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REVIEWS
Physiol. Res. 74: 693-710, 2025;
doi:
10.33549/physiolres.935631
Advances in understanding the mechanisms of treatment for gouty arthritis: a comprehensive review.
Sisi Chen, Zeguang Li, Xiaowei Deng, Lijuan Gao
(Dept. Rheumatol., First Affil. Hosp., Heilongjiang Univ. Chinese Med., Harbin, China)
Physiol. Res. 74: 711-727, 2025;
doi:
10.33549/physiolres.935565
The (un-)social brain in isolation.
Allen Fishman, Peleg Grinin, Vladimír Riljak
(Inst. Physiol. First Fac. Med., Charles Univ., Prague, Czech Rep.)
ORIGINAL ARTICLES
Physiol. Res. 74: 729-741, 2025;
doi:
10.33549/physiolres.935650
Effects of isovolumic loading elicited either by 3-branch or by 4-branch spring expander on the degree of cardiac atrophy of the failing heart in rats after heterotopic heart transplantation: no evidence for sex-linked differences.
Luděk Červenka, Iveta Mrázová, Petra Škaroupková, Janusz Sadowski
(Ctr. Exp. Med., Inst. Clin. Exp. Med., Prague, Czech Rep.)
Physiol. Res. 74: 743-753, 2025;
doi:
10.33549/physiolres.935530
Modulatory effect of nimbin on isoproterenol induced mitochondrial and lysosomal enzymes activities and apoptosis signaling in rats.
Yang Wang, Jingli Chen, Haitao Jiang, Xiaoqin Li
(Dept. Cardiovasc. Med., First People’s Hosp. Linping District, Hangzhou Zhejiang, China, Dept. Nephrol., Xiangyang Central Hosp., Affil. Hosp. Hubei Univ. Arts Sci., Xiangfan, Hubei, China)
Physiol. Res. 74: 755-765, 2025;
doi:
10.33549/physiolres.935593
Night-to-day ratio specified by 24-hour blood pressure monitoring, arterial stiffness and cardio-ankle vascular index as predictive factors of cardiovascular risk.
Alena Havelkova, Petr Dvorak, Michal Pohanka,
Petr Dobsak, Jarmila Siegelova, Germaine Cornelissen
(Dept. Sports Med Rehab., St. Anne's Fac. Hosp., Brno,
Czech Rep.)
Physiol. Res. 74: 767-777, 2025;
doi:
10.33549/physiolres.935614
Risk stratification and coronary optical coherence tomography findings in asymptomatic patients with type 1 diabetes mellitus.
Robert Roland, Michal Dubsky, Peter Wohlfahrt, Natalia Marhefkova, Zhi Chen, Milan Sonka, Vladimir Karmazin, Martin Haluzik, Josef Kautzner, Michal Pazdernik
(Dept. Cardiol., Inst. Clin. Exp. Med., Prague, Czech Rep.)
Physiol. Res. 74: 779-795, 2025;
doi:
10.33549/physiolres.935659
Oxidative stress, metabolic impairment and neuroinflammation are associated with target organ damage in SHRSP.
Silvie Hojná, Lucia Mráziková, Anna Shánělová, Helena Pelantová, Augusto Montezano, Rhian M. Touyz, Lenka Maletínská, Jaroslav Kuneš (Inst. Physiol., Czech Acad. Sci., Prague, Czech Rep.)
Physiol. Res. 74: 797-807, 2025;
doi:
10.33549/physiolres.935632
Cinacalcet perturbs membrane permeability of bEND.3 endothelial cells and suppresses cell proliferation.
