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X-ORIGINAL-URL:https://www.biomed.cas.cz
X-WR-CALDESC:Akce na 
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BEGIN:VTIMEZONE
TZID:Europe/Prague
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
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TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241107T140000
DTEND;TZID=Europe/Prague:20241107T150000
DTSTAMP:20260426T160904
CREATED:20241014T093123Z
LAST-MODIFIED:20241101T163717Z
UID:2177-1730988000-1730991600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 11/2024
DESCRIPTION:Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation\nLecturer: Satyendra Mondal\, MSc. / Department of Functional Organisation of Biomembranes \nAnnotation: The regulation of eukaryotic gene expression via mRNA degradation is an evolutionarily conserved process\, with the 5′-3′ exoribonuclease 1 (Xrn1) playing a pivotal role. In yeast\, following the depletion of fermentable carbon source\, Xrn1 is sequestered at the plasma membrane-associated protein complex\, the eisosome\, where it becomes inactive. In this study\, we show that the plasma membrane localisation of Xrn1 requires the core eisosome components and identify a putative eisosome-binding domain of Xrn1. Our findings demonstrate that the eisosome binding of Xrn1 is subject to the halting of ongoing glycolytic flux rather than the availability of fermentable carbon sources. Furthermore\, we show that the localisation of the human orthologue of Xrn1 resembles that of its yeast counterpart when expressed in yeast. Our results advance our understanding of the plasma membrane-associated regulation of Xrn1 and indicate that the regulation principle may be evolutionarily conserved from yeast to humans. \nThe seminar will take place on 7. 11. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-11-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241107
DTEND;VALUE=DATE:20241108
DTSTAMP:20260426T160904
CREATED:20241021T122515Z
LAST-MODIFIED:20241021T122515Z
UID:2209-1730937600-1731023999@www.biomed.cas.cz
SUMMARY:Den otevřených dveří - FGÚ
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/den-otevrenych-dveri-fgu-2/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241104
DTEND;VALUE=DATE:20241108
DTSTAMP:20260426T160904
CREATED:20241018T065127Z
LAST-MODIFIED:20241101T113003Z
UID:2201-1730678400-1731023999@www.biomed.cas.cz
SUMMARY:3-day course on Single cell analysis - from qPCR to sequencing
DESCRIPTION:This course will provide valuable insights and practical skills in the rapidly evolving field of single cell analyses and spatial transcriptomics. With a maximum of 10 participants\, you’ll receive personalized attention and the opportunity to engage deeply with the subject. \nIf you’re interested in joining us\, please respond via email to sindelka@ibt.cas.cz as soon as possible\, as space is limited. \nWe look forward to an enriching experience together!
URL:https://www.biomed.cas.cz/event/3-day-course-on-single-cell-analysis-from-qpcr-to-sequencing/
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241030T150000
DTEND;TZID=Europe/Prague:20241030T160000
DTSTAMP:20260426T160904
CREATED:20241016T094609Z
LAST-MODIFIED:20241030T074419Z
UID:2198-1730300400-1730304000@www.biomed.cas.cz
SUMMARY:Seminář Martina Zíková\, Ph.D. - ZRUŠENO
DESCRIPTION:“Impact of Medulloblastoma-Derived Extracellular Vesicles on Neural Stem/Progenitor Cells” \nMedulloblastoma is the most common malignant brain tumor in children. Recent advances in understanding its genetic and molecular heterogeneity have uncovered at least four distinct subgroups\, each characterized by unique transcriptional profiles\, DNA alterations and clinical outcomes. Extracellular vesicle secretion has emerged as a critical mediator of communication within the tumor microenvironment. In this presentation\, we will discuss our progress in deciphering the effects of extracellular vesicles derived and purified from medulloblastoma cells on neural stem/progenitor cell gene expressions.
URL:https://www.biomed.cas.cz/event/seminar-martina-zikova-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241023T150000
DTEND;TZID=Europe/Prague:20241023T160000
DTSTAMP:20260426T160904
CREATED:20241016T085332Z
LAST-MODIFIED:20241016T085332Z
UID:2196-1729695600-1729699200@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dr. Daniel Sauter
DESCRIPTION:“Viral Influencers: How endogenous retroviruses regulate innate immunity and senescence” \nThe human genome harbors a significant number of endogenous retroviral elements\, remnants of ancient viral integration events. While often referred to as “genomic fossils“ and “dark matter of the genome” many of these elements function as promoters or enhancers for cellular genes. This presentation will show how a specific subset of endogenous retroviruses is activated during infection\, orchestrating the expression of genes involved antiviral immunity and cell cycle regulation.
