Visual
Event-Related Potentials to Moving Stimuli:
Normative Data
Z.
KUBOVÁ, J. KREMLÁČEK1, J. SZANYI1,
J. CHLUBNOVÁ1, M. KUBA1
Department of Physiology and 1Department
of Pathophysiology, Faculty of Medicine, Charles
University, Hradec Králové, Czech Republic
Received February 7, 2001
Accepted June 29, 2001
Summary
Visual cognitive responses (P300) to
moving stimuli were tested in 36 subjects with
the aim to find the normal range of P300
parameters. Concomitantly, the circadian
intra-individual variability of the P300 was
studied in a subgroup of 6 subjects. Visual
stimuli consisted of either coherent (frequent
stimulus) or non-coherent motion (random
stimulus). The oddball paradigm was applied for
recording cognitive responses. P300 to rare
stimuli had an average latency of 447.3±46.6 ms
and amplitude of 12.9±6.0 mV. The average
reaction time was in the range from 322 to 611 ms
and there was no correlation between the reaction
time and P300 latency. We did not find any
significant circadian changes of the P300
parameters in the 6 subjects tested four times
during the same day. Cognitive (event-related)
responses (P300) displayed distinctly greater
inter-individual variability (S.D. of 50 ms) when
compared with pattern-reversal and motion-onset
VEPs (S.D. of 6.0 ms and 14 ms, respectively).
For this reason, the clinical use of P300
elicited by this kind of visual stimuli seems to
be rather restricted and the evaluation of its
intra-individual changes is preferable.
Key
words
Visual
potentials · Evoked potentials · Random stimuli
· Coherent stimuli
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Dr. Z. Kubová, Department of Physiology, Faculty
of Medicine, Šimkova 870, 500 01 Hradec
Králové, Czech Republic. e-mail: kubova@lfhk.cuni.cz
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