Akce

“Probing the functional heterogeneity and hierarchy in mammary gland fibroblasts” In this talk, I will focus on the heterogeneity and hierarchy of mouse mammary fibroblasts - the predominant cell type of mammary stroma. By single cell RNA sequencing, genetic lineage tracing and microscopy we show that fibroblast transcriptomic clusters represent spatially differentiated populations with specific…
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Poučení z covidové epidemie – co dělat příště jinak Covidová krize v letech 2020-2022 výrazně zasáhla do životů nás všech. Co se udělalo dobře a co naopak špatně? Jak obstáli občané, politici, vědci a zdravotníci? Jak je možné, že se americkým ministrem zdravotnictví stává výrazný antivaxer a šiřitel „fejků“? Pochází covidový virus z přírody nebo z laboratoře? Pomohou nám…
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Silvie Hojná: Anorexigenic neuropeptides in the treatment of obesity Obesity and its complications have reached epidemic proportions. Therefore, finding new, more effective drugs for the treatment of obesity without side effects is a major challenge. Natural anorexigenic neuropeptides have this potential, but their major disadvantage is their low stability in plasma and inability to cross…
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“Live-cell magnetic micromanipulation of recycling endosomes reveals their direct effect on actin-based protrusions to promote invasive migration” Endocytic recycling pathways play key roles in the re-routing of cargoes through the cell to control a broad range of cellular processes, and many vesicle trafficking regulators are implicated in progression of disease such as cancer. The Rab11…
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Dear Colleagues, the Institute of Molecular Genetics of the Czech Academy of Sciences would like to invite you to the 5-day course "Processing and analysis of microscopic images in biomedicine (PAMIB25)" intended for PhD students and junior researchers. The course will address fundamental aspects of image data acquisition, processing, and analysis, encompassing techniques in stereology.…
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„Etika a integrita vědeckého výzkumu a právní otázky“ Seminář se zaměří na témata: testy vědecké integrity; kdy zapojovat etické komise při řešení deliktů na pracovišti; význam závěrů etických komisí v právních přístupech; autorský zákon v praxi a z hlediska práva. JUDr. Ján Matejka, Ph.D. ředitel Ústavu státu a práva AV ČR, v. v. i.

“Life Through Colors: Single-cell fluorescence-based reporter system for monitoring gene expression” The presentation will depict a long journey from decision to actual making a novel reporter system for RNA silencing, which could also be adopted for studying other mechanisms manipulating gene expression. This development lead to production of two types of triple-color reporter HeLa lines…
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Dear imaging users, we would  like to inform you about the Image Data Community Days that will be happening from 7-11. April this year. This free week-long online event will bring together Euro-BioImaging Node staff, researchers and other experts from around the world to explore and exchange on the latest advances in image data through…
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“Analysis of a novel chicken Pax6 mutant”  Pax6 is known as the "master control gene" for eye formation, playing a crucial role in the development of the lens, retina, and other ocular structures. It drives the formation of the eye field, initiates lens differentiation, and helps establish the retina—all vital for vision. While the role of Pax6 in…
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“Deciphering PNKP Functions in Neurological Disorders” Hereditary mutations in polynucleotide kinase-phosphatase (PNKP), a key enzyme in DNA strand break repair, result in a broad spectrum of neurological disorders, ranging from mild neurodegeneration to severe neurodevelopmental defects. PNKP has dual phosphatase and kinase activities essential for DNA break repair, but their specific contributions to preventing neuropathology…
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“Preclinical development of IL-15-based immunocytokine SOT201 and antibody-drug conjugate SOT106 for treatment of solid tumors” SOT201 is a novel cis-acting immunocytokine consisting of an antibody against PD-1 genetically fused to a sushi+ domain of IL-15Ra and IL-15 mutein. SOT201 targets PD-1+ TILs with a balanced cytokine potency to revive exhausted T cells in tumor microenvironment.…
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Dear friends and colleagues, it is my pleasure to invite you to a special seminar given by                       Prof. Sophie Janssens, PhD. VIB-UGent Center for Inflammation Research, Belgium Title: The unfolded protein sensor IRE1 as a regulator of homeostatic dendritic cell maturation   Monday, April 28, 2025 at 10 am, in Hasek's lecture hall, Institute…
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