1732719600-1732723200@www.biomed.cas.cz
SUMMARY:Seminář Michaela Procházková\, M.Sc.
DESCRIPTION:“CRL4COP1 ubiquitination complex as a balancer of early odontogenesis” \nCullin-RING ubiquitin ligase (CRL) complexes have been heavily studied in connection to cancer progression but there is limited evidence about their physiological roles. One of the exceptions is disruption of limb development by thalidomide induced by inhibition of CRL4 complex via regulation of Fgf8 (Ito et al.\, 2010). Notably\, Fgf8 expressing population is essential also for development of tooth primordia and we found CRL4 genes to be specifically expressed within odontognic epithelium. We further identified COP1 as a substrate binding protein which can bind ETS transcription factors\, downstream targets of Fgf pathway\, and unveiled that conditional deletion of CRL4 genes severly affects size and morphology of molar primordia and future teeth.
URL:https://www.biomed.cas.cz/event/seminar-michaela-prochazkova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241127T080000
DTEND;TZID=Europe/Prague:20241129T170000
DTSTAMP:20260426T170924
CREATED:20240917T090109Z
LAST-MODIFIED:20241014T102557Z
UID:2148-1732694400-1732899600@www.biomed.cas.cz
SUMMARY:IEM CAS Introduction to Programming for Image Processing 2024
DESCRIPTION:Due to reaching capacity for in-person participation\, registration is now only available for online attendance. Thank you for your understanding.  \nBasic information\nThe course is tailored to users already familiar with the basics of image processing. It will be focused on automatization\, high throughput and basic scripting. Course participants will learn how to create and edit macros in ImageJ and how to write more sophisticated scripts for batch processing. Furthermore\, they will learn the basics of image processing in Matlab and Cellpose. \nDuration: 3 days \nLanguage: English \nProgramme\nLocation: Turquoise Auditorium \nSpeakers: Barbora Hyklová\, Štěpán Kortus\, Iva Švecová\, Jakub Zahumenský \nDay 1 / Wednesday / 27. 11. 2024\n\nIntroduction\, macro recording and editing in ImageJ\nWriting a complex macro for batch processing – automatic data import\, cell segmentation\, measurements\, export in organized format\n\nDay 2 / Thursday / 28. 11. 2024\n\nScript automation\, ImageJ customization\nCell segmentation using Cellpose and integration of Cellpose into the workflow\nDemonstration of a complex ImageJ/Cellpose workflow\n\nDay 3 / Friday / 29.11. 2024\n\nOptional: Discussion of individual projects and data analysis questions. \n\nRequirements\nPrior Experience with ImageJ: Participants should have a basic familiarity with ImageJ and its fundamental features. They should be comfortable with tasks like image import\, basic processing (e.g.\, brightness/contrast adjustments)\, and measurements.  \nOwn laptop: Participants are required to bring their own laptop for hands-on exercises. If you do not have access to a laptop\, please inform us in advance\, and we will provide you with one. Prior to the event\, you will receive a list of required software programs to install for the course. \n\n\n\n\n\n\n\n\n\n\nRegistration\nRegistration here: free of charge \n  \n\n\n 
URL:https://www.biomed.cas.cz/event/introduction-to-programming-for-image-processing-2024-preliminary-date/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241126T100000
DTEND;TZID=Europe/Prague:20241126T173000
DTSTAMP:20260426T170924
CREATED:20241115T065915Z
LAST-MODIFIED:20241115T070057Z
UID:2256-1732615200-1732642200@www.biomed.cas.cz
SUMMARY:IEM CAS - BIOCEV Regeneration IV
DESCRIPTION:We are pleased to announce the annual mini-symposium BIOCEV Regeneration IV\, which will be held on November 26th\, 2024\, in BIOCEV Centre\, Vestec. \nBIOCEV Regeneration is an annual open one-day mini-symposium that brings together researchers from different fields of biomedicine\, from regenerative medicine and tissue engineering to cancer research\, drug discovery\, and cryobiology. \nThis year\, the BIOCEV Regeneration IV will focus on the exciting field of cryobiology and cryobanking and highlight its important role in state-of-the-art biomedical research. The mini-symposium is endorsed by the international Society for Low Temperature Biology (SLTB) and will bring together keynote speakers and young researchers from different biomedical disciplines\, employing low temperatures in their research and development. This year we will focus on two major directions