Akce

“Role of B cells in central T cell tolerance” Tolerance to self-antigens is a fundamental property of the immune system. During central tolerance induction in the thymus, autoreactive T cells are either eliminated or diverted into the regulatory T cell lineage. Both processes are dependent on the presentation of self-antigens by thymic antigen presenting cells…
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“The atlas of placodal development helps to decipher their evolutionary origin” In this talk I will present our single cell and spatial transcriptomics data, which I will place into the light of the current ideas about the placodal evolution. Neurogenic placodes are specialized embryonic ectodermal thickenings in the head that give rise to sensory neurons,…
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Dear colleagues, on November 18th 2025 we will organize FlowJo™ 11 training with Ioannis Panetas, Ph.D.- application specialist from BD. FlowJo is a powerful cytometry data analysis software available to users of our Flow Cytometry Core Facility. More information about FlowJo: https://www.flowjo.com/solutions/flowjo This year, the training will focus on the new version 11, which, in…
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“Understanding the enteric nervous system development through the avian embryo model: implications for regenerative biology” In this presentation, I will provide an overview of enteric nervous system (ENS) development from the perspective of the avian embryo. The ENS, often referred to as the “second brain,” originates from vagal neural crest cells that migrate into the…
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“The immunoregulatory properties of the metabolite itaconate” In this talk I will present my latest findings of the function of immunoregulatory metabolite itaconate. Itaconate accumulates in innate immune cells upon Toll-like receptor stimulation. In response to macrophage activation by lipopolysaccharide, itaconate inhibits inflammasome activation and boosts type I interferon signalling; however, the molecular mechanism of…
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