svoboda@iach.cz

(+420) 296 442 487
(+420) 296 442 499
(+420) 296 442 482

Research ID: AAI-2096-2020

research interest:

generation of volatile compounds, dielectric barrier plasma atomizers, glow discharges, speciation analysis, cryogenic trapping and in-atomizer trapping, gas chromatography, application of radioactive indicators, trace element analysis of industrial, environmental and biological samples;

EDUCATION

• 2012 Ph.D., 2013 RNDr.: Analytical Chemistry, Faculty of Science, Department of Analytical Chemistry, Charles University in Prague and Institute of Analytical Chemistry of the AS CR, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague (supervisor: doc. Jiří Dědina, DSc.). Ph.D. Thesis: Hydride generation study for arsenic speciation analysis with AAS and AFS detection.


• 2006 Mgr. (MSc.): Analytical Chemistry, Faculty of Science, Charles University in Prague and Institute of Analytical Chemistry of the AS CR, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague. Master thesis: Hydride generation for arsenic speciation analysis by atomic absorption spectrometry.


• 1997-2001: Střední průmyslová škola chemická (High School) (Analytical Chemistry of Environment), Pardubice.

POSITIONS AND EMPLOYMENT

• since 2023: Researcher, Institute of Analytical Chemistry of the CAS, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague.


• since 2023: Locomotive engineer, České Dráhy a.s. (Czech Railways)


• 2019-2022: Research assistant, Institute of Analytical Chemistry of the CAS, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague.


• 2018-2019: Locomotive engineer, České Dráhy a.s. (Czech Railways)


• 2013-2018: Postdoc, Institute of Analytical Chemistry of the CAS, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague.


• 2011-2013: Sales representative, Hach-Lange s.r.o., Czech Republic.


• 2004-2010: Institute of Analytical Chemistry of the AS CR, v.v.i., Detached workplace - Department of Trace Element Analysis, Prague (supervisor: doc. Jiří Dědina, DSc.)

PARTICIPATION IN CURRENT GRANT PROJECTS

• Versatile plasma sources and advanced approaches to signal evaluation as novel concepts in ultratrace element analysis by atomic spectrometry. Czech Science Foundation, project no. 23-05974K, 2023-2025.
• Next generation of dielectric barrier plasma discharges as atomizers for ultratrace element and speciation analysis" Czech Science Foundation, project no. 21-05285S , 2021-2023.

PROFESSIONAL INTEREST

• member of the Czech chemical society


• member of the Ioannes Marcus Marci Spectroscopic Society

AWARDS AND SCHOLARSHIPS

• 2016 The best poster presentation at XXI Slovak-Czech Spectroscopic Conference, Liptovský Ján, Slovakia, October 16-20, 2016.


• 2014 Elsevier´s Spectrochimica Acta Part B: Atomic Spectroscopy Poster Award, 13th Rio Symposium on Atomic Spectrometry, Merida, Yucatan - Mexico, 19.-24.10.2014.


• 2010 2.-3. Poster Prize at the XIV. Czech-Slovak spectroscopic conference sponsored by Thermo Fisher Scientific, Litomyšl, 31.5.-3.6.2010.


• 2007 Poster Prize at the XIII. Czech spectroscopic conference. 18.-21. June 2007, Lednice.

LIST OF PATENTS

• SVOBODA M., KRATZER J., DĚDINA J.: Atomizer of volatile compounds based on a dielectric barrier discharge with capillary-shaped electrodes. Czech patent no. 306804, issued by Industrial Property Office of the Czech Republic (12.7. 2017).