of cryobiology: cryotechnologies in clinically-oriented research (ATMP production\, cell and tissue banking for therapy and diagnostics) and biodiversity preservation and regeneration. \nThe mini-symposium will be held in the main conference hall and surrounding spaces of the BIOCEV and broadcast online. \nAlong with several lectures given by our invited speakers\, we encourage early career researchers to contribute to our symposium and share achievements in stem cell research\, tissue engineering\, 3D culture\, cancer research or cryobiology during the poster session. \nThe event is free of charge. More information can be found in the official invitation. \nWe look forward to seeing you. \n  \nRegistration
URL:https://www.biomed.cas.cz/event/iem-cas-biocev-regeneration-iv/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241125T150000
DTEND;TZID=Europe/Prague:20241125T160000
DTSTAMP:20260426T170924
CREATED:20241021T122910Z
LAST-MODIFIED:20241021T122910Z
UID:2215-1732546800-1732550400@www.biomed.cas.cz
SUMMARY:18th BioCEV-Krč Methodological Seminar
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/18th-biocev-krc-methodological-seminar/
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241121T110000
DTEND;TZID=Europe/Prague:20241121T120000
DTSTAMP:20260426T170924
CREATED:20241111T071221Z
LAST-MODIFIED:20241111T071221Z
UID:2253-1732186800-1732190400@www.biomed.cas.cz
SUMMARY:Seminář Matthias G. Fischer
DESCRIPTION:Max Planck Institute for Medical Research\, Heidelberg \n“Viruses of unicellular eukaryotes: A tale of giants and hyperparasites” \nViruses of protists play important roles in ecology and evolution by influencing microbial population dynamics and shaping eukaryotic genomes by endogenization. Of particular interest are complex DNA viruses whose particle and genome sizes overlap with those of bacteria. In this talk\, I will highlight some remarkable properties of these giant viruses and explore their relationship with smaller DNA viruses\, called virophages\, which can parasitize giant viruses and thus act as an antiviral defense system in certain protist species.
URL:https://www.biomed.cas.cz/event/seminar-matthias-g-fischer/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241120T150000
DTEND;TZID=Europe/Prague:20241120T160000
DTSTAMP:20260426T170924
CREATED:20241104T072502Z
LAST-MODIFIED:20241120T070615Z
UID:2249-1732114800-1732118400@www.biomed.cas.cz
SUMMARY:Seminář doc. Mgr. Lumír Krejčí\, Ph.D. - ZRUŠENO
DESCRIPTION:“Homologous Recombination – From Repair of DSBs to Processing Stalled Replication Forks and Human Diseases” \nOur lab focuses on the mechanisms ensuring accurate DNA replication and the role of homologous recombination (HR) in preventing genome instability. We investigate how endogenous hard-to-replicate regions\, G-quadruplexes (G4) and R-loops\, impact replication and contribute to disease development. A key aspect involves studying the formation and regulation of RAD51 filaments during HR. We explore how positive regulators like BRCA2 and RAD51 paralogs promote filament assembly and its stability\, while negative regulators like RECQ5 and RECQ4 helicase help balance replication stress and genome stability.
URL:https://www.biomed.cas.cz/event/seminar-doc-mgr-lumir-krejci-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241119T090000
DTEND;TZID=Europe/Prague:20241119T140000
DTSTAMP:20260426T170924
CREATED:20241101T113131Z
LAST-MODIFIED:20241101T113131Z
UID:2245-1732006800-1732024800@www.biomed.cas.cz
SUMMARY:Den otevřených dveří
DESCRIPTION:Prohlídka laboratoří\, ukázky experimentů v oblasti molekulární genetiky\, imunologie\, buněčné biologie\, virologie\, prohlídka posterů a diskuse k vybraným tématům.
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241118T160000
DTEND;TZID=Europe/Prague:20241118T170000
DTSTAMP:20260426T170924
CREATED:20241021T122808Z
LAST-MODIFIED:20241021T122808Z
UID:2213-1731945600-1731949200@www.biomed.cas.cz
SUMMARY:Lecture „The role of cornichons in the biogenesis and functioning of monovalent-cation transport systems“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-the-role-of-cornichons-in-the-biogenesis-and-functioning-of-monovalent-cation-transport-systems/
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241113T150000
DTEND;TZID=Europe/Prague:20241113T160000
DTSTAMP:20260426T170924
CREATED:20241104T072334Z
LAST-MODIFIED:20241104T072334Z
UID:2247-1731510000-1731513600@www.biomed.cas.cz
SUMMARY:Seminář Aleš Neuwirth\, Ph.D.
