Volume 75, Issue 1, February 2026

 OBITUARY

  • Physiol. Res. 75: 1-2, 2026; doi: 10.33549/physiolres.935808
    Prof. Miloš Langmeier (1951-2025)

    V. Riljak


     REVIEW

  • Physiol. Res. 75: 3-13, 2026; doi: 10.33549/physiolres.935622

    The role of renal Na+/H+ exchange in the regulation of acid-base and sodium homeostasis in premature infants

    Endre Sulyok, Péter Mauchart, Bálint Farkas, Ákos Várnagy, József Bódis
    (Natl. Lab. Human Reprod., Univ. Pécs, Pécs, Hungary)


     ORIGINAL ARTICLES

  • Physiol. Res. 75: 15-27, 2026; doi: 10.33549/physiolres.935673

    Pelargonidin inhibits isoproterenol induced myocardial fibrosis via regulating transforming growth factor-β/Smad2/3 signaling and Th2 cytokines in mice.

    Juanhua Zhao, Linping Dong, Long Yao
    (Seventh Dept. Cardiovasc. Med., Xi'an Internat. Med. Ctr. Hosp., Xi'an, China, Dept. Cardiol., Yan'an People's Hosp., Yan'an, China)

     

  • Physiol. Res. 75: 29-43, 2026; doi: 10.33549/physiolres.935671

    Targeting the toll-like receptor 4 ameliorates heart failure in aged mice by inhibiting the formation of neutrophil extracellular traps

    Huan Liu, Xiangdong Chen, Zhilin Wu
    (Dept. Anesthes., Union Hosp., Tongji Med. Coll., Huazhong Univ. Sci. Technol., Wuhan, China)

     

  • Physiol. Res. 75: 45-53, 2026; doi: 10.33549/physiolres.935691

    Role of PKM2 tetramer in modulating endothelial mitochondrial dysfunction in a rat model of chronic thromboembolic pulmonary hypertension

    Min-Xia Yang, Zhi-Zhu Wu, Da-Wen Wu, Mao-He Chen, Qiu-Xia Wu, Nan Shao, Chao-Sheng Deng
    (Divis. Crit. Care Med., First Affil. Hosp. Fujian Med. Univ., Fuzhou, China)

     

  • Physiol. Res. 75: 55-61, 2026; doi: 10.33549/physiolres.935645

    Platelet count and platelet indices as predictive markers of COVID-19 mortality

    Zuzana Kozelová, Dominika Jarčušková, Ladislav Tomčo, Laura Lacková, Zuzana Kozárová, Marcela Valiková Bavožárová, Lenka Rušinová, Miriam Kozárová
    (Fourth Intern. Dept., Med. Fac. P.J. Safarik Univ., Košice, L. Pasteur Univ. Hosp., Slovak Republic)

     

  • Physiol. Res. 75: 63-77, 2026; doi: 10.33549/physiolres.935642

    RPS3 aggravates sepsis-induced acute kidney injury through activating NF-κB mediated renal inflammatory responses

    Xiaoya Zhang, Qi Ma, Jiangzhong Wang, Zhenqi Zhang, Jun Zhang
    (Dept. Crit. Care Med., Gen. Hosp. of Ningxia Med. Univ., Yinchuan, Ningxia Hui Autonomous Region, China)

     

  • Physiol. Res. 75: 79-87, 2026; doi: 10.33549/physiolres.935639

    Protective effects of opuntiol on lipopolysaccharide-induced acute kidney injury in mice

    Yuan Li, Chunhui Yang, Mengxin Liu, Chunyan Li, Xun Li, Lingqiang Kong
    (Nephrol. Dept., Northwest Univ. First Hosp., Xi'an, China)

     

  • Physiol. Res. 75: 89-98, 2026; doi: 10.33549/physiolres.935612

    TMAO induced kidney aging by activating ZBP1-mediated necroptosis

    Qian Chen, Zhaoxu Qiu, Yaobo Zhao, Lu Bai, Yuhong Chen, Sheng Jin, Fenfen Ma, Jing Dai
    (Dept. Physiol., Hebei Med. Univ., Hebei, China, Dept. Pharm., Shanghai Pudong Hosp., Fudan Univ. Pudong Med. Ctr., Shanghai, China, Dept. Clin. Diagn., Hebei Med. Univ., Hebei, China)

     

  • Physiol. Res. 75: 99, 2026; doi: 10.33549/physiolres.935696

    Bilirubin ameliorates oleic and palmitic acid accumulation in an in vitro model of MASLD

