Akce

“Multiple Layers of Control in Early Sphingolipid Biosynthesis” Sphingolipids are fundamental components of cellular membranes and key mediators of intracellular signaling. Their de novo synthesis is initiated in the endoplasmic…
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“Integration and reactivation of endogenous DNA viruses in unicellular eukaryotes” Viruses infecting protists play important ecological and evolutionary roles by modulating microbial population dynamics and contributing to genome evolution through…
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“From virus-host interactions to a novel protein delivery tool” The VIIRAL lab has advanced the understanding of species-specific virus-host interactions against retroviruses. This advancement facilitates now the development of a…
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“Therapeutic targeting of stem cells and their niches in myeloid malignancies” Our research group “Stem Cells, Ageing and Cancer” aims at providing insights into mechanisms of hematopoietic stem cell malignant transformation,…
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“Harnessing TCR Discoveries for the Next Generation of Immunotherapies” Recent advances in synthetic immunology and CAR T cell engineering have highlighted the critical importance of signaling diversity for optimizing anti-tumor…
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“NG2-lineage cell plasticity in ischemic brain repair: Roles of Wnt signaling” Focal cerebral ischemia (FCI) leads to neuronal loss followed by extensive tissue remodeling, in which glial and vascular cell populations…
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“Initiating Mechanisms of Autoinflammatory Osteomyelitis: dysregulated neutrophil recruitment and tyrosine kinase signaling” Autoinflammatory diseases result from inappropriate activation of the innate immune system in the absence of infection. Loss of…
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