DESCRIPTION:“Unravelling autoimmunity in Addison’s disease using a new mouse model” \nAutoimmune Addison’s disease is a disorder targeting steroid-producing cells in the adrenal glands. Due to the lack of suitable animal models\, the immune mechanisms underlying adrenal destruction remain largely unknown. To address this\, we developed the first defined mouse model of experimental autoimmune adrenalitis by immunizing C57BL/6 mice with immunogenic peptides derived from CYP11A1\, a rate-limiting enzyme in steroidogenesis. This model allows us to study the pathogenesis of Addison’s disease and provides a unique opportunity to investigate the fate decisions of self-reactive CD4+ T cells and their clonal lineages in a well-defined autoimmune setting.
URL:https://www.biomed.cas.cz/event/seminar-ales-neuwirth-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241111T150000
DTEND;TZID=Europe/Prague:20241111T160000
DTSTAMP:20260426T170924
CREATED:20241021T122639Z
LAST-MODIFIED:20241021T122639Z
UID:2211-1731337200-1731340800@www.biomed.cas.cz
SUMMARY:Lecture „Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-tissue-specific-sex-dependent-difference-in-the-metabolism-of-fatty-acid-esters-of-hydroxy-fatty-acids/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241107T140000
DTEND;TZID=Europe/Prague:20241107T150000
DTSTAMP:20260426T170924
CREATED:20241014T093123Z
LAST-MODIFIED:20241101T163717Z
UID:2177-1730988000-1730991600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 11/2024
DESCRIPTION:Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation\nLecturer: Satyendra Mondal\, MSc. / Department of Functional Organisation of Biomembranes \nAnnotation: The regulation of eukaryotic gene expression via mRNA degradation is an evolutionarily conserved process\, with the 5′-3′ exoribonuclease 1 (Xrn1) playing a pivotal role. In yeast\, following the depletion of fermentable carbon source\, Xrn1 is sequestered at the plasma membrane-associated protein complex\, the eisosome\, where it becomes inactive. In this study\, we show that the plasma membrane localisation of Xrn1 requires the core eisosome components and identify a putative eisosome-binding domain of Xrn1. Our findings demonstrate that the eisosome binding of Xrn1 is subject to the halting of ongoing glycolytic flux rather than the availability of fermentable carbon sources. Furthermore\, we show that the localisation of the human orthologue of Xrn1 resembles that of its yeast counterpart when expressed in yeast. Our results advance our understanding of the plasma membrane-associated regulation of Xrn1 and indicate that the regulation principle may be evolutionarily conserved from yeast to humans. \nThe seminar will take place on 7. 11. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-11-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241107
DTEND;VALUE=DATE:20241108
DTSTAMP:20260426T170924
CREATED:20241021T122515Z
LAST-MODIFIED:20241021T122515Z
UID:2209-1730937600-1731023999@www.biomed.cas.cz
SUMMARY:Den otevřených dveří - FGÚ
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri-fgu-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241104
DTEND;VALUE=DATE:20241108
DTSTAMP:20260426T170924
CREATED:20241018T065127Z
LAST-MODIFIED:20241101T113003Z
UID:2201-1730678400-1731023999@www.biomed.cas.cz
SUMMARY:3-day course on Single cell analysis - from qPCR to sequencing
DESCRIPTION:This course will provide valuable insights and practical skills in the rapidly evolving field of single cell analyses and spatial transcriptomics. With a maximum of 10 participants\, you’ll receive personalized attention and the opportunity to engage deeply with the subject. \nIf you’re interested in joining us\, please respond via email to sindelka@ibt.cas.cz as soon as possible\, as space is limited. \nWe look forward to an enriching experience together!