Yu-Jen Chen, Chen-Hsiu Lin, Cheng-An Wang, Paul Chan, Cing Yu Chen, Yu-Wen Wang, Lian-Ru Shiao, Yuk-Man Leung, Jong-Shiuan Yeh
(Div. Cardiovasc. Med., Dept. Int. Med., Wan Fang Hosp., Taipei Med. Univ., Taipei, Taiwan, Dept. Physiol., China Med. Univ., Taichung, Taiwan)
Physiol. Res. 74: 809-821, 2025;
doi:
10.33549/physiolres.935620
Adipose-derived stem cells pretreated with phototherapy promote HUVECs migration and angiogenesis by mediating EYA1 activation.
Dan Zhang, Yi Zhang, Jia Wen, Biling Wu, Youwen Chen, Yuejiao Song, Chao Liang
(Dept. Anesthesiol., Zhongshan Hosp., Fudan Univ., Xiamen, China)
Physiol. Res. 74: 823-835, 2025;
doi:
10.33549/physiolres.935623
Targeting of miR-93-5p/Mfn2 axis attenuates lung fibrosis in rats with acute respiratory distress syndrome by regulating endoplasmic reticulum stress.
Xiaoxia Zhang, Tao Liu, Zhong Dai, Qin Zhao, Ning An
(Dept. Crit. Care Med., Wuhan Fourth Hosp., Wuhan, Hubei Province, China, Inst. Anesthesiol. Crit. Care, Union Hosp., Tongji Med. Coll., Huazhong Univ. Sci. Technol., Wuhan, China)
Physiol. Res. 74: 837-847, 2025;
doi:
10.33549/physiolres.935586
Serum microRNA-196, -200 and -423 improve diagnostics and differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis.
Pavel Škrha, Aleš Hořínek, Jan Hajer, Jana Potočková, Přemysl Frič, Jan Bureš, Michal Anděl, Jan Škrha
(Sec. Dept. Intern. Med., Third Fac. Med., Charles Univ. Fac. Hosp. Královské Vinohrady, Prague, Czech Rep.)
Physiol. Res. 74: 849-860, 2025;
doi:
10.33549/physiolres.935563
The linkage among gut microbiota, inflammatory cytokines, and immune cell dynamics in osteoporosis: a Mendelian randomization study.
Yuan Guo, Jinghua Du, Hui Chen
(Dept. Med. Lab., Northern Jiangsu People's Hosp. Affil. Yangzhou Univ., Yangzhou City, China, Dept. Sci. Technol., Northern Jiangsu People's Hosp., China)
Physiol. Res. 74: 861-869, 2025;
doi:
10.33549/physiolres.935600
Effect of methylprednisolone on ischemic brain edema after temporary occlusion of the middle cerebral artery in rats.
Petr Kozler, Vít Herynek, Jaroslav Pokorný
(Inst. Physiol., First Fac. Med., Charles Univ., Prague, Czech Rep.)
Physiol. Res. 74: 871-884, 2025;
doi:
10.33549/physiolres.935577
Role of esketamine in attenuating neuroinflammation and improving postoperative cognitive function via autophagy activation through PARP1 targeting.
Chendi Zhao, Jiaxin Liu, Shuang Zhao, Peng Liu, Zhao Li, Yongle Li, Rui Dong, Xiu-Li Wang
(Dept. Anesthesiol., Third Hosp. Hebei Med. Univ., Shijiazhuang, China)
SHORT COMMUNICATION
Physiol. Res. 74: 885-889, 2025;
doi:
10.33549/physiolres.935683
False-positive cardiac troponin elevations in skeletal muscle disease: clinical relevance, mechanisms, and laboratory approaches.
Daniel Rajdl, Marie Šolcová, Jaroslav Racek, David Suchý, Hana Vimmerová, Pavel Broz, Pavel Prokop
(Dept. Clin. Biochem. Hematol., Univ. Hosp. Pilsen Fac. Med. Pilsen, Charles Univ., Pilsen, Czech Rep.)
PROCEEDINGS
Physiol. Res. 74: 1P, 2025
Proceedings of the 26th Conference on Laboratory Animals Science
April 23 – 25, 2025, Tábor, Czech Republic
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