URL:https://www.biomed.cas.cz/event/seminar-prof-dr-daniel-sauter/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241022T103000
DTEND;TZID=Europe/Prague:20241022T113000
DTSTAMP:20260426T160904
CREATED:20241014T061308Z
LAST-MODIFIED:20241014T061308Z
UID:2174-1729593000-1729596600@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - prof. RNDr. Libor Grubhoffer\, CSc.\, dr. h. c. mult.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. Libor Grubhoffer\, CSc.\, dr. h. c. mult.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v úterý 22. 10. 2024 od 10:30 hod. v posluchárně Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-prof-rndr-libor-grubhoffer-csc-dr-h-c-mult/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241021T150000
DTEND;TZID=Europe/Prague:20241021T160000
DTSTAMP:20260426T160904
CREATED:20241021T122316Z
LAST-MODIFIED:20241021T122403Z
UID:2206-1729522800-1729526400@www.biomed.cas.cz
SUMMARY:Lecture „Metabolic dysfunction-associated steatotic liver disease: its modeling in mice and the effect of n-3 fatty acids“
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/lecture-metabolic-dysfunction-associated-steatotic-liver-disease-its-modeling-in-mice-and-the-effect-of-n-3-fatty-acids/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241016T093000
DTEND;TZID=Europe/Prague:20241016T103000
DTSTAMP:20260426T160904
CREATED:20241008T073612Z
LAST-MODIFIED:20241008T073612Z
UID:2172-1729071000-1729074600@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - prof. RNDr. Radomír Pánek\, Ph.D.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. Radomír Pánek\, Ph.D.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání ve středu 16. 10. 2024 od 9:30 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-prof-rndr-radomir-panek-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20241011
DTEND;VALUE=DATE:20241012
DTSTAMP:20260426T160904
CREATED:20241001T074244Z
LAST-MODIFIED:20241001T074244Z
UID:2168-1728604800-1728691199@www.biomed.cas.cz
SUMMARY:17th IMG PhD conference
DESCRIPTION:Dear colleagues\, \nWe would like to invite you to the 17th IMG PhD conference that will be on the 11th of October.  \nThis year we will be hosting two international speakers: Mileidys Perez Alea\, who will have a talk about ¨How to build a Start-up¨ and Elodie Chabrol\, who will be talking about the world of ¨Science Communication¨. \nWe are opening the registration for everyone who is interested in attending the sessions we organized. You can find the program as well as information about the conference at the IMG website and the registration link below. \nWe are looking forward to seeing all of you and enjoying with us the up-coming conference. \nBest regards\, \nAnton & Irina
URL:https://www.biomed.cas.cz/event/17th-img-phd-conference/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241009T150000
DTEND;TZID=Europe/Prague:20241009T160000
DTSTAMP:20260426T160904
CREATED:20241001T064659Z
LAST-MODIFIED:20241001T064659Z
UID:2166-1728486000-1728489600@www.biomed.cas.cz
SUMMARY:Seminář Kristína Jamrichová\, M.Sc.
