Dorsal Rhizotomy Changes the Spontaneous Neuronal Activity of Nuclei in the
Medial Thalamus
Š. Vaculín, M. Franìk, R. Rokyta
Department of Normal, Pathological and Clinical Physiology, Charles
University, Third Faculty of Medicine, Prague, Czech Republic
Received June 10, 1999
Accepted October 6, 1999
Summary
The aim of this study was to examine the influence of
unilateral dorsal root section at the cervicothoracic level of the spinal cord
on the spontaneous neuronal activity of medial thalamic nuclei in the rat.
Single unit extracellular recordings from thalamic nuclei, nc. parafascicularis
and nc. centralis lateralis, were obtained with glass micropipettes. The
abnormal bursting activity of these nuclei following deafferentation was
registered, although a correlation between the occurrence of this activity and
the degree of autotomy behavior was not found. Such bursts were never observed
in the studied thalamic nuclei of control rats.
Key words
Deafferentation · Medial thalamus ·
Single neuronal unit activity
Reprint requests
Š. Vaculín, Department of Normal, Pathological and Clinical
Physiology, Third Faculty of Medicine, Charles University, Ke Karlovu 4, 120 00
Prague 2, Czech Republic. e-mail: svaculin@lf3.cuni.cz
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