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Welcome to the homepage of the Laboratory of Regulation of Gene Expression.
Our laboratory, established in June 2006, investigates a basic concept of translation and various aspects of its regulation. The studies combine the use of budding yeast Saccharomyces cerevisiae and mammalian cells lines and employ tools of molecular and structural biology, biochemistry and genetics.
Our laboratory is supported by the world-renowned funding bodies such as the Wellcome Trust and Howard Hughes Medical Institute, together with the Czech Grant Agency.
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Open positions
There are currently no open positions in our laboratory, but we may open some in mid-2012 depending on the lab space that we have been promissed to be given with.
News as of Sept 23, 2011
Vanda's PLoS Genetics and Anicka's NAR papers are out, Tomas's NAR manuscript is waiting for its last "push" to be completed soon. Overall this year is a pretty good year for LRGE! Anicka and Vanda are getting ready for their state exams, the first step towards their doctoral degrees - fingers crossed! Petra spent two summer months in Jon Lorsch's lab and thus started our new collaboration with Jon's and Alan Hinnebusch's labs. Vladka received her bachelor's degree in June 2011. Lucie Peclinovska joined us as a bachelor student in Sept 2011.
We are still mostly living off the great Wellcome Trust support, in addition to the running out HHMI grant and two mid-term GACR grants - cannot complain! Martina's manuscript is nearly finished awaiting for its first (and hopefully the last!) submission ;) One more study, originally initiated by Pista, is also nearly ready to be marketed. Lucka's and Petra's termination&recycling story, featuring eIF3 as the main character, is under a decisive way with a huge promise for the great paper! Hope it reaches its Hollywood-ending ;)
Summer time, rich in rainy days, has passed by with a speed of light, it feels very pleasant out there these days - don't get me sentimental here ;)
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