DESCRIPTION:“Investigating the Impact of Cullin-Dependent Degradation on Protein Homeostasis” \nCullin-dependent ligases (CRLs) regulate cellular homeostasis by targeting proteins for degradation. Mutations and alterations in the CRL substrate receptor FBXO38 have been linked to distal muscular atrophy\, chronic obstructive pulmonary disease\, and gender dysphoria. In our previous research\, we demonstrated that FBXO38 controls centromeric chromatin density during spermatogenesis. We will present our progress in deciphering FBXO38 function\, particularly in the context of protein homeostasis and ribosomal activity. \n 
URL:https://www.biomed.cas.cz/event/seminar-kristina-jamrichova-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241003T140000
DTEND;TZID=Europe/Prague:20241003T150000
DTSTAMP:20260426T160904
CREATED:20240917T082247Z
LAST-MODIFIED:20240917T082612Z
UID:2110-1727964000-1727967600@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 10/2024
DESCRIPTION:Single-particle tracking of NMDA receptors at hippocampal synapses\nLecturer: Mgr. Petra Zahumenská / Department of Neurochemistry \nAnnotation: N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors essential for excitatory neurotransmission. These heterotetrameric complexes consist of two obligatory GluN1 subunits combined with two GluN2 (GluN2A-GluN2D) or GluN3 (GluN3A-GluN3B) subunits. The surface expression and subtype composition of NMDARs are tightly regulated through externalization\, internalization\, and lateral diffusion between synaptic and extrasynaptic regions. \nIn our study\, we utilized the uPAINT (Universal Point Accumulation Imaging in Nanoscale Topography) microscopy technique to examine the surface dynamics of different NMDAR subtypes. uPAINT enables the tracking of individual NMDARs with a high spatial and temporal resolution by labelling them with fluorescent probes. This allows us to observe the distinct patterns of synaptic and extrasynaptic localization of GluN2A- and GluN2B-containing NMDARs in hippocampal neurons. Our approach combines the use of a small anti-GFP nanobody derived from a llama conjugated with an Atto647N fluorophore\, along with the tdTomato-Homer1c marker\, to define synaptic regions. This allows us to gain insights into the mobility and distribution of NMDAR subtypes at the synaptic level. \nThe seminar will take place on 3. 10. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-10-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20241002T150000
DTEND;TZID=Europe/Prague:20241002T160000
DTSTAMP:20260426T160904
CREATED:20240919T063219Z
LAST-MODIFIED:20240919T104402Z
UID:2151-1727881200-1727884800@www.biomed.cas.cz
SUMMARY:Seminář Marharyta Klianitskaya\, Ing.
DESCRIPTION:“Human Endogenous Retroviruses: Role in Negative Selection of T cells in the Thymus and Pathogenesis of Psoriasis” \nOur research elucidates the role of human endogenous retroviruses (HERVs) in biological processes related to T cell immunity\, autoimmunity\, and the pathogenesis of psoriasis. HERVs are ancient viral elements integrated into the human genome. While most of these elements are rendered non-functional due to mutations and epigenetic silencing\, some retain the ability to express themselves. Despite their foreign origin\, the expression of these endogenous retroviruses does not typically trigger autoimmune disease. \nThe study employed single-cell RNA sequencing data from thymic tissues\, revealing that a wide range of HERVs is expressed in thymic cells responsible for presenting autoantigens to T cells and for their subsequent negative selection. This suggests that some HERVs may be perceived by the immune system as autoantigens\, and disruptions in the negative selection process could potentially lead to autoimmune diseases. \nPsoriasis is a T cell-mediated chronic inflammatory skin disease that occurs in predisposed individuals carrying specific HLA-C alleles\, which are crucial for presenting small peptides to T cells that survey for non-self peptides. RNA-seq data from psoriasis-affected tissues highlighted a significant correlation between elevated HERV expression and the development of the disease. These findings emphasize the potential role of HERVs in T cell-mediated conditions and offer new insights into the molecular mechanisms underlying psoriasis.
URL:https://www.biomed.cas.cz/event/seminar-marharyta-klianitskaya-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T223000
DTSTAMP:20260426T160904
CREATED:20240917T085823Z
LAST-MODIFIED:20240917T085823Z
UID:2146-1727460000-1727476200@www.biomed.cas.cz
SUMMARY:Researchers’ Night 2024 at the IEM CAS
DESCRIPTION:The mysterious world of experimental (bio)medicine\nAs night falls\, our laboratories become a dark and magical place where the challenges of biomedicine become a reality. The darkness that surrounds the building creates a unique atmosphere. The light of microscopes shines through the darkness and reveals the secrets of life at the molecular and cellular level. Every click of the pipette\, every flash of fluorescence and every record of information brings our scientists closer to their desired goal of discovering new diagnostic and therapeutic procedures that can change patients‘ lives worldwide. \nCome and experience this feeling in person and visit selected experimental (bio)medicine laboratories. We look forward to welcoming you! \nProgramme\nMore information can be found on the official website (only available in Czech).