    Kateřina Pospíšilová, Nikola Tulachová, Jakub Onhajzer, Aleš Dvořák, Libor Vítek
    (Inst. Med. Biochem. Labor. Diagn., First Fac. Med., Charles Univ. Gener. Univ. Hosp. Prague, Prague, Czech Republic)

     

  • Physiol. Res. 75: 113-126, 2026; doi: 10.33549/physiolres.935711

    Glucagon-like peptide-2 ameliorates lipid metabolism in metabolic dysfunction‑associated steatotic liver disease through the adiponectin-adiponectin receptor-mediated AMPK/PPARα pathway

    Shu-Juan Zhang, Ke Xu, Feng Zhu, Jun-Guo Chen, Ying Zhang, Yi-Qun Teng, Fang-Fang Shen (Dept. Pediatr., Second Hosp. Jiaxing, Jiaxing Zhejiang, China)

     

  • Physiol. Res. 75: 127-136, 2026; doi: 10.33549/physiolres.935669

    Effects of selected cereal concentrates and a gluten-free diet on ovarian, testicular, and thyroid gland morphology

    Peter Makovický, Michaela Šastná, Lubomír Janda, Petr Jabandžiev, Matěj Hrunka, Edita Jeklová, Adam Norek, Petra Straková, Mária Makovická, Miroslav Chovanec, Klaudia Krážová
    (Dept. Infect. Dis. Prevent. Med., Vet. Res. Inst., Brno, Czech Republic)

     

  • Physiol. Res. 75: 137-148, 2026; doi: 10.33549/physiolres.935675

    Network pharmacological prediction and experimental analyses reveal that naringin alleviates osteoarthritis progression by targeting MMP13

    Min Li, Yunshan Yao, Donglan Huang, Jiao Dai (Dept. Pharm., Chongqing Changshou Women Childen’s Hosp., Chongqing, China, Dept. Breast Thyroid Surg., People’s Hosp. Changshou Chongqing, Chongqing, China, Dept. Pharm., People’s Hosp. Changshou, Chongqing, China)

     

  • Physiol. Res. 75: 149-166, 2026; doi: 10.33549/physiolres.935715

    Task-specific effects of mGlu2/3 receptor agonist LY379268 on MK-801-induced behavioral and neural dysfunctions in rats

    Karolina Hruza, Daniela Cernotova, Kristyna Maleninska, Jan Svoboda, David Levcik, Ales Stuchlik
    (Lab. Neurophysiol. Mem., Inst. Physiol. Czech Acad. Sci., Prague, Czech Republic)

     

  • Physiol. Res. 75: 167-173, 2026; doi: 10.33549/physiolres.935613

    Mirogabalin eliminated pain and reduced inflammation in visceral pain

    Isa Yesilyurt, Soner Bitiktas, Serdar Yigit, Basak Gulakar, Huseyin Fatih Gul
    (Dept. Physiol., Fac. Med., Yalova Univ., Yalova, Republic of Türkiye)

     


    SHORT ARTICLES

  • Physiol. Res. 75: 175-181, 2026; doi: 10.33549/physiolres.935636

    Alteration of mitochondrial Ca2+ fluxes by kaempferol and CGP-37157 regulates Ca2+ oscillations in human alveolar type 2 A549 cells

    King-Chuen Wu, Cing-Yu Chen, Lian-Ru Shiao, Zih-He Yang, Chin-Min Chuang, Yuk-Man Leung
    (Dept. Anesthesiol., Chang Gung Memorial Hosp., Chiayi, Taiwan, Dept. Physiol., China Med. Univ., Taichung, Taiwan, Dept. Emerg. Med., China Med. Univ. Hosp., Taichung, Taiwan)

     

  • Physiol. Res. 75: 183-185, 2026; doi: 10.33549/physiolres.935721

    Mechanical analysis of needles used in ultrasound-guided musculoskeletal interventions

    Tomas Novotny, Daniel Hadraba, Kamal Mezian, Levent Özçakar
    (Dept. Orthop., Fac. Health Studies, Jan Evangelista Purkyne Univ. Usti nad Labem Masaryk Hosp., Usti nad Labem, Czech Republic

     

  • Physiol. Res. 75: 187-192, 2026; doi: 10.33549/physiolres.935714

    Dose-dependent impact of metformin on osteoblast-specific biomarkers in cultured rat primary osteoblasts

    Monika Martiniakova, Anna Sarocka, Vladimira Mondockova, Noemi Penzes, Veronika Kovacova, Roman Biro, Radoslav Omelka
    (Dept. Zool. Anthropol., Dept. Botany Genet., Fac. Natur. Sci. Inform., Constantine the Philosopher Univ. Nitra, Nitra, Slovak Republic)

     

     

  • Š 2026 by the Institute of Physiology, Czech Academy of Sciences