URL:https://www.biomed.cas.cz/event/3-day-course-on-single-cell-analysis-from-qpcr-to-sequencing/
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241030T150000
DTEND;TZID=Europe/Prague:20241030T160000
DTSTAMP:20260426T170924
CREATED:20241016T094609Z
LAST-MODIFIED:20241030T074419Z
UID:2198-1730300400-1730304000@www.biomed.cas.cz
SUMMARY:Seminář Martina Zíková\, Ph.D. - ZRUŠENO
DESCRIPTION:“Impact of Medulloblastoma-Derived Extracellular Vesicles on Neural Stem/Progenitor Cells” \nMedulloblastoma is the most common malignant brain tumor in children. Recent advances in understanding its genetic and molecular heterogeneity have uncovered at least four distinct subgroups\, each characterized by unique transcriptional profiles\, DNA alterations and clinical outcomes. Extracellular vesicle secretion has emerged as a critical mediator of communication within the tumor microenvironment. In this presentation\, we will discuss our progress in deciphering the effects of extracellular vesicles derived and purified from medulloblastoma cells on neural stem/progenitor cell gene expressions.
URL:https://www.biomed.cas.cz/event/seminar-martina-zikova-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241023T150000
DTEND;TZID=Europe/Prague:20241023T160000
DTSTAMP:20260426T170924
CREATED:20241016T085332Z
LAST-MODIFIED:20241016T085332Z
UID:2196-1729695600-1729699200@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dr. Daniel Sauter
DESCRIPTION:“Viral Influencers: How endogenous retroviruses regulate innate immunity and senescence” \nThe human genome harbors a significant number of endogenous retroviral elements\, remnants of ancient viral integration events. While often referred to as “genomic fossils“ and “dark matter of the genome” many of these elements function as promoters or enhancers for cellular genes. This presentation will show how a specific subset of endogenous retroviruses is activated during infection\, orchestrating the expression of genes involved antiviral immunity and cell cycle regulation.
URL:https://www.biomed.cas.cz/event/seminar-prof-dr-daniel-sauter/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241022T103000
DTEND;TZID=Europe/Prague:20241022T113000
DTSTAMP:20260426T170924
CREATED:20241014T061308Z
LAST-MODIFIED:20241014T061308Z
UID:2174-1729593000-1729596600@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - prof. RNDr. Libor Grubhoffer\, CSc.\, dr. h. c. mult.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. Libor Grubhoffer\, CSc.\, dr. h. c. mult.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v úterý 22. 10. 2024 od 10:30 hod. v posluchárně Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-prof-rndr-libor-grubhoffer-csc-dr-h-c-mult/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241021T150000
DTEND;TZID=Europe/Prague:20241021T160000
DTSTAMP:20260426T170924
CREATED:20241021T122316Z
LAST-MODIFIED:20241021T122403Z
UID:2206-1729522800-1729526400@www.biomed.cas.cz
SUMMARY:Lecture „Metabolic dysfunction-associated steatotic liver disease: its modeling in mice and the effect of n-3 fatty acids“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-metabolic-dysfunction-associated-steatotic-liver-disease-its-modeling-in-mice-and-the-effect-of-n-3-fatty-acids/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241016T093000
DTEND;TZID=Europe/Prague:20241016T103000
DTSTAMP:20260426T170924
CREATED:20241008T073612Z
LAST-MODIFIED:20241008T073612Z
UID:2172-1729071000-1729074600@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - prof. RNDr. Radomír Pánek\, Ph.D.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. Radomír Pánek\, Ph.D.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání ve středu 16. 10. 2024 od 9:30 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-prof-rndr-radomir-panek-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241011
DTEND;VALUE=DATE:20241012
DTSTAMP:20260426T170924
CREATED:20241001T074244Z
LAST-MODIFIED:20241001T074244Z
UID:2168-1728604800-1728691199@www.biomed.cas.cz
SUMMARY:17th IMG PhD conference
DESCRIPTION:Dear colleagues\, \nWe would like to invite you to the 17th IMG PhD conference that will be on the 11th of October.  \nThis year we will be hosting two international speakers: Mileidys Perez Alea\, who will have a talk about ¨How to build a Start-up¨ and Elodie Chabrol\, who will be talking about the world of ¨Science Communication¨. \nWe are opening the registration for everyone who is interested in attending the sessions we organized. You can find the program as well as information about the conference at the IMG website and the registration link below. \nWe are looking forward to seeing all of you and enjoying with us the up-coming conference. \nBest regards\, \nAnton & Irina
URL:https://www.biomed.cas.cz/event/17th-img-phd-conference/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241009T150000
DTEND;TZID=Europe/Prague:20241009T160000
DTSTAMP:20260426T170924
CREATED:20241001T064659Z
LAST-MODIFIED:20241001T064659Z
UID:2166-1728486000-1728489600@www.biomed.cas.cz
SUMMARY:Seminář Kristína Jamrichová\, M.Sc.