URL:https://www.biomed.cas.cz/event/researchers-night-2024-at-the-iem-cas/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240927T180000
DTEND;TZID=Europe/Prague:20240927T220000
DTSTAMP:20260426T160904
CREATED:20240924T130636Z
LAST-MODIFIED:20240924T131704Z
UID:2163-1727460000-1727474400@www.biomed.cas.cz
SUMMARY:Noc vědců
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/noc-vedcu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T130000
DTEND;TZID=Europe/Prague:20240924T140000
DTSTAMP:20260426T160904
CREATED:20240917T082830Z
LAST-MODIFIED:20240917T082922Z
UID:2124-1727182800-1727186400@www.biomed.cas.cz
SUMMARY:IEM CAS μLecture: Two-photon microscopy
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nThe topic of the September seminar will be two-photon microscopy. This technique is especially suitable for the imaging of processes in vivo. We will explain the two-photon microscopy principle\, look at the advantages and disadvantages of this technique and what experiments it can be used for. \nThe seminar will take place on Tuesday 24. 9. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration is not required\, but we will be happy if you can let us know if you plan to come (in person or via email iva.svecova@iem.cas.cz).
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclecture-two-photon-microscopy/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240924T090000
DTEND;TZID=Europe/Prague:20240927T170000
DTSTAMP:20260426T160904
CREATED:20240823T063438Z
LAST-MODIFIED:20240823T063721Z
UID:1222-1727168400-1727456400@www.biomed.cas.cz
SUMMARY:Holotomography Workshop - TOMOCUBE HT-X1
DESCRIPTION:Dear Colleagues\, \nHolotomography is an advanced imaging technique that uses a specialized microscope to capture high-resolution images of biological structures such as bacteria\, cells\, intracellular structures\, or even entire organoids without the need for staining. This method allows for the acquisition of quantitative data\, including dry mass measurements and various other parameters. \nIf you have ever considered exploring quantitative holotomography microscopy techniques or quantitative phase microscopy\, this is an event you should not miss. \nThis workshop is designed for potential users and is fully dedicated to practically introducing holotomography as a quantitative microscopic technique. The method will be demonstrated through hands-on experience with the TOMOCUBE HT-X1 system. \nThe first half-day will take place a series of theoretical lectures\, followed by three days fully dedicated to hands-on sessions. During these sessions\, you will learn how to set up acquisitions\, perform AI-boosted image segmentation\, and analyze quantitative imaging data. \nLed by one of Tomocube’s most advanced application specialists\, Bruno Combettes\, this workshop offers an excellent opportunity to discuss your experimental ideas and design with an expert in the method and system. It is also a unique chance to test your experimental design and ideas on the system\, with expert guidance. \nThis event also provides an opportunity to gain valuable contacts for your future research work… \nFor any questions\, please contact: ivan.novotny@img.cas.cz.  \n 
URL:https://www.biomed.cas.cz/event/holotomography-workshop-tomocube-ht-x1/
LOCATION:IMG
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240923T143000
DTEND;TZID=Europe/Prague:20240923T163000
DTSTAMP:20260426T160904
CREATED:20240913T073932Z
LAST-MODIFIED:20240913T073932Z
UID:1973-1727101800-1727109000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR - PhDr. Pavel Baran\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidátky/kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024.\n \nJedním z kandidátů na předsedu AV ČR je PhDr. Pavel Baran\, CSc.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v pondělí 23. 9. 2024 od 14:30 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-phdr-pavel-baran-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240917
DTEND;VALUE=DATE:20240919
DTSTAMP:20260426T160904
CREATED:20240827T104940Z
LAST-MODIFIED:20240827T104940Z
UID:1225-1726531200-1726703999@www.biomed.cas.cz
SUMMARY:6th CCP Phenogenomics Conference
DESCRIPTION:
URL:https://www.biomed.cas.cz/event/6th-ccp-phenogenomics-conference/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240916T080000
DTEND;TZID=Europe/Prague:20240920T170000
DTSTAMP:20260426T160904
CREATED:20240917T084359Z
LAST-MODIFIED:20240917T084531Z
UID:2142-1726473600-1726851600@www.biomed.cas.cz
SUMMARY:IEM CAS Advanced Course on Preclinical Imaging
DESCRIPTION:Basic information\nThe course aims to teach multimodal preclinical imaging techniques\, including in vivo two-photon microscopy\, in vivo multi-photon-based label-free techniques (SHG\, THG\, CARS)\, and magnetic resonance imaging (MRI) of small rodents. Participants will acquire theoretical knowledge and practical skills in various neuroimaging techniques\, with a focus on intravital multi-photon microscopy and MRI principles. Emphasizing the importance of animal models in physiological research\, the course guides participants through the entire process of conducting preclinical bioimaging experiments. It includes a detailed pipeline for analyzing brain tumour structures and functional parameters\, covering cranial window surgery\, two-photon microscopy usage\, perfusion MRI and subsequent image analysis. Additionally\, the workshop addresses the challenges in using animal models for research and provides access to field experts. \nIntended audience\nThe course is designed for researchers (PhD candidates\, Postdocs\, Principal Investigators\, etc.) with a serious interest in integrating in vivo imaging into their projects. \nMethods\nTwo-photon fluorescent microscopy (functional calcium/voltage imaging\, structural imaging)\, second harmonic generation (SHG)\, third harmonic generation (THG)\, coherent anti-Stokes Raman spectroscopy (CARS)\, high field magnetic resonance perfusion imaging (MRI)\, fluorescence lifetime imaging microscopy (FLIM) \nRegistration and more information can be found on our website.
