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Lecture „The role of ryanodine receptors in muscle function“ Ryanodine receptors (RyR) are the Ca2+ release channel of skeletal muscle, which are responsible for rapidly releasing a large amount of Ca2+ upon electrical stimulation to evoke contraction. In the resting muscle, RyR leak Ca2+ and require the expenditure of energy to maintain steady state Ca2+…
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Prof. Bradley Launikonis, The University of Queensland, Brisbane, Australia

“Ontogeny of zebrafish erythropoietic waves” Hematopoiesis is the process of blood formation, which occurs in multiple waves during vertebrate development. In zebrafish, the first wave initiates before 24 hours post-fertilization with the generation of primitive myeloid cells from cephalic mesoderm and primitive erythrocytes in the intermediate cell mass. The first definitive wave is transient, and…
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We would like to invite you to the seminar ********************************** Dr. Marjorie Pion "Adoptive cell therapy with Treg cells obtained from thymic tissue (thyTreg): from a clinical trial using autologous cells to preclinical research exploring allogeneic applications" The seminar will be held on 3rd July 2025 at 15:00 in the Lecture room (0.195) at IMG.…
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Dear colleagues and members of the research community, It is my great pleasure to invite you to the 7th Annual CCP Phenogenomics Conference, taking place on September 11–12, 2025 at the Institute of Molecular Genetics in Prague. Continuing a tradition of scientific excellence, this hybrid conference offers a unique forum to exchange knowledge and advance…
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“Regulation of microtubule organization in glioblastoma cells by GIT2 phosphorylation” Glioblastoma, the most aggressive common type of brain cancer in humans, carries a very poor prognosis for patient survival. Microtubules are critical for cell division and mesenchymal migration, processes that strongly influence tumor viability and invasiveness. While the reorganization of highly dynamic microtubules is central…
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“How Cells Keep DNA Replication in Check” Accurate DNA replication is the foundation of genome stability and cell survival. Our study uncovers a key “gatekeeper” complex that ensures the molecular machinery starting DNA replication is properly assembled and regulated. When this control breaks down, replication becomes uncoordinated, leading to stress, genetic instability, and changes often…
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Department of Microbiology, College of Medicine, Yonsei University, Seoul, South Korea “Intrinsic mechanisms governing B cell discrimination between self and non-self antigens”

Dear colleagues and friends, This year marks the 100th anniversary of the birth of Prof. Milan Hašek (October 4, 1925), a giant of Czech immunology. He was not only an outstanding scientist, immunologist, biologist, and physician, but also an inspiring mentor to an entire generation of researchers, many of whom emigrated after 1968 and became…
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“Ontogeny of zebrafish erythropoietic waves” Hematopoiesis is the process of blood formation, which occurs in multiple waves during vertebrate development. In zebrafish, the first wave initiates before 24 hours post-fertilization with the generation of primitive myeloid cells from cephalic mesoderm and primitive erythrocytes in the intermediate cell mass. The first definitive wave is transient, and…
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“Role of B cells in central T cell tolerance” Tolerance to self-antigens is a fundamental property of the immune system. During central tolerance induction in the thymus, autoreactive T cells are either eliminated or diverted into the regulatory T cell lineage. Both processes are dependent on the presentation of self-antigens by thymic antigen presenting cells…
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