Activities of
Superoxide Dismutase and Catalase in Erythrocytes
and Plasma Transaminases of Goldfish (Carassius
auratus gibelio Bloch.) Exposed to Cadmium
R.V.
ŽIKIĆ, A. Š. ŠTAJN, S. Z. PAVLOVIĆ1,
B. I. OGNJANOVIĆ, Z. S. SAIĆIĆ1
Faculty
of Sciences, University of Kragujevac,
Kragujevac, Serbia, Yugoslavia, 1Institute
for Biological Research "Siniša
Stanković", Department of Physiology,
Belgrade, Serbia, Yugoslavia
Received November 19, 1999
Accepted March 3, 2000
Summary
Four
groups of goldfish were exposed to cadmium in a
concentration of 20 mg Cd/l water under aquarium
conditions. The duration of exposure was 1, 4, 7
and 15 days. It was shown that the activity of
superoxide dismutase (SOD) in the red blood cells
(RBC) significantly decreased after the first day
of cadmium exposure. However, the SOD activity
increased after 7 and 15 days of cadmium
treatment. Elevated activity of catalase (CAT)
was found in erythrocytes of cadmium-treated
fishes after 15 days, whereas plasma GOT levels
was increased after 7 and 15 days and GPT levels
after 1, 4, 7 and 15 days of cadmium treatment.
This was accompanied by a significant decrease of
blood hemoglobin concentrations (after 15 days)
and hematocrit values (after 7 and 15 days).
However, the concentration of blood glucose
significantly increased after 1, 4, 7 and 15 days
of cadmium exposure. These results indicate that
cadmium causes oxidative stress and tissue damage
in the exposed fishes.
Key
words
Cadmium
· Carassius · Superoxide dismutase · Catalase
· Transaminases
Reprint
requests
Dr. Radoslav V. Žikić, Faculty of Sciences,
University of Kragujevac, Radoja Domanovića 12,
34000 Kragujevac, Serbia, Yugoslavia, e-mail: zikic@uis0.uis.kg.ac.yu
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