URL:https://www.biomed.cas.cz/event/iem-cas-advanced-course-on-preclinical-imaging/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240912T140000
DTEND;TZID=Europe/Prague:20240912T150000
DTSTAMP:20260426T160904
CREATED:20240903T124147Z
LAST-MODIFIED:20240903T125118Z
UID:1696-1726149600-1726153200@www.biomed.cas.cz
SUMMARY:IEM CAS Institutional Seminar Series 09/2024
DESCRIPTION:The DNA single-strand break repair capacity of the mammalian oocytes and embryos \nLecturer: Nataliia Dudko\, MSc. / Department of Cell Nucleus Plasticity \nAnnotation: The number of de novo mutations in mammalian oocytes and preimplantation embryos is substantially lower than in somatic cells\, but the reasons for this phenomenon are unknown. In our study we focus on minor DNA lesions repaired via BER\, as they are a common source of de novo mutations. We found that the abundance of BER proteins may not be the most critical factor in granting high genomic stability\, and other factors such as chromatin landscape should be considered. \nThe seminar will take place on 12. 9. 2024 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-institutional-seminar-series-09-2024/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240910T140000
DTEND;TZID=Europe/Prague:20240910T153000
DTSTAMP:20260426T160904
CREATED:20240904T065930Z
LAST-MODIFIED:20240904T065930Z
UID:1701-1725976800-1725982200@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR pro funkční období 2025–2029 - prof. RNDr. David Honys\, Ph.D.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR prof. RNDr. Evě Zažímalové\, CSc. Volba kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024. \nJedním z kandidátů na předsedu AV ČR je prof. RNDr. David Honys\, Ph.D.\, který představí zaměstnancům krčského kampusu svou vizi o řízení AV ČR na jednání v úterý 10. 9. 2024 od 14:00 hod. v sále Milana Haška na ÚMG.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-pro-funkcni-obdobi-2025-2029-prof-rndr-david-honys-ph-d/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240718T150000
DTEND;TZID=Europe/Prague:20240718T163000
DTSTAMP:20260426T160904
CREATED:20240917T083049Z
LAST-MODIFIED:20240917T083057Z
UID:2135-1721314800-1721320200@www.biomed.cas.cz
SUMMARY:IEM CAS Distinguished Guest Seminar Series – Prof. Kai Liu
DESCRIPTION:Lecturer: Prof. Kai Liu / Division of Life Science\, Hong Kong University of Science and Technology \nThe seminar will take place on 18. 07. 2024 from 15:00 in the Turquoise Auditorium of the IEM CAS. \nIntroduction: \nProf. Kai Liu received his Bachelor degree from School of Life Sciences at Peking University in 1998\, and received his Ph.D. from Rutgers University at New Brunswick in 2006. Then he did his postdoc research at Children’s Hospital Boston/Harvard Medical School. He joined Division of Life Science at HKUST as Assistant Professor in 2011\, and is currently Cheng Associate Professor of Science. His research interest focuses on the intrinsic mechanisms regulating axonal regeneration and functional repair after central nervous system injuries.
URL:https://www.biomed.cas.cz/event/iem-cas-distinguished-guest-seminar-series-prof-kai-liu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240718T140000
DTEND;TZID=Europe/Prague:20240718T150000
DTSTAMP:20260426T160904
CREATED:20240917T083319Z
LAST-MODIFIED:20240917T083319Z
UID:2137-1721311200-1721314800@www.biomed.cas.cz
SUMMARY:IEM CAS Distinguished Guest Seminar Series – Cian O'Connor
DESCRIPTION:Lecturer: Cian O’Connor\, PhD. / Tissue engineering research group\, University of Medicine and Health Sciences Dublin \nThe seminar will take place on 18. 07. 2024 from 14:00 in the Turquoise Auditorium of the IEM CAS. \nIntroduction: \nCian O’Connor is a postdoctoral researcher in the Tissue engineering research group led by Prof. Fergal O’Brien\, RCSI & physiology graduate from Trinity College Dublin with an interest in cellular neuroscience and biomaterials. His interest lies in studying glial cells and technological advancements associated with therapeutic treatments particularly via stem cell culture\, development of scaffold implants\, the use of non-viral gene delivery and electroconductive materials. \nWe look forward to your participation.
