Sex Differences in the Response of Postprandial Lipemia
to a Change from a Low-Fat Low-Cholesterol Diet
to a High-Fat High-Cholesterol Diet
J. Kováø, R. Poledne
Laboratory for Atherosclerosis Research, Institute for Clinical and
Experimental Medicine, Prague, Czech Republic
Received September 3, 1998
Accepted January 11, 1999
Summary
To determine whether a short-term change in dietary habits
affects postprandial lipemia in men and women in the same way, postprandial triglyceridemia was measured in age- and BMI-matched young healthy men and women
after two weeks on the self-selected low-fat low-cholesterol (LF) diet and after
another two weeks on the self-selected high-fat high-cholesterol (HF) diet.
After a standardized challenge meal (1.4 g fat/kg of body weight), men had
higher postprandial triglyceridemia than women on the HF diet but no such
difference was observed on the LF diet. The results of this preliminary study
suggest that there may be important sex differences in the mechanisms regulating
the postprandial lipemia response to different diets, women being able to adapt
better to the HF diet with respect to postprandial lipemia.
Key words
Postprandial lipemia · Plasma triglycerides ·
Gender
Reprint requests
RNDr. J. Kováø,
PhD, Laboratory for Atherosclerosis Research, Institute for Clinical and
Experimental Medicine, Vídeòská 1958/9, 140 21 Prague 4, Czech Republic.
e-mail: jan.kovar@medicon.cz
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