Single-cell gene expression analysis of developing craniofacial region Lecturer: Erika Hudáčová, M.Sc. / Department of Developmental Biology The seminar will take place on 2. 11. 2023 from 2 p.m. in the Turquoise Auditorium of the IEM CAS. Annotation: In vertebrates, the skull is composed of various skeletal elements originating from cranial neural crest cells (CNCCs). CNCCs are responsible for the formation of the cranium vault,… Více
Week of the Czech Academy of Sciences is a science festival that follows the previous Week of Science and Technology of the CAS. The festival offers scientific lectures, exhibitions, events at institutes, documentary films, workshops and many other activities across the Czech Republic and all scientific disciplines. As part of the festival, the IEM CAS… Více
“Genetic architecture of Prdm9-driven reproductive isolation between mouse subspecies” Hybrid incompatibility, the inviability or infertility of species hybrids, has played a central role in speciation research since Darwin's Origin of Species. However, the search for genes controlling hybrid sterility, mainly using Drosophila species hybrids, has been largely unsuccessful, revealing a polygenic control with complex epistatic… Více
ABC transporter blood-brain barrier function in neurodegenerative and neuroinflammatory diseases – from basic research to treatment Lecturer: Prof. Jens Pahnke, M.D., Ph.D., E.F.N./ University of Oslo, Faculty of Medicine / Oslo University Hospital, Department of Pathology, Norway The seminar will take place on 20. 11. 2023 from 2:30 p.m. in the Turquoise Auditorium of the IEM CAS. Annotation: The current understanding of… Více
“A chance for fertility despite bad DNA breaks (AKA The effect of crossing-over rate on fertility)” Programmed meiotic DNA breaks are essential for mammalian fertility but dangerous for genome integrity. DNA-binding H3-lysine-trimethyltransferase PRDM9 determines the positions of the meiotic DNA breaks, which can be repaired as crossovers or noncrossovers. The crossover/noncrossover decision is regulated by many… Více
Dear Colleagues, We are pleased to announce the annual Mini-Symposium BIOCEV Regeneration III, which will be held on 23-24th November 2023 in BIOCEV, Vestec. Our symposium aims to exchange knowledge in regenerative medicine, tissue engineering, 3D in vitro modelling, organoid research, new tools and technologies in cell culture, and many more. Along with several lectures given by… Více