URL:https://www.biomed.cas.cz/event/iem-cas-distinguished-guest-seminar-series-cian-oconnor/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240626T160000
DTEND;TZID=Europe/Prague:20240626T170000
DTSTAMP:20260426T160904
CREATED:20240612T073038Z
LAST-MODIFIED:20240612T081932Z
UID:932-1719417600-1719421200@www.biomed.cas.cz
SUMMARY:Seminář Prof. Dirk Schübeler
DESCRIPTION:“Finding your place: Transcription factors as sensors and modifiers of chromatin” \nTranscription factors only bind a minority of their motifs in large mammalian genomes. One likely explanation is that many motifs are not accessible for binding due to the action of chromatin and DNA methylation. We are using mammalian stem cell models and their differentiation combined with genomics to understand this important interplay between gene regulation\, chromatin structure and DNA methylation. We study the dynamics of the epigenome and test regulatory models in cellular models by genetic perturbation and genome editing approaches. \nI will discuss our recent efforts in understanding how the sensitivity to DNA methylation and nucleosomes can limit transcription factor binding in the context of the cell and how TFs rely on specific chromatin remodelers for access to their binding sites.
URL:https://www.biomed.cas.cz/event/seminar-prof-dirk-schubeler/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240625T130000
DTEND;TZID=Europe/Prague:20240625T140000
DTSTAMP:20260426T160904
CREATED:20240917T083708Z
LAST-MODIFIED:20240917T083708Z
UID:2140-1719320400-1719324000@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures: Checklists for Publishing Images and Introduction to Image Archives
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers‘ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers‘ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThanks to speedy technological developments\, microscopy images document a significant part of scientific discoveries in this data-intensive era. It is becoming increasingly important to ensure that images are presented in a transparent and reproducible manner. However\, there are only a few guidelines available for publishing terabytes to petabytes of image data\, while research funding agencies require data to be published in open repositories. The objective of this seminar is to provide an overview of the key aspects of data publication\, with a particular focus on image data. In addition\, the seminar will offer a brief introduction to repositories and other relevant resources. \nThe seminar will take place on 25. 6. 2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come.
URL:https://www.biomed.cas.cz/event/iem-cas-%ce%bclectures-checklists-for-publishing-images-and-introduction-to-image-archives/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240620T100000
DTEND;TZID=Europe/Prague:20240620T113000
DTSTAMP:20260426T160904
CREATED:20240605T102859Z
LAST-MODIFIED:20240605T102859Z
UID:927-1718877600-1718883000@www.biomed.cas.cz
SUMMARY:Představení kandidáta na předsedu AV ČR pro funkční období 2025–2029 - Ing. Jiří Plešek\, CSc.
DESCRIPTION:Dne 24. 3. 2025 skončí druhé čtyřleté období ve funkci předsedkyně AV ČR\nprof. RNDr. Evě Zažímalové\, CSc. Volba kandidáta na předsedu AV ČR pro následné funkční období proběhne na zasedání sněmu AV ČR dne 10. 12. 2024. \n\n\n\nJedním z kandidátů na předsedu AV ČR je Ing. Jiří Plešek\, CSc.
URL:https://www.biomed.cas.cz/event/predstaveni-kandidata-na-predsedu-av-cr-pro-funkcni-obdobi-2025-2029-ing-jiri-plesek-csc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240619T150000
DTEND;TZID=Europe/Prague:20240619T160000
DTSTAMP:20260426T160904
CREATED:20240611T060610Z
LAST-MODIFIED:20240611T060610Z
UID:930-1718809200-1718812800@www.biomed.cas.cz
SUMMARY:Seminář Josef Novák\, Ph.D.