LIST OF PUBLICATIONS

• POURALI P., NEUHÖFEROVÁ E., DZMITRUK V., SVOBODA M., STODULKOVÁ E., FLEGER M., BEHROOZ Y., BENSON V.: Bioproduced Nanoparticles Deliver Multiple Cargoes via Targeted Tumor Therapy In Vivo. ACS Omega 9, 31, (2024) 33789–33804.
• POURALI P., SVOBODA M., NEUHÖFEROVÁ E., DZMITRUK V., BENSON V.: Accumulation and toxicity of biologically produced gold nanoparticles in different types of specialized mammalian cells. Biotechnology and Applied Biochemistry (2024) 1–13.
• VLČKOVÁ N., BARANOVÁ B., SVOBODA M., KRATZER J.: Diffusion flame, heated quartz tube or dielectric barrier discharge? Comparing the resistance of hydride atomizers towards interferences with detection by atomic absorption spectrometry. Spectrochimica Acta Part B 212 (2024) 106853.
• SLOTA A., SVOBODA M., SUCHOPÁR V., KRATZER J.: Determination of Germanium Species by Hydride Generation Atomic Absorption Spectrometry: Comparison of Atomizers Based on Diffusion Flame, Heated Quartz Tube, and Dielectric Barrier Discharge Plasma. Atomic Spectroscopy 44 (2023) 207-218.
• POURALI P., DZMITRUK V., BENADA O., SVOBODA M., BENSON V.: Conjugation of microbial-derived gold nanoparticles to different types of nucleic acids: evaluation of transfection efficiency. Scientific Reports 13 (2023) 14669 .
• POURALI P., SVOBODA M., BENADA O., DZMITRUK V., BENSON V.: Biological Production of Gold Nanoparticles at DifferentTemperatures: Efficiency Assessment. Particle & Particle Systems Characterization (2023) 2200182.
• POURALI P., DZMITRUK V., PÁTEK M., NEUHÖFEROVÁ E., SVOBODA M., BENSON V.: Fate of the capping agent of biologically produced gold nanoparticles and adsorption of enzymes onto their surface. Scientific Reports 13 (2023) 4916.
• COELHO JUNIOR da S. G., BORGES D., SVOBODA M., DĚDINA J., KRATZER J.: Plasma-mediated vapor generation of mercury species in a dielectric barrier discharge: Direct analysis in a single drop by atomic absorption spectrometry, Spectrochimica Acta Part B 200 (2023) 106596.
• BARANOVÁ B., KRÁĹOVÁ Z., SVOBODA M., SUCHOPÁR V., BURHENN S., BRANDT S., FRANZKE J. KRATZER J.: Next generation of dielectric barrier discharge hydride atomizers for atomic absorption spectrometry: a case study on Pb, Bi, Se and Te. Spectrochimica Acta Part B 199 (2023) 106577.
• OLIVEIRA A. F., SVOBODA M., BENADA O., KRATZER J.: Ultratrace determination of arsenic by hydride generation atomic absorption spectrometry with preconcentration on gold nanoparticles. Journal of Analytical Atomic Spectrometry 37 (2022), 620-631.
• MRKVIČKOVÁ M., DVOŘÁK P., SVOBODA M., KRATZER J., VORÁČ J., DĚDINA J.: Dealing with saturation of the laser-induced fluorescence signal – An application to lead atoms. Combustion and Flame 241 (2022) 112100.
• SAGAPOVA L., MUSIL S., KODRIKOVÁ B., SVOBODA M., KRATZER J.: Effect of additives on cadmium chemical vapor generation and reliable quantification of generation efficiency. Analytica Chimica Acta 1168 (2021) 338601.
• OLIVEIRA A. F., SVOBODA M., MUSIL S., MACHADO I., VANĚK D., MATOUŠEK T., DĚDINA J., KRATZER J.: Selenium preconcentration in a gold “amalgamator” after hydride generation for atomic spectrometry. Journal of Analytical Atomic Spectrometry 35 (2020), 2132–2141.
• ALBRECHT M., MRKVIČKOVÁ M., SVOBODA M., HRANÍČEK J., VORÁČ J., DVOŘÁK P., DĚDINA J., KRATZER J.: Atomization of lead hydride in a dielectric barrier discharge atomizer: Optimized for atomic absorption spectrometry and studied by laser induced fluorescence. Spectrochimica Acta Part B, 166 (2020), 105819.
• KRATZER J., MUSIL S., MARSCHNER, K., SVOBODA M., STURGEON R., MESTER Z., DĚDINA J.: Behavior of selenium hydride in heated quartz tube and dielectric barrier discharge atomizers. Analytica Chimica Acta 1028 (2018), 11-21.
• BURHENN S., KRATZER J., SVOBODA M., KLUTE F. D., MICHELS A., VEŽA D., FRANZKE J.: Spatially and Temporally Resolved Detection of Arsenic in a Capillary Dielectric Barrier Discharge by Hydride Generation High-Resolved Optical Emission Spectrometry. Analytical Chemistry, 90 (2018), 3424-3429.
• HUBER C. S., VALE M. G. R., DESSUY M. B., SVOBODA M., MUSIL S., DĚDINA J.: Sample preparation for arsenic speciation analysis in baby food by generation of substituted arsines with atomic absorption spectrometry detection. Talanta, 175 (2017), 406–412.
• KRATZER J., ZELINA O., SVOBODA M., STURGEON R., MESTER Z., DĚDINA J.: Atomization of Bismuthane in a Novel Dielectric Barrier Discharge – A Mechanistic Study. Analytical Chemistry 88 (2016), 1804−1811.
• SVOBODA M., KRATZER J., VOBECKÝ M., DĚDINA J.: A miniaturized cryogenic trap design for collection of arsanes. Spectrochimica Acta Part B: Atomic Spectroscopy 111 (2015), 46-51.
• MORAES D.P., SVOBODA M., MATOUŠEK T., FLORES E.M.M., DĚDINA J.: Selective Generation of Substituted Arsines - Cryotrapping - Atomic Absorption Spectrometry for Arsenic Speciation Analysis in N-methylglucamine antimonate. Journal of Analytical Atomic Spectrometry, 27 (2012), 1734-1742.
• CURRIER J.M., SVOBODA M., MATOUŠEK T., DĚDINA J., STÝBLO M.: Direct Analysis and Stability of Methylated Trivalent Arsenic Metabolites in Cells and Tissues. Metallomics, 3 (2011), 1347-1354.
• TAURKOVÁ P., SVOBODA M., MUSIL S., MATOUŠEK, T.: Loss of di- and trimethylarsine on Nafion membrane dryers following hydride generation. Journal of Analytical Atomic Spectrometry, 26 (2011), 220-223.
• CURRIER J., SVOBODA M., DE MORAES D., MATOUŠEK T., DĚDINA J., STÝBLO M.: Direct Analysis of Methylated Trivalent Arsenicals in Mouse Liver by Hydride Generation-Cryotrapping-Atomic Absorption Spectrometry. Chemical Research in Toxicology, 24 (2011), 478-480.
• MATOUŠEK T., HERNANDÉZ-ZAVALA A., SVOBODA M., LANGEROVÁ L., ADAIR B. M., DROBNÁ Z., THOMAS D. J., STÝBLO M., DĚDINA J.: Oxidation State Specific Generation of Arsines from Methylated Arsenicals Based on L-Cysteine Treatment in Buffered Media for Speciation Analysis by Hydride Generation-Automated Cryotrapping-Gas Chromatography-Atomic Absorption Spectrometry with the Multiatomizer. Spectrochimica Acta Part B: Atomic Spectroscopy, 63 (2008), 396–406.