DESCRIPTION:“Investigating the Impact of Cullin-Dependent Degradation on Protein Homeostasis” \nCullin-dependent ligases (CRLs) regulate cellular homeostasis by targeting proteins for degradation. Mutations and alterations in the CRL substrate receptor FBXO38 have been linked to distal muscular atrophy\, chronic obstructive pulmonary disease\, and gender dysphoria. In our previous research\, we demonstrated that FBXO38 controls centromeric chromatin density during spermatogenesis. We will present our progress in deciphering FBXO38 function\, particularly in the context of protein homeostasis and ribosomal activity. \n 
URL:https://www.biomed.cas.cz/event/seminar-kristina-jamrichova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241003T140000
DTEND;TZID=Europe/Prague:20241003T150000
DTSTAMP:20260426T170924
CREATED:20240917T082247Z
LAST-MODIFIED:20240917T082612Z
UID:2110-1727964000-1727967600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 10/2024
DESCRIPTION:Single-particle tracking of NMDA receptors at hippocampal synapses\nLecturer: Mgr. Petra Zahumenská / Department of Neurochemistry \nAnnotation: N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors essential for excitatory neurotransmission. These heterotetrameric complexes consist of two obligatory GluN1 subunits combined with two GluN2 (GluN2A-GluN2D) or GluN3 (GluN3A-GluN3B) subunits. The surface expression and subtype composition of NMDARs are tightly regulated through externalization\, internalization\, and lateral diffusion between synaptic and extrasynaptic regions. \nIn our study\, we utilized the uPAINT (Universal Point Accumulation Imaging in Nanoscale Topography) microscopy technique to examine the surface dynamics of different NMDAR subtypes. uPAINT enables the tracking of individual NMDARs with a high spatial and temporal resolution by labelling them with fluorescent probes. This allows us to observe the distinct patterns of synaptic and extrasynaptic localization of GluN2A- and GluN2B-containing NMDARs in hippocampal neurons. Our approach combines the use of a small anti-GFP nanobody derived from a llama conjugated with an Atto647N fluorophore\, along with the tdTomato-Homer1c marker\, to define synaptic regions. This allows us to gain insights into the mobility and distribution of NMDAR subtypes at the synaptic level. \nThe seminar will take place on 3. 10. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-10-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241002T150000
DTEND;TZID=Europe/Prague:20241002T160000
DTSTAMP:20260426T170924
CREATED:20240919T063219Z
LAST-MODIFIED:20240919T104402Z
UID:2151-1727881200-1727884800@www.biomed.cas.cz
SUMMARY:Seminář Marharyta Klianitskaya\, Ing.
DESCRIPTION:“Human Endogenous Retroviruses: Role in Negative Selection of T cells in the Thymus and Pathogenesis of Psoriasis” \nOur research elucidates the role of human endogenous retroviruses (HERVs) in biological processes related to T cell immunity\, autoimmunity\, and the pathogenesis of psoriasis. HERVs are ancient viral elements integrated into the human genome. While most of these elements are rendered non-functional due to mutations and epigenetic silencing\, some retain the ability to express themselves. Despite their foreign origin\, the expression of these endogenous retroviruses does not typically trigger autoimmune disease. \nThe study employed single-cell RNA sequencing data from thymic tissues\, revealing that a wide range of HERVs is expressed in thymic cells responsible for presenting autoantigens to T cells and for their subsequent negative selection. This suggests that some HERVs may be perceived by the immune system as autoantigens\, and disruptions in the negative selection process could potentially lead to autoimmune diseases. \nPsoriasis is a T cell-mediated chronic inflammatory skin disease that occurs in predisposed individuals carrying specific HLA-C alleles\, which are crucial for presenting small peptides to T cells that survey for non-self peptides. RNA-seq data from psoriasis-affected tissues highlighted a significant correlation between elevated HERV expression and the development of the disease. These findings emphasize the potential role of HERVs in T cell-mediated conditions and offer new insights into the molecular mechanisms underlying psoriasis.