DESCRIPTION:“Switch of ADP/ATP translocase isoforms in cellular senescence and malignancy” \nFour isoforms of human ATD/ADP translocators (ANTs) have poorly understood functional differences. Due to their high sequence similarity\, antibody-based detection of these proteins is challenging. We\, therefore\, developed a sensitive proteomic method for detecting ATD/ADP translocator isoforms and their relative ratio. Using this technique\, we observed a switch of ANT isoforms during senescence establishment associated with changes in cellular energy metabolism. The switch of ANT protein isoforms was not correlated with the change of ANT transcripts. Similarly\, we found a non-correlation of ANT transcripts with corresponding proteins in patients‘ glioblastoma and lung cancer samples. We concluded that protein levels of ANT isoforms are regulated on multiple levels and are tightly linked to mitochondria biogenesis.
URL:https://www.biomed.cas.cz/event/seminar-josef-novak-ph-d/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240617T163000
DTEND;TZID=Europe/Prague:20240617T173000
DTSTAMP:20260426T160904
CREATED:20240509T101609Z
LAST-MODIFIED:20240509T101609Z
UID:907-1718641800-1718645400@www.biomed.cas.cz
SUMMARY:Lecture "Obesity cannot be cured\, but increasingly better treated"
DESCRIPTION:Prof. Matthias Blüher\, Director of the Helmholtz Institute for Metabolism\, Obesity and Vasculature research at the Helmholtz Center Munich and the University of Leipzig\, Germany
URL:https://www.biomed.cas.cz/event/lecture-obesity-cannot-be-cured-but-increasingly-better-treated/
LOCATION:Kinosal\, Vídeňská 1083\, Praha
ORGANIZER;CN="FGU":MAILTO:Olga.Zimmermannova@fgu.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T150000
DTEND;TZID=Europe/Prague:20240612T160000
DTSTAMP:20260426T160904
CREATED:20240603T095411Z
LAST-MODIFIED:20240603T095411Z
UID:924-1718204400-1718208000@www.biomed.cas.cz
SUMMARY:Seminář Jiří Březina\, M.Sc.
DESCRIPTION:“How antigens get distributed in the thymus” \nThe presentation of self-antigens in the thymus by medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) is crucial for the establishment of central tolerance. While mTECs produce and present self-antigens in an autonomous manner\, DCs acquire them from mTECs by cooperative antigen transfer (CAT). Although CAT represents a key process of central tolerance\, molecular determinants which define CAT’s effectivity as well as the the capacity of DCs to subsequently present highjacked antigens are largely unknown. To reveal the nature of these determinants\, we compared the transcriptomes of CAT-experienced and inexperienced DCs via scRNAseq. In this seminar\, we will focus on one such a determinant of CAT\, gene product encoding the tight junction protein\, CLAUDIN 1. A series of experiments demonstrated  that CLAUDIN 1 is a regulatory molecule which coordinates CAT and T cell selection processes. The comprehension of these processes will aid in the resolution of the current controversy concerning the role of DCs in central tolerance.
URL:https://www.biomed.cas.cz/event/seminar-jiri-brezina-m-sc/
LOCATION:Posluchárna Milana Haška / Milan Hašek Auditorium
ORGANIZER;CN="%C3%9AMG":MAILTO:leona.krausova@img.cas.cz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Prague:20240612T130000
DTEND;TZID=Europe/Prague:20240612T140000
DTSTAMP:20260426T160904
CREATED:20240523T224952Z
LAST-MODIFIED:20240917T083407Z
UID:919-1718197200-1718200800@www.biomed.cas.cz
SUMMARY:IEM CAS μLectures Seminar Series: Digital Image Basics
DESCRIPTION:μLectures is a monthly seminar series designed to enhance researchers’ understanding of microscopy’s fundamental workings and principles. Each session\, lasting 30 minutes\, focuses on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments\, giving them a better overview of the options available and enabling them to improve their experimental design and more effectively identify and resolve potential issues. \nAnnotation\nThe seminar aims to provide participants with the basic knowledge and skills to work with graphics and digital images. The participants will be introduced to key concepts and techniques. For example\, they will learn how information is stored in a digital image or what bit depth is. Understanding these principles is essential for the proper processing of microscopic data. \nThe seminar will take place on 12.6.2024 from 1 p.m. in the Turquoise Auditorium of the IEM CAS. It will also be possible to join online using this link. \nRegistration\nRegistration is not required\, but we will be happy if you let us know (in person or at iva.svecova@iem.cas.cz) and if we have an idea of how many people are planning to come. \nLecturer\nJan Setnička
URL:https://www.biomed.cas.cz/event/919/
END:VEVENT
END:VCALENDAR