Akce

“HSCs in inflammation: go extramedullary or go home” Hematopoietic stem cells (HSCs) are a rare cell type residing in the bone marrow and giving rise to all hematopoietic cells. Despite their quiescence, HSCs respond to extracellular signals which regulate their fate. In this presentation, we will determine how of chronic inflammation affects HSC location and…
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The role of miR-20a in the injured CNS Lecturer: Mgr. Ivan Arzhanov / Department of Neuroregeneration Annotation: Spinal cord injury (SCI) involves damage to any part of the spinal cord, leading to nervous cell death and disruption of conduction pathways. This damage results in the loss of motor and sensory function below the injury site, potentially causing paralysis and,…
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“Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough” Imagine a gene is a sentence starting with a capital letter and ending with a period, and a genome as a book telling an entire story. In some protozoans, extra periods infiltrated their sentences, replacing specific letters of arbitrary words (namely E and W). As…
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“PPM1D activity promotes genome instability and cellular transformation” Protein phosphatase magnesium dependent 1 (PPM1D) is a negative regulator of the tumour suppressor p53 and is implicated in termination of DNA damage response. Increased PPM1D activity allows proliferation in the presence of DNA breaks caused by ionizing radiation or replication stress induced by expression of active…
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Martin Balaštík, Ph.D., Laboratory of Molecular Neurobiology, IPHYS

Přednášející:  prof. Ing. Jiří Homola, CSc., DSc. Organizace přednášky byla projednána a schválena na schůzi Rady areálu dne 15.1.2024. Vzhledem k projednávanému tématu a v návaznosti na administraci procesu hodnocení, se přednáška bude konat pouze v českém jazyce.

“Knocking out spo11 in chicken arrests meiosis but does not prevent further development of germ cells” Knockout of the mouse spo11 prevents double-strand breaks and formation of synaptonemal complex during meiosis. As a result, the development of spermatocytes is arrested at zygotene and the arrested cells undergo apoptosis. Not so in the chicken. Here, although…
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Studujete vysokou školu přírodovědeckého nebo medicínského zaměření? Připravili jsme pro vás speciální den otevřených dveří s nabídkou zajímavých témat pro vaši bakalářskou či magisterskou práci i témata pro studium PhD. Vědci z FGÚ vás s nimi seznámí v dopoledním bloku (prezenční i online formou) a odpoledne budete mít možnost nahlédnout přímo do jejich laboratoří. Celý program je v…
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μLectures is a new, monthly seminar series designed to enhance researchers’ understanding of the fundamental workings and principles of microscopy. Each session, lasting 30 minutes, will focus on a specific concept or topic within microscopy. The practical information presented aims to deepen researchers’ comprehension of their microscopy experiments, giving them better overview of the options available…
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“Splicing in the world of marine diplonemids” Recent surveys of marine biodiversity have revealed the abundance and diversity of planktonic diplonemids. By sequencing the genomes and transcriptomes of six marine diplonemids and performing comprehensive splice site analyses, we identified numerous non-canonical introns and mapped their common features, shedding light on the evolution of RNA splicing…
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Dr. Ingo Greger, Neurobiology Division MRC Laboratory of Molecular Biology, Cambridge, UK

“Role of pax6 genes in the eye during embryonal development of medaka” Pax6 is remarkably conserved across a wide range of species, from flies to humans, signifying its fundamental role in the regulatory network governing eye formation. In this presentation, we will delve into the functions of three pax6 genes – Pax6.1, Pax6.2, and Pax6.3…
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