Volume 51: 199-204, 2002


Visual Event-Related Potentials to Moving Stimuli:
Normative Data


Z. KUBOVÁ, J. KREMLÁČEK1, J. SZANYI1, J. CHLUBNOVÁ1, M. KUBA1

Department of Physiology and
1Department of Pathophysiology, Faculty of Medicine, Charles University, Hradec Králové, Czech Republic


Received February 7, 2001
Accepted June 29, 2001


Summary
Visual cognitive responses (P300) to moving stimuli were tested in 36 subjects with the aim to find the normal range of P300 parameters. Concomitantly, the circadian intra-individual variability of the P300 was studied in a subgroup of 6 subjects. Visual stimuli consisted of either coherent (frequent stimulus) or non-coherent motion (random stimulus). The oddball paradigm was applied for recording cognitive responses. P300 to rare stimuli had an average latency of 447.3±46.6 ms and amplitude of 12.9±6.0 mV. The average reaction time was in the range from 322 to 611 ms and there was no correlation between the reaction time and P300 latency. We did not find any significant circadian changes of the P300 parameters in the 6 subjects tested four times during the same day. Cognitive (event-related) responses (P300) displayed distinctly greater inter-individual variability (S.D. of 50 ms) when compared with pattern-reversal and motion-onset VEPs (S.D. of 6.0 ms and 14 ms, respectively). For this reason, the clinical use of P300 elicited by this kind of visual stimuli seems to be rather restricted and the evaluation of its intra-individual changes is preferable.


Key words
Visual potentials · Evoked potentials · Random stimuli · Coherent stimuli

Reprint requests
Dr. Z. Kubová, Department of Physiology, Faculty of Medicine, Šimkova 870, 500 01 Hradec Králové, Czech Republic. e-mail:
kubova@lfhk.cuni.cz

PHYSIOLOGICAL RESEARCH
© 2002 by the Institute of Physiology, Czech Academy of Sciences

ISSN 0862 - 8408

Issue 2