Akce

Prohlídka laboratoří, ukázky experimentů v oblasti molekulární genetiky, imunologie, buněčné biologie, virologie, prohlídka posterů a diskuse k vybraným tématům.

“Homologous Recombination - From Repair of DSBs to Processing Stalled Replication Forks and Human Diseases” Our lab focuses on the mechanisms ensuring accurate DNA replication and the role of homologous recombination (HR) in preventing genome instability. We investigate how endogenous hard-to-replicate regions, G-quadruplexes (G4) and R-loops, impact replication and contribute to disease development. A key…
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Max Planck Institute for Medical Research, Heidelberg “Viruses of unicellular eukaryotes: A tale of giants and hyperparasites” Viruses of protists play important roles in ecology and evolution by influencing microbial population dynamics and shaping eukaryotic genomes by endogenization. Of particular interest are complex DNA viruses whose particle and genome sizes overlap with those of bacteria.…
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BBMRI.cz - The Network of Czech Biobanks: Access to human samples

We are pleased to announce the annual mini-symposium BIOCEV Regeneration IV, which will be held on November 26th, 2024, in BIOCEV Centre, Vestec. BIOCEV Regeneration is an annual open one-day mini-symposium that brings together researchers from different fields of biomedicine, from regenerative medicine and tissue engineering to cancer research, drug discovery, and cryobiology. This year,…
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Due to reaching capacity for in-person participation, registration is now only available for online attendance. Thank you for your understanding.  Basic information The course is tailored to users already familiar with the basics of image processing. It will be focused on automatization, high throughput and basic scripting. Course participants will learn how to create and…
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“CRL4COP1 ubiquitination complex as a balancer of early odontogenesis” Cullin-RING ubiquitin ligase (CRL) complexes have been heavily studied in connection to cancer progression but there is limited evidence about their physiological roles. One of the exceptions is disruption of limb development by thalidomide induced by inhibition of CRL4 complex via regulation of Fgf8 (Ito et…
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The course is very practically-oriented, theoretical lectures are followed by 6 hours of hands-on session every day in small groups. You will learn widefield, confocal, and advanced methods including super-resolution, photomanipulation, and FLIM. You will have a chance to work on high-end microscopes and compare wide variety of approaches and instrumentation. For detailed program and…
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“Every stick has two ends – Using high resolution imaging to characterize both ends of the eukaryotic flagellum” The eukaryotic flagellum is important for cell motility. The microtubule-based axoneme generating the flagellar beating has been extensively studied. However, additional structures are associated with the proximal and distal end of the flagellum, with their composition and…
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Trace Element and Speciation Analysis in Biological and Environmental Samples

The human eye is our primary tool for interpreting images, so scientific images should be adjusted with this perception in mind. However, display and print transfer characteristics often degrade images, making them differ from reality. This course offers a unique approach, focusing on preparing image data for presentation. We’ll cover essential topics like gamma correction…
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“Quality control in snRNP biogenesis” Before being assembled into spliceosomes, small nuclear ribonucleoprotein particles (snRNPs) undergo a complex and regulated maturation pathway. Cajal bodies (CBs) have been shown to monitor the final stage of this process by sequestering immature or misassembled particles through a yet unknown quality control mechanism. Here, we have identified coilin, a…
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