Satellite
Nucleoli in the Megakaryocytic Lineage of Rats
J.
JANOUTOVÁ1, Z. LIKOVSKÝ2,
K. SMETANA3
1Institute
of Histology and Embryology, Third Faculty of
Medicine, Charles University, Prague, Czech
Republic, 2Institute
of Experimental Medicine, Academy of Sciences of
the Czech Republic, Prague, Czech Republic, 3Institute
of Hematology and Blood Transfusion, Prague,
Czech Republic
Received April 14, 2000
Accepted June 28, 2000
Summary
The
present study was undertaken to provide more
information on the incidence of satellite
nucleoli in developmental stages of the
megakaryocytic lineage. Satellite nucleoli
representing solitary silver stained nucleolus
organizer regions (AgNORs) present in nuclei in
addition to other nucleolar types were observed
in all stages of megakaryocytic development.
However, the incidence of satellite nucleoli was
more frequent in mature megakaryocytes than in
less differentiated immature megakaryoblasts and
naked megakaryocytic nuclei representing the
terminal stages of megakaryocytic development
after loss of the cytoplasm transformed to
thrombocytes. There is a possibility that the
increased incidence of satellite nucleoli in
mature megakaryocytes might be due to the loss of
AgNORs from active nucleoli characteristic for
immature cells. The decreased incidence of
satellite nucleoli in naked megakaryocytic nuclei
might reflect their disintegration in the
terminal stages of the megakaryocytic
development.
Key
words
Cell
nucleolus · Megakaryoblast · Megakaryocyte ·
Nucleolus organizer
Reprint
requests
Dr. Z. Likovský, Institute of Experimental
Medicine, Academy of Sciences of the Czech
Republic, Vídeňská 1083, 142 20 Prague 4,
Czech Republic.
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