Physiol. Res. 48: 59-63, 1999

The Effect of Branched Chain Amino Acids on Protein Synthesis in Two Skeletal Muscles of Japanese Quail


Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Ivanka pri Dunaji, Slovak Republic

Received June 24, 1998
Accepted October 1, 1998

Two different isolated skeletal muscles of Japanese quail were used. The influence of branched chain amino acids on the fractional rate of protein synthesis (FSR) was evaluated using 14C-tyrosine. The addition of 0.5 mM valine, leucine or isoleucine to the incubation medium significantly decreased (P<0.05) the value of FSR in extensor metacarpalis radialis. In the ambiens muscle only the application of leucine increased the FSR significantly while valine and isoleucine were without any effect.

Key words
Fractional protein synthetic rate - Branched chain amino acids - Japanese quail - Isolated skeletal muscles

© 1999 by the Institute of Physiology, Czech Academy of Sciences