URL:https://www.biomed.cas.cz/event/seminar-marharyta-klianitskaya-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T223000
DTSTAMP:20260426T170924
CREATED:20240917T085823Z
LAST-MODIFIED:20240917T085823Z
UID:2146-1727460000-1727476200@www.biomed.cas.cz
SUMMARY:Researchers’ Night 2024 at the IEM CAS
DESCRIPTION:The mysterious world of experimental (bio)medicine\nAs night falls\, our laboratories become a dark and magical place where the challenges of biomedicine become a reality. The darkness that surrounds the building creates a unique atmosphere. The light of microscopes shines through the darkness and reveals the secrets of life at the molecular and cellular level. Every click of the pipette\, every flash of fluorescence and every record of information brings our scientists closer to their desired goal of discovering new diagnostic and therapeutic procedures that can change patients‘ lives worldwide. \nCome and experience this feeling in person and visit selected experimental (bio)medicine laboratories. We look forward to welcoming you! \nProgramme\nMore information can be found on the official website (only available in Czech).
URL:https://www.biomed.cas.cz/event/researchers-night-2024-at-the-iem-cas/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T220000
DTSTAMP:20260426T170924
CREATED:20240924T130636Z
LAST-MODIFIED:20240924T131704Z
UID:2163-1727460000-1727474400@www.biomed.cas.cz
SUMMARY:Noc vědců
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/noc-vedcu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T130000
DTEND;TZID=Europe/Prague:20240924T140000
DTSTAMP:20260426T170924
CREATED:20240917T082830Z
LAST-MODIFIED:20240917T082922Z
UID:2124-1727182800-1727186400@www.biomed.cas.cz
SUMMARY:IEM CAS μLecture: Two-photon microscopy
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nThe topic of the September seminar will be two-photon microscopy. This technique is especially suitable for the imaging of processes in vivo. We will explain the two-photon microscopy principle\, look at the advantages and disadvantages of this technique and what experiments it can be used for. \nThe seminar will take place on Tuesday 24. 9. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration is not required\, but we will be happy if you can let us know if you plan to come (in person or via email iva.svecova@iem.cas.cz).
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclecture-two-photon-microscopy/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T090000
DTEND;TZID=Europe/Prague:20240927T170000
DTSTAMP:20260426T170924
CREATED:20240823T063438Z
LAST-MODIFIED:20240823T063721Z
UID:1222-1727168400-1727456400@www.biomed.cas.cz
SUMMARY:Holotomography Workshop - TOMOCUBE HT-X1
DESCRIPTION:Dear Colleagues\, \nHolotomography is an advanced imaging technique that uses a specialized microscope to capture high-resolution images of biological structures such as bacteria\, cells\, intracellular structures\, or even entire organoids without the need for staining. This method allows for the acquisition of quantitative data\, including dry mass measurements and various other parameters. \nIf you have ever considered exploring quantitative holotomography microscopy techniques or quantitative phase microscopy\, this is an event you should not miss. \nThis workshop is designed for potential users and is fully dedicated to practically introducing holotomography as a quantitative microscopic technique. The method will be demonstrated through hands-on experience with the TOMOCUBE HT-X1 system. \nThe first half-day will take place a series of theoretical lectures\, followed by three days fully dedicated to hands-on sessions. During these sessions\, you will learn how to set up acquisitions\, perform AI-boosted image segmentation\, and analyze quantitative imaging data. \nLed by one of Tomocube’s most advanced application specialists\, Bruno Combettes\, this workshop offers an excellent opportunity to discuss your experimental ideas and design with an expert in the method and system. It is also a unique chance to test your experimental design and ideas on the system\, with expert guidance. \nThis event also provides an opportunity to gain valuable contacts for your future research work… \nFor any questions\, please contact: ivan.novotny@img.cas.cz.  \n 
URL:https://www.biomed.cas.cz/event/holotomography-workshop-tomocube-ht-x1/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240923T143000
DTEND;TZID=Europe/Prague:20240923T163000
DTSTAMP:20260426T170924
CREATED:20240913T073932Z
LAST-MODIFIED:20240913T073932Z
UID:1973-1727101800-1727109000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - PhDr. Pavel Baran\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je PhDr. Pavel Baran\, CSc.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v pondělí 23. 9. 2024 od 14:30 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-phdr-pavel-baran-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240917
DTEND;VALUE=DATE:20240919
DTSTAMP:20260426T170924
CREATED:20240827T104940Z
LAST-MODIFIED:20240827T104940Z
UID:1225-1726531200-1726703999@www.biomed.cas.cz
SUMMARY:6th CCP Phenogenomics Conference
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/6th-ccp-phenogenomics-conference/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
END:VCALENDAR