“Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough”

Imagine a gene is a sentence starting with a capital letter and ending with a period, and a genome as a book telling an entire story. In some protozoans, extra periods infiltrated their sentences, replacing specific letters of arbitrary words (namely E and W). As a r.sult, r.aders (ribosom.s) are confus.d about .here these sentenc.s really .nd, and the story b.comes disjoint.d. We described how these protozoans handled this mystery, shedding a new light on (non)universality of the genetic code.