Interspike
Background Activity in Extracelullarly Recorded
Purkinje Neurons: Spectral Analysis
J. ŠAPONJIĆ1,
M. ĆULIĆ1, B. JANKOVIĆ2,
A. JOVANOVIĆ3
1Institute
for Biological Research, 2Center
for Multidisciplinary Studies and 3School
of Mathematics, University of Belgrade, Belgrade,
Yugoslavia
Received June 5, 2000
Accepted November 17, 2000
Summary
The
aim of this study was to investigate the spectral
characteristics of Purkinje cell interspike
background activity caused by the occurrence of
particular action potentials or by electrically
induced enhancement of cerebellar inhibitory and
excitatory input drive. Spontaneously active
Purkinje neurons were extracellularly recorded in
anesthetized rats before and after cessation of
stimulation from the inferior olive (IO) or locus
coeruleus (LC). After A/D conversion (30 kHz),
direct spectral analysis of extracted interspike
background activity was done. Our results have
shown that, in contrast to simple spikes, the
occurrence of complex spikes induces changes in
the spectra of interspike background activity.
The different spectral changes of interspike
background activity induced by LC and IO
stimulation also indicated the importance of this
extracellularly recorded phenomenon.
Key
words
Spectral
analysis · Purkinje neurons · Interspike
background activity
Reprint
requests
Jasna
Šaponjić, M.D., Ph.D., Department of
Neurobiology and Immunology, Institute for
Biological Research, 29. novembra 142, 11 000
Belgrade, Yugoslavia. FAX: +381 11 761 , E-mail: jasnasap@ibiss.bg.